F
Felipe A. Vieira Braga
Researcher at University of Amsterdam
Publications - 32
Citations - 2233
Felipe A. Vieira Braga is an academic researcher from University of Amsterdam. The author has contributed to research in topics: Immune system & Cytotoxic T cell. The author has an hindex of 12, co-authored 27 publications receiving 1301 citations. Previous affiliations of Felipe A. Vieira Braga include Radboud University Nijmegen & Wellcome Trust.
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Journal ArticleDOI
A cellular census of human lungs identifies novel cell states in health and in asthma.
Felipe A. Vieira Braga,Gozde Kar,Marijn Berg,Orestes A Carpaij,Krzysztof Polanski,Lukas M. Simon,Sharon Brouwer,Tomás Gomes,Laura Hesse,Jian Jiang,Eirini S. Fasouli,Mirjana Efremova,Roser Vento-Tormo,Carlos Talavera-López,Marnix R. Jonker,Karen Affleck,Subarna Palit,Paulina M. Strzelecka,Paulina M. Strzelecka,Helen V. Firth,Krishnaa T. Mahbubani,Ana Cvejic,Ana Cvejic,Kerstin B. Meyer,Kourosh Saeb-Parsy,Marjan Luinge,Corry-Anke Brandsma,Wim Timens,Ilias Angelidis,Maximilian Strunz,Gerard H. Koppelman,Antoon J. M. van Oosterhout,Herbert B. Schiller,Fabian J. Theis,Maarten van den Berge,Martijn C. Nawijn,Sarah A. Teichmann,Sarah A. Teichmann +37 more
TL;DR: Single-cell transcriptomics reveals immune and stromal compartment remodeling, including the enrichment of unique populations of epithelial cells and CD4+ T cells, in asthmatic lungs.
Journal ArticleDOI
Single-cell transcriptomes from human kidneys reveal the cellular identity of renal tumors
Matthew D. Young,Thomas J. Mitchell,Thomas J. Mitchell,Thomas J. Mitchell,Felipe A. Vieira Braga,Maxine G. B. Tran,Benjamin J. Stewart,John R. Ferdinand,Grace Collord,Grace Collord,Grace Collord,Rachel A. Botting,Dorin-Mirel Popescu,Kevin W. Loudon,Roser Vento-Tormo,Emily Stephenson,Alex Cagan,Sarah J. Farndon,Sarah J. Farndon,Sarah J. Farndon,Martin Del Castillo Velasco-Herrera,Charlotte Guzzo,Nathan Richoz,Lira Mamanova,Tevita Aho,James N. Armitage,Antony C. P. Riddick,Imran Mushtaq,Stephen Farrell,Dyanne Rampling,James Nicholson,James Nicholson,Andrew Filby,Johanna Burge,Steven Lisgo,Patrick H. Maxwell,Susan Lindsay,Anne Y. Warren,Grant D. Stewart,Grant D. Stewart,Neil J. Sebire,Neil J. Sebire,Nicholas Coleman,Nicholas Coleman,Muzlifah Haniffa,Muzlifah Haniffa,Sarah A. Teichmann,Menna R. Clatworthy,Menna R. Clatworthy,Sam Behjati,Sam Behjati,Sam Behjati +51 more
TL;DR: It is determined that Wilms tumor, a pediatric kidney cancer, originates from aberrant fetal cells, whereas adult kidney cancers are likely derived from a specific subtype of proximal convoluted tubular cell.
Journal ArticleDOI
Spatiotemporal immune zonation of the human kidney
Benjamin J. Stewart,Benjamin J. Stewart,Benjamin J. Stewart,John R. Ferdinand,Matthew D. Young,Thomas J. Mitchell,Thomas J. Mitchell,Thomas J. Mitchell,Kevin W. Loudon,Kevin W. Loudon,Alexandra M. Riding,Alexandra M. Riding,Nathan Richoz,Gordon L. Frazer,Joy Ursula Lauren Staniforth,Felipe A. Vieira Braga,Rachel A. Botting,Dorin-Mirel Popescu,Roser Vento-Tormo,Emily Stephenson,Alex Cagan,Sarah J. Farndon,Sarah J. Farndon,Sarah J. Farndon,Krzysztof Polanski,Mirjana Efremova,Kile Green,Martin Del Castillo Velasco-Herrera,Charlotte Guzzo,Grace Collord,Grace Collord,Grace Collord,Lira Mamanova,Tevita Aho,James N. Armitage,Antony C. P. Riddick,Imran Mushtaq,Stephen Farrell,Dyanne Rampling,James Nicholson,James Nicholson,Andrew Filby,Johanna Burge,Steven Lisgo,Susan Lindsay,Marc Bajénoff,Anne Y. Warren,Grant D. Stewart,Grant D. Stewart,Neil J. Sebire,Neil J. Sebire,Nicholas Coleman,Nicholas Coleman,Muzlifah Haniffa,Muzlifah Haniffa,Sarah A. Teichmann,Sarah A. Teichmann,Sam Behjati,Sam Behjati,Sam Behjati,Menna R. Clatworthy,Menna R. Clatworthy,Menna R. Clatworthy +62 more
TL;DR: This study provides a global overview of how the immune landscape of the human kidney is zonated to counter the dominant immunological challenge.
Journal ArticleDOI
The Human Lung Cell Atlas: A High-Resolution Reference Map of the Human Lung in Health and Disease
Herbert B. Schiller,Daniel T. Montoro,Lukas M. Simon,Emma L. Rawlins,Kerstin B. Meyer,Maximilian Strunz,Felipe A. Vieira Braga,Wim Timens,Gerard H. Koppelman,Gerard H. Koppelman,G. R. Scott Budinger,Janette K. Burgess,Avinash Waghray,Maarten van den Berge,Fabian J. Theis,Aviv Regev,Naftali Kaminski,Jayaraj Rajagopal,Sarah A. Teichmann,Alexander V. Misharin,Martijn C. Nawijn +20 more
TL;DR: The rationale, the approach and the expected impact of a Human Lung Cell Atlas, which aims to characterize all cells in the healthy human body, are presented.
Journal ArticleDOI
Gene expression variability across cells and species shapes innate immunity
Tzachi Hagai,Tzachi Hagai,Xi Chen,Ricardo J. Miragaia,Ricardo J. Miragaia,Raghd Rostom,Raghd Rostom,Tomás Gomes,Natalia Kunowska,Johan Henriksson,Jong-Eun Park,Valentina Proserpio,Giacomo Donati,Lara Bossini-Castillo,Felipe A. Vieira Braga,Guy Naamati,James Fletcher,Emily Stephenson,Peter Vegh,Gosia Trynka,Ivanela Kondova,Mike Dennis,Muzlifah Haniffa,Armita Nourmohammad,Armita Nourmohammad,Michael Lässig,Sarah A. Teichmann,Sarah A. Teichmann,Sarah A. Teichmann +28 more
TL;DR: The innate immune response’s transcriptional divergence between species and variability in expression among cells is characterized, suggesting that this expression pattern has evolved as a mechanism for fine-tuned regulation to achieve an effective but balanced response.