E
Evelyn Jagoda
Researcher at Harvard University
Publications - 15
Citations - 650
Evelyn Jagoda is an academic researcher from Harvard University. The author has contributed to research in topics: Population & Gene. The author has an hindex of 6, co-authored 13 publications receiving 395 citations. Previous affiliations of Evelyn Jagoda include University of Cambridge.
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Journal ArticleDOI
Genomic analyses inform on migration events during the peopling of Eurasia
Luca Pagani,Luca Pagani,Luca Pagani,Daniel Lawson,Evelyn Jagoda,Evelyn Jagoda,Alexander Mörseburg,Anders Eriksson,Anders Eriksson,Mario Mitt,Florian Clemente,Florian Clemente,Georgi Hudjashov,Georgi Hudjashov,Georgi Hudjashov,Michael DeGiorgio,Lauri Saag,Jeffrey D. Wall,Alexia Cardona,Reedik Mägi,Melissa A. Wilson Sayres,Melissa A. Wilson Sayres,Sarah Kaewert,Charlotte E. Inchley,Christiana L. Scheib,Mari Järve,Monika Karmin,Monika Karmin,Monika Karmin,Guy S. Jacobs,Tiago Antao,Florin Mircea Iliescu,Alena Kushniarevich,Alena Kushniarevich,Qasim Ayub,Chris Tyler-Smith,Yali Xue,Bayazit Yunusbayev,Kristiina Tambets,Chandana Basu Mallick,Lehti Saag,Elvira Pocheshkhova,George Andriadze,Craig Muller,Michael C. Westaway,David M. Lambert,Grigor Zoraqi,Shahlo Turdikulova,Dilbar Dalimova,Zhaxylyk Sabitov,Gazi Nurun Nahar Sultana,Joseph Lachance,Joseph Lachance,Sarah A. Tishkoff,Kuvat T. Momynaliev,Jainagul Isakova,Larisa Damba,Marina Gubina,Pagbajabyn Nymadawa,Irina Evseeva,L. A. Atramentova,Olga Utevska,François-Xavier Ricaut,Nicolas Brucato,Herawati Sudoyo,Thierry Letellier,Murray P. Cox,Nikolay A. Barashkov,Vedrana Škaro,Lejla Mulahasanovic,Dragan Primorac,Hovhannes Sahakyan,Hovhannes Sahakyan,Maru Mormina,Christina A. Eichstaedt,Christina A. Eichstaedt,Daria V. Lichman,Daria V. Lichman,S M Abdullah,Gyaneshwer Chaubey,Joseph Wee,Evelin Mihailov,A. S. Karunas,Sergei Litvinov,Sergei Litvinov,Rita Khusainova,N. V. Ekomasova,V. L. Akhmetova,I. M. Khidiyatova,Damir Marjanović,Levon Yepiskoposyan,Doron M. Behar,Elena Balanovska,Andres Metspalu,Miroslava Derenko,Boris Malyarchuk,Mikhail Voevoda,Mikhail Voevoda,Mikhail Voevoda,Sardana A. Fedorova,Ludmila P. Osipova,Ludmila P. Osipova,Marta Mirazón Lahr,Pascale Gerbault,Matthew Leavesley,Matthew Leavesley,Andrea Bamberg Migliano,Michael D. Petraglia,Oleg Balanovsky,Elza Khusnutdinova,Ene Metspalu,Ene Metspalu,Mark G. Thomas,Andrea Manica,Rasmus Nielsen,Richard Villems,Richard Villems,Richard Villems,Eske Willerslev,Toomas Kivisild,Toomas Kivisild,Mait Metspalu +121 more
TL;DR: A genetic signature in present-day Papuans that suggests that at least 2% of their genome originates from an early and largely extinct expansion of anatomically modern humans (AMHs) out of Africa earlier than 75,000 years ago is found.
Journal ArticleDOI
Evolutionary Selection and Constraint on Human Knee Chondrocyte Regulation Impacts Osteoarthritis Risk.
Daniel Richard,Zun Liu,Jiaxue Cao,Jiaxue Cao,Ata M. Kiapour,Jessica Willen,Siddharth Yarlagadda,Evelyn Jagoda,Vijaya B. Kolachalama,Jakob T. Sieker,Jakob T. Sieker,Gary H. Chang,Pushpanathan Muthuirulan,Mariel Young,Anand O. Masson,Johannes Konrad,Shayan Hosseinzadeh,David E. Maridas,Vicki Rosen,Roman Krawetz,Neil T. Roach,Terence D. Capellini,Terence D. Capellini +22 more
TL;DR: This work proposes a model whereby genetic violations to regulatory constraint, tolerated during knee development, lead to adult pathology, and discovers a causal enhancer variant present in billions of people at a risk locus (GDF5-UQCC1), showing how it impacts mouse knee-shape and osteoarthritis.
Journal ArticleDOI
Compatibility rules of human enhancer and promoter sequences
Drew T. Bergman,Thouis R. Jones,Vincent Liu,Judhajeet Ray,Evelyn Jagoda,Layla Siraj,Helen Y. Kang,Joseph Nasser,Michael Kane,Antonio Ray Rios,Sharon R. Grossman,Charles P. Fulco,Eric S. Lander,Jesse M. Engreitz +13 more
TL;DR: In this paper , the authors identify simple rules for enhancer-promoter compatibility, whereby most enhancers activate all promoters by similar amounts, and intrinsic enhancer and promoter activities multiplicatively combine to determine RNA output (R2 = 0.82).
Journal ArticleDOI
Disentangling Immediate Adaptive Introgression from Selection on Standing Introgressed Variation in Humans.
Evelyn Jagoda,Daniel Lawson,Jeffrey D. Wall,David M. Lambert,Craig Muller,Michael C. Westaway,Matthew Leavesley,Terence D. Capellini,Marta Mirazón Lahr,Pascale Gerbault,Mark G. Thomas,Andrea Bamberg Migliano,Eske Willerslev,Mait Metspalu,Luca Pagani +14 more
TL;DR: The results suggest that iAI may not represent the full picture of positive selection on archaically introgressed haplotypes in humans and that more work needs to be done to analyze the role of SI in the archaic introgression landscape of living humans.
Journal ArticleDOI
Epigenetic profiling of growth plate chondrocytes sheds insight into regulatory genetic variation influencing height.
Michael H. Guo,Michael H. Guo,Michael H. Guo,Zun Liu,Jessie Willen,Cameron P Shaw,Daniel Richard,Daniel Richard,Evelyn Jagoda,Andrew C. Doxey,Joel N. Hirschhorn,Joel N. Hirschhorn,Joel N. Hirschhorn,Terence D. Capellini,Terence D. Capellini +14 more
TL;DR: To uncover mechanisms by which height GWAS variants function, epigenetic profiling of murine femoral growth plates revealed compelling mechanisms forGWAS variants at specific loci.