R
Roser Vento-Tormo
Researcher at Wellcome Trust Sanger Institute
Publications - 75
Citations - 8679
Roser Vento-Tormo is an academic researcher from Wellcome Trust Sanger Institute. The author has contributed to research in topics: Biology & Medicine. The author has an hindex of 23, co-authored 47 publications receiving 4248 citations. Previous affiliations of Roser Vento-Tormo include University of Cambridge.
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Journal ArticleDOI
CellPhoneDB: inferring cell-cell communication from combined expression of multi-subunit ligand-receptor complexes.
TL;DR: The structure and content of CellPhoneDB is outlined, procedures for inferring cell–cell communication networks from single-cell RNA sequencing data are provided and a practical step-by-step guide to help implement the protocol is presented.
Journal ArticleDOI
Single-cell reconstruction of the early maternal–fetal interface in humans
Roser Vento-Tormo,Roser Vento-Tormo,Mirjana Efremova,Rachel A. Botting,Margherita Y. Turco,Miquel Vento-Tormo,Kerstin B. Meyer,Jong-Eun Park,Emily Stephenson,Krzysztof Polanski,Angela Goncalves,Angela Goncalves,Lucy Gardner,Staffan Holmqvist,Johan Henriksson,Angela Zou,Andrew M. Sharkey,Ben Millar,Barbara A. Innes,Laura Wood,Anna Wilbrey-Clark,Rebecca Payne,Martin A. Ivarsson,Steve Lisgo,Andrew Filby,David H. Rowitch,Judith N. Bulmer,Gavin J. Wright,Michael J. T. Stubbington,Muzlifah Haniffa,Muzlifah Haniffa,Ashley Moffett,Sarah A. Teichmann,Sarah A. Teichmann,Sarah A. Teichmann +34 more
TL;DR: A single-cell atlas of the maternal–fetal interface reveals the cellular organization of the decidua and placenta, and the interactions that are critical for placentation and reproductive success, and develops a repository of ligand–receptor complexes and a statistical tool to predict the cell–cell communication via these molecular interactions.
Journal ArticleDOI
Resolving the fibrotic niche of human liver cirrhosis at single cell level
Prakash Ramachandran,Ross Dobie,John R. Wilson-Kanamori,Elena Dora,Beth E. P. Henderson,N T Luu,N T Luu,Jordan R. Portman,Kylie P. Matchett,M Brice,John A. Marwick,Richard S Taylor,Mirjana Efremova,Roser Vento-Tormo,Neil O. Carragher,Timothy J. Kendall,Jonathan A. Fallowfield,Ewen M Harrison,David R. Mole,David R. Mole,Stephen J. Wigmore,Stephen J. Wigmore,Philip N. Newsome,Philip N. Newsome,Christopher J. Weston,Christopher J. Weston,John P. Iredale,Frank Tacke,Jeffrey W. Pollard,Jeffrey W. Pollard,Chris P. Ponting,John C. Marioni,John C. Marioni,John C. Marioni,Sarah A. Teichmann,Sarah A. Teichmann,Sarah A. Teichmann,Neil C. Henderson +37 more
TL;DR: Analysis of transcriptomes of more than 100,000 single human cells yields molecular definitions for non-parenchymal cell types that are found in healthy and cirrhotic human liver, and identifies markers for scar-associated macrophages and endothelial cells.
Journal ArticleDOI
Exponential scaling of single-cell RNA-seq in the past decade.
Valentine Svensson,Valentine Svensson,Roser Vento-Tormo,Sarah A. Teichmann,Sarah A. Teichmann +4 more
TL;DR: In this paper, the authors highlight the key technological developments that have enabled the growth in the data obtained from single-cell RNA-seq experiments, and highlight the advantages of using large numbers of cells.
Journal ArticleDOI
A cellular census of human lungs identifies novel cell states in health and in asthma.
Felipe A. Vieira Braga,Gozde Kar,Marijn Berg,Orestes A Carpaij,Krzysztof Polanski,Lukas M. Simon,Sharon Brouwer,Tomás Gomes,Laura Hesse,Jian Jiang,Eirini S. Fasouli,Mirjana Efremova,Roser Vento-Tormo,Carlos Talavera-López,Marnix R. Jonker,Karen Affleck,Subarna Palit,Paulina M. Strzelecka,Paulina M. Strzelecka,Helen V. Firth,Krishnaa T. Mahbubani,Ana Cvejic,Ana Cvejic,Kerstin B. Meyer,Kourosh Saeb-Parsy,Marjan Luinge,Corry-Anke Brandsma,Wim Timens,Ilias Angelidis,Maximilian Strunz,Gerard H. Koppelman,Antoon J. M. van Oosterhout,Herbert B. Schiller,Fabian J. Theis,Maarten van den Berge,Martijn C. Nawijn,Sarah A. Teichmann,Sarah A. Teichmann +37 more
TL;DR: Single-cell transcriptomics reveals immune and stromal compartment remodeling, including the enrichment of unique populations of epithelial cells and CD4+ T cells, in asthmatic lungs.