D
David K. Menon
Researcher at University of Cambridge
Publications - 822
Citations - 50694
David K. Menon is an academic researcher from University of Cambridge. The author has contributed to research in topics: Traumatic brain injury & Medicine. The author has an hindex of 102, co-authored 732 publications receiving 40046 citations. Previous affiliations of David K. Menon include Hammersmith Hospital & University of Leeds.
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Cognitive sequelae of head injury: involvement of basal forebrain and associated structures.
TL;DR: It is suggested that cholinergic enhancers may be an effective treatment of cognitive deficits post head injury and reduced grey matter density in the head injured group in the basal forebrain, the hippocampal formation and regions of the neocortex is consistent with Cholinergic dysfunction.
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Changes in resting neural connectivity during propofol sedation.
TL;DR: This data show that connectivity of the posterior cingulate changes during sedation to include areas that are not traditionally considered to be part of the default mode network, such as the motor/somatosensory cortices, the anterior thalamic nuclei, and the reticular activating system.
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A management algorithm for adult patients with both brain oxygen and intracranial pressure monitoring: the Seattle International Severe Traumatic Brain Injury Consensus Conference (SIBICC)
Randall M. Chesnut,Sergio Aguilera,Andras Buki,Eileen M. Bulger,Giuseppe Citerio,D. Jamie Cooper,D. Jamie Cooper,Ramon Diaz Arrastia,Michael N. Diringer,Anthony Figaji,Guoyi Gao,Romer Geocadin,Jamshid Ghajar,Odette A. Harris,Alan Hoffer,Peter J. Hutchinson,Mathew Joseph,Ryan S. Kitagawa,Geoffrey T. Manley,Stephan A. Mayer,David K. Menon,Geert Meyfroidt,Daniel B. Michael,Mauro Oddo,David O. Okonkwo,Mayur B. Patel,Claudia S. Robertson,Jeffrey V. Rosenfeld,Jeffrey V. Rosenfeld,Andres M. Rubiano,Juan Sahuquillo,Franco Servadei,Lori Shutter,Deborah M. Stein,Nino Stocchetti,Nino Stocchetti,Fabio Silvio Taccone,Shelly D. Timmons,Eve C. Tsai,Jamie S. Ullman,Paul M. Vespa,Walter Videtta,David W. Wright,Christopher Zammit,Gregory W.J. Hawryluk +44 more
TL;DR: These protocols are intended to assist clinicians in the management of patients with both intracranial pressure (ICP) and brain oxygen monitors but they do not reflect either a standard-of-care or a substitute for thoughtful individualized management.
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Unilateral transplantation of human primary fetal tissue in four patients with Huntington’s disease: NEST-UK safety report ISRCTN no 36485475
Anne Elizabeth Rosser,Roger A. Barker,Timothy Harrower,Colin Watts,M. Farrington,Aileen K Ho,Rowan M Burnstein,David K. Menon,Jonathan H. Gillard,John D. Pickard,Stephen B. Dunnett +10 more
TL;DR: Unilateral transplantation of human fetal striatal tissue in patients with HD is safe and feasible, and there was no evidence that the procedure accelerated the course of the disease.
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Intrinsic Activated Microglia Map to the Peri-infarct Zone in the Subacute Phase of Ischemic Stroke
Christopher J. Price,Dechao Wang,David K. Menon,Joe V. Guadagno,Marcel C. Cleij,Tim D. Fryer,Franklin I. Aigbirhio,Jean-Claude Baron,Elizabeth A. Warburton +8 more
TL;DR: In ischemic stroke patients, minimal activation of microglia is seen before 72 hours and extending to 30 days in core infarction, contralateral hemisphere, and peri-infarct zone, suggesting a therapeutic opportunity that extends beyond time windows traditionally reserved for neuroprotection.