Elisa Taschin

TL;DR: The involvement of the MYC-MAX-MXD1 network in the development and progression of neural crest cell tumors is supported and the lack of functional MAX in rat PCC (PC12) cells is supported, which suggests that loss of MAX function is correlated with metastatic potential.

TL;DR: Germline mutations in MAX are responsible for 1.12% of PCC/PGL in patients without evidence of other known mutations and should be considered in the genetic work-up of these patients.

TL;DR: Germline mutations of FP/ TMEM127 were associated with pheochromocytoma but not paraganglioma and occurred in an age group frequently excluded from genetic screening algorithms, and disease-associated mutations disrupt intracellular distribution of the FP/TMEM127 protein.

TL;DR: The SDHA, TMEM127, MAX, and SDHAF2 genes may contribute to hereditary pheochromocytoma and paraganglioma and Gene-specific prevention and/or early detection requires regular, systematic whole-body investigation.

TL;DR: It is demonstrated that tail vein transplantation of mouse amniotic fluid stem (AFS) cells enhances the muscle strength and improves the survival rate of the affected animals and secondary transplants of satellite cells derived from treated mice show that AFS cells integrate into the muscle stem cell compartment and have long‐term muscle regeneration capacity indistinguishable from that of wild‐type‐derived SC.