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Edward Giovannucci

Researcher at Harvard University

Publications -  1819
Citations -  202335

Edward Giovannucci is an academic researcher from Harvard University. The author has contributed to research in topics: Cancer & Prostate cancer. The author has an hindex of 206, co-authored 1671 publications receiving 179875 citations. Previous affiliations of Edward Giovannucci include University of California, San Francisco & American Cancer Society.

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Harvard Report on Cancer Prevention. Volume 3: prevention of colon cancer in the United States.

TL;DR: The pathogenesis of this disease and the burden it presents to the United States is reviewed and modi®able risk factors for colon cancer are reviewed and the evidence for screening as a preventive measure is summarized.
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Dietary fiber and distal colorectal adenoma in men.

TL;DR: It is suggested that soluble fiber may be particularly important in reducing risk of adenomatous polyps of the distal colon and support national dietary guidelines of increasing fruit consumption.
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Discovery of Colorectal Cancer PIK3CA Mutation as Potential Predictive Biomarker: Power and Promise of Molecular Pathological Epidemiology

TL;DR: Recent ‘molecular pathological epidemiology’ (MPE) research has shown that aspirin use is associated with better prognosis and clinical outcome in PIK3CA-mutated colorectal carcinoma, suggesting somatic Pik3CA mutation as a molecular biomarker that predicts response to aspirin therapy.
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Epidemiologic Characteristics of Prostate Cancer

TL;DR: Dietary factors appear to hold the most promise for primary prevention, but the precise factors and mechanisms need to be better understood.
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Interaction of estrogen therapy with calcium and vitamin D supplementation on colorectal cancer risk: reanalysis of Women's Health Initiative randomized trial.

TL;DR: Results indicate that concurrent estrogen therapy was a strong effect modifier of calcium and vitamin‐D supplementation on colorectal cancer risk, and important biological mechanisms related to the key membrane receptor megalin and estrogen‐dependent protein calbindin are discussed.