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Gian Luca Grazi

Researcher at University of Bologna

Publications -  276
Citations -  17459

Gian Luca Grazi is an academic researcher from University of Bologna. The author has contributed to research in topics: Liver transplantation & Transplantation. The author has an hindex of 62, co-authored 258 publications receiving 14991 citations. Previous affiliations of Gian Luca Grazi include University of Nevada, Reno.

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Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer.

Katherine A Hoadley, +738 more
- 05 Apr 2018 - 
TL;DR: Molecular similarities among histologically or anatomically related cancer types provide a basis for focused pan-cancer analyses, such as pan-gastrointestinal, Pan-gynecological, pan-kidney, and pan-squamous cancers, and those related by stemness features, which may inform strategies for future therapeutic development.
Journal ArticleDOI

Genomic and Functional Approaches to Understanding Cancer Aneuploidy

Alison M. Taylor, +732 more
- 09 Apr 2018 - 
TL;DR: The genomic and phenotypic correlates of cancer aneuploidy are defined and genome engineering is applied to delete 3p in lung cells, causing decreased proliferation rescued in part by chromosome 3 duplication.
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MiR-221 controls CDKN1C/p57 and CDKN1B/p27 expression in human hepatocellular carcinoma.

TL;DR: It is suggested that miR-221 has an oncogenic function in hepatocarcinogenesis by targeting CD KN1B/p27 and CDKN1C/p57, hence promoting proliferation by controlling cell-cycle inhibitors.