G
Gina Choe
Researcher at BC Cancer Agency
Publications - 4
Citations - 852
Gina Choe is an academic researcher from BC Cancer Agency. The author has contributed to research in topics: Massive parallel sequencing & Shotgun sequencing. The author has an hindex of 4, co-authored 4 publications receiving 690 citations.
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Journal ArticleDOI
Exhaustive T-cell repertoire sequencing of human peripheral blood samples reveals signatures of antigen selection and a directly measured repertoire size of at least 1 million clonotypes
René L. Warren,J. Douglas Freeman,Thomas Zeng,Gina Choe,Sarah A. Munro,Richard D. Moore,John R. Webb,Robert A. Holt +7 more
TL;DR: It is shown that the sensitivity of sequence-based repertoire profiling is limited by both sequencing depth and sequencing accuracy, and a new, directly measured, lower limit on individual T-cell repertoire size is established.
Journal ArticleDOI
The Integrated Genomic Landscape of Thymic Epithelial Tumors
Milan Radovich,Curtis R. Pickering,Ina Felau,Gavin Ha,Hailei Zhang,Heejoon Jo,Katherine A. Hoadley,Pavana Anur,Jiexin Zhang,Michael D. McLellan,Reanne Bowlby,Thomas Matthew,Ludmila Danilova,Apurva M. Hegde,Jaegil Kim,Mark D.M. Leiserson,Geetika Sethi,Charles Lu,Michael Ryan,Xiaoping Su,Andrew D. Cherniack,Gordon Robertson,Rehan Akbani,Paul T. Spellman,John N. Weinstein,D. Neil Hayes,Ben Raphael,Tara M. Lichtenberg,Kristen M. Leraas,Jean C. Zenklusen,Adrian Ally,Elizabeth L. Appelbaum,J. Todd Auman,Miruna Balasundaram,Saianand Balu,Madhusmita Behera,Rameen Beroukhim,Mario Berrios,Giovanni Blandino,Tom Bodenheimer,Moiz S. Bootwalla,Jay Bowen,Denise Brooks,Flavio Mavignier Carcano,Rebecca Carlsen,André Lopes Carvalho,Patricia Castro,Lara Chalabreysse,Lynda Chin,Juok Cho,Gina Choe,Eric Chuah,Sudha Chudamani,Carrie Cibulskis,Leslie Cope,Matthew G. Cordes,Daniel Crain,Erin Curley,Timothy Defreitas,John A. Demchok,Frank C. Detterbeck,Noreen Dhalla,Hendrik Dienemann,W. Jeff Edenfield,Francesco Facciolo,Martin L. Ferguson,Scott Frazer,Catrina Fronick,Lucinda Fulton,Robert S. Fulton,Stacey Gabriel,Johanna Gardner,Julie M. Gastier-Foster,Nils Gehlenborg,Mark Gerken,Gad Getz,David I. Heiman,Shital Hobensack,Andrea Holbrook,Robert A. Holt,Alan P. Hoyle,Carolyn M. Hutter,Michael Ittmann,Stuart R. Jefferys,Corbin D. Jones,Steven J.M. Jones,Katayoon Kasaian,Patrick K. Kimes,Phillip H. Lai,Peter W. Laird,Michael S. Lawrence,Pei Lin,Jia Liu,Laxmi Lolla,Yiling Lu,Yussanne Ma,Dennis T. Maglinte,David Mallery,Elaine R. Mardis,Marco A. Marra,Julie S. Martin,Michael Mayo,Sam Meier,Michael Meister,Shaowu Meng,Matthew Meyerson,Piotr A. Mieczkowski,Christopher A. Miller,Gordon B. Mills,Richard A. Moore,Scott Morris,Lisle E. Mose,Thomas Muley,Andrew J. Mungall,Karen Mungall,Rashi Naresh,Yulia Newton,Michael S. Noble,Taofeek K. Owonikoko,Joel S. Parker,Joseph Paulaskis,Robert Penny,Charles M. Perou,Corinne Perrin,Todd Pihl,Amie Radenbaugh,Suresh S. Ramalingam,Nilsa C. Ramirez,Ralf J. Rieker,Jeffrey Roach,Sara Sadeghi,Gordon Saksena,Jacqueline E. Schein,Heather Schmidt,Steven E. Schumacher,Candace Shelton,Troy Shelton,Yan Shi,Juliann Shih,Gabriel Sica,Henrique César Santejo Silveira,Janae V. Simons,Payal Sipahimalani,Tara Skelly,Heidi J. Sofia,Matthew G. Soloway,Joshua M. Stuart,Qiang Sun,Angela Tam,Donghui Tan,Roy Tarnuzzer,Nina Thiessen,David Van Den Berg,Mohammad A. Vasef,Umadevi Veluvolu,Doug Voet,Vonn Walter,Yunhu Wan,Zhining Wang,Arne Warth,Cleo-Aron Weis,Daniel J. Weisenberger,Matthew D. Wilkerson,Lisa Wise,Tina Wong,Hsin-Ta Wu,Ye Wu,Liming Yang,Jiashan Zhang,Erik Zmuda,Junya Fujimoto,Cristovam Scapulatempo-Neto,Andre L. Moreira,David M. Hwang,James Huang,Mirella Marino,Robert Korst,Giuseppe Giaccone,Yesim Gökmen-Polar,Sunil Badve,Arun Rajan,Philipp Ströbel,Nicolas Girard,Ming-Sound Tsao,Alexander Marx,Anne S. Tsao,Patrick J. Loehrer +186 more
TL;DR: A molecular link between thymoma and the autoimmune disease myasthenia gravis is identified, characterized by tumoral overexpression of muscle autoantigens, and increased aneuploidy.
Journal ArticleDOI
Derivation of HLA types from shotgun sequence datasets
René L. Warren,Gina Choe,Douglas J Freeman,Mauro Castellarin,Sarah Munro,Richard A. Moore,Robert A. Holt,Robert A. Holt +7 more
TL;DR: HLAminer, a computational method for identifying HLA alleles directly from shotgun sequence datasets that circumvents the additional time and cost of generating HLA-specific data and capitalizes on the increasing accessibility and affordability of massively parallel sequencing.
Journal ArticleDOI
Erratum: Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles (Cell Reports (2017) 18(11) (2780–2794) (S2211124717302140) (10.1016/j.celrep.2017.02.033))
Vincenzo Cardinale,Eugenio Gaudio,Domenico Alvaro,Antonio Franchitto,Jean-Pierre A. Kocher,Timothy Defreitas,Robert S. Fulton,Robert Penny,André Lopes Carvalho,John N. Weinstein,Roeland Verhaak,Jay Bowen,M.M. Matsushita,Piotr A. Mieczkowski,Stacey Gabriel,Rachna T. Shroff,Mario Berrios,David E. Kleiner,David Mallery,Yunhu Wan,Zixing Wang,Qiang Sun,Joshua M. Stuart,Eric Chuah,Michael Mayo,Martin L. Ferguson,Gordon Saksena,Suhn K. Rhie,Andrew J. Mungall,Saianand Balu,Juok Cho,Andrew D. Cherniack,H. Stoppler,Ronglai Shen,Kimberley Evason,Pei Lin,Richard A. Moore,Chia Chin Wu,Lawrence N. Kwong,Angela Tam,Andrea Holbrook,Erik Zmuda,Mitesh J. Borad,Loretta K. Allotey,Catrina Fronick,Julie M. Gastier-Foster,A.G. Robertson,Rehan Akbani,Catherine D. Moser,Steven E. Schumacher,Jia Liu,Juliann Shih,Peter W. Laird,Josh Stuart,Margi Sheth,Marie-Claude Gingras,Elaine R. Mardis,J.T. Auman,Jacqueline E. Schein,Jeffrey Roach,Yussanne Ma,K. Mungall,Giannicola Genovese,Maria Consiglia Bragazzi,Joel S. Parker,Johanna Gardner,W.K. Rathmell,Denise Brooks,Lisle E. Mose,Tara Skelly,Shaowu Meng,Elizabeth L. Appelbaum,Mi Ni Huang,Youyong Lu,Gad Getz,Arshi Arora,Mark Gerken,Gian Luca Grazi,Jesper B. Andersen,Erin Curley,Corbin D. Jones,Siyuan Zheng,Steven J.M. Jones,Douglas Voet,W.C. Foo,Ed Reznik,D. Alvaro,Lixing Yang,Rashi Naresh,Roongruedee Chaiteerakij,Rameen Beroukhim,Ju Dong Yang,Heidi J. Sofia,Jean C. Zenklusen,Scott Morris,Tom Bodenheimer,Noreen Dhalla,Wenbin Liu,V. Cardinale,Reanne Bowlby,Nilsa C. Ramirez,Oliver F. Bathe,Adrian Ally,Joseph Paulauskis,Charles M. Perou,Apurva M. Hegde,Heather K. Schmidt,Roy Tarnuzzer,Nicolas Stransky,Stuart R. Jefferys,A.X. Zhu,Apurva M. Hegde,Michael Torbenson,Julian M. Hess,Miruna Balasundaram,Farshad Farshidfar,Amie Radenbaugh,Richard A. Gibbs,Rebecca Carlsen,Toshinori Hinoue,Ina Felau,Katayoon Kasaian,Nasra H. Giama,Daniel Crain,Nils Gehlenborg,A.J. McRee,Matthew G. Soloway,Sudha Chudamani,Li Ding,T. Mounajjed,Lewis R. Roberts,Nina Thiessen,Phillip H. Lai,Ewan A. Gibb,Felice Giuliante,Daniel R. O'Brien,Robert A. Holt,Christopher A. Miller,Lori Boice,Lynda Chin,Guido Carpino,Rose A.M. De,D Wheeler,Eve Shinbrot,Laxmi Lolla,John A. Demchok,Todd Pihl,Matthew Meyerson,Eugenio Gaudio,Leigh B. Thorne,Robin Kate Kelley,Janae V. Simons,A. Franchitto,Amy H. Perou,Donghui Tan,V. Deshpande,Yan Shi,Yulia Newton,Akinyemi I. Ojesina,GB Mills,L.A. Fulton,Juinhua Zhang,Kyle R. Covington,Alan P. Hoyle,Chandra Pedamallu,Marco A. Marra,Scott Frazer,Michael S. Noble,Kristen M. Leraas,Matthew G. Cordes,Rick K. Wilson,Yang Wu,Bradley A. Murray,Cindy Sander,Carrie Cibulskis,Carolyn M. Hutter,Jong Kyoung Kim,Candace Shelton,Michael S. Lawrence,D.N. Hayes,Tina Wong,Daniel J. Weisenberger,Hongzheng Zhang,Den Berg D.J. Van,Lisa Wise,Sara Sadeghi,Tara M. Lichtenberg,Liu Xi,Gina Choe,Tushar Patel,V.C. Chandan,David I. Heiman,Payal Sipahimalani,Moiz S. Bootwalla,Troy Shelton,Katherine A. Hoadley,Umadevi Veluvolu,Nabeel Bardeesy,Jason Roszik,Sam Meier,Stephen B. Baylin,Michael D. McLellan +201 more