D
Darius Moradpour
Researcher at University of Lausanne
Publications - 304
Citations - 23849
Darius Moradpour is an academic researcher from University of Lausanne. The author has contributed to research in topics: Hepatitis C virus & Virus. The author has an hindex of 72, co-authored 287 publications receiving 22406 citations. Previous affiliations of Darius Moradpour include University of Freiburg & University Hospital of Lausanne.
Papers
More filters
Journal ArticleDOI
Comparative genetic analyses point to HCP5 as susceptibility locus for HCV-associated hepatocellular carcinoma.
Christian M. Lange,Christian M. Lange,Stéphanie Bibert,Jean-François Dufour,Cristina Cellerai,Andreas Cerny,Markus H. Heim,Laurent Kaiser,Raffaele Malinverni,Beat Müllhaupt,Francesco Negro,David Semela,Darius Moradpour,Zoltán Kutalik,Zoltán Kutalik,Pierre-Yves Bochud +15 more
TL;DR: The data confirms the MICA/HCP5 region as susceptibility locus for HCV-related HCC and identifies rs2244546 in HCP5 as a novel tagging SNP, suggesting that rs 2244546 may better tag a putative true variant than the originally identified SNPs.
Journal ArticleDOI
Efficient Gene Transfer into Mammalian Cells with Cholesteryl-Spermidine☆
TL;DR: Cholesteryl-spermidine (Transfectall) represents a novel cationic compound for efficient transfection of cultured cells in vitro and has the potential to be used for gene transfer in vivo.
Journal ArticleDOI
Early transjugular intrahepatic portosystemic shunt in cirrhotic patients with acute variceal bleeding: A systematic review and meta-analysis of controlled trials
Pierre Deltenre,Eric Trepo,Marika Rudler,Alberto Monescillo,Montserrat Fraga,Alban Denys,Christopher Doerig,Nicolas Fournier,Christophe Moreno,Darius Moradpour,Christophe Bureau,Dominique Thabut +11 more
TL;DR: Cirrhotic patients with AVB treated with earlyTIPSS had lower death rates and lower rates of clinically significant bleeding within 1 year compared with patients treated without early TIPSS.
Journal ArticleDOI
Clinical phenotype and outcome of hepatitis E virus-associated neuralgic amyotrophy.
Jeroen J.J. van Eijk,Harry R. Dalton,P. Ripellino,Richard G. Madden,Catherine Jones,Miriam Fritz,Claudio Gobbi,Giorgia Melli,Emanuela Pasi,Jenny Herrod,Rebecca Lissmann,Hafiz Hamad Ashraf,Mohamed Abdelrahim,Omar A.B.A.L. Masri,Montserrat Fraga,David H. Benninger,Thierry Kuntzer,Vincent Aubert,Roland Sahli,Darius Moradpour,Hélène Blasco-Perrin,Shahram Attarian,René Gerolami,Philippe Colson,Maria Teresa Giordani,Johannes Hartl,Sven Pischke,Nan X. Lin,Brendan McLean,Richard P. Bendall,Marcus Panning,Jean-Marie Péron,Nassim Kamar,Jacques Izopet,Bart C. Jacobs,Nens van Alfen,Baziel G.M. van Engelen +36 more
TL;DR: Patients with HEV-NA are usually anicteric and have a distinct clinical phenotype, with predominately bilateral asymmetrical involvement of, and more extensive damage to, the brachial plexus.
Journal ArticleDOI
HCV infection induces mitochondrial bioenergetic unbalance: causes and effects.
Claudia Piccoli,Giovanni Quarato,Maria Ripoli,Annamaria D'Aprile,Rosella Scrima,Olga Cela,Domenico Boffoli,Darius Moradpour,Nazzareno Capitanio +8 more
TL;DR: A temporal sequence of events is proposed in the HCV-infected cell whereby the primary alteration consists of a release of Ca(2+) from the endoplasmic reticulum, followed by uptake into mitochondria, which causes successive mitochondrial alterations comprising generation of reactive oxygen and nitrogen species and impairment of the oxidative phosphorylation.