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Ioannis Xenarios
Researcher at University of Lausanne
Publications - 243
Citations - 38456
Ioannis Xenarios is an academic researcher from University of Lausanne. The author has contributed to research in topics: Gene & Genome. The author has an hindex of 71, co-authored 233 publications receiving 34036 citations. Previous affiliations of Ioannis Xenarios include ISREC & École Polytechnique Fédérale de Lausanne.
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Neutrophils and Snail Orchestrate the Establishment of a Pro-tumor Microenvironment in Lung Cancer
Julien Faget,Svenja Groeneveld,Gael Boivin,Martial Sankar,Nadine Zangger,Miguel Garcia,Nicolas Guex,Inti Zlobec,Loïc Steiner,Alessandra Piersigilli,Ioannis Xenarios,Etienne Meylan +11 more
TL;DR: A vicious cycle encompassing neutrophils and Snail to maintain a deleterious tumor microenvironment is proposed and identified a contribution of Gr1+ neutrophil to disease progression.
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CDK9 Regulates AR Promoter Selectivity and Cell Growth through Serine 81 Phosphorylation
Vicki L. Gordon,Shriti Bhadel,Winfried Wunderlich,JoAnn Zhang,Scott B. Ficarro,Sahana Mollah,Jeffrey Shabanowitz,Donald F. Hunt,Ioannis Xenarios,William C. Hahn,Mark R. Conaway,Michael Carey,Daniel Gioeli +12 more
TL;DR: It is suggested that CDK9 phosphorylation of AR S81 is an important step in regulating AR transcriptional activity and prostate cancer cell growth.
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SBML qualitative models: a model representation format and infrastructure to foster interactions between qualitative modelling formalisms and tools.
Claudine Chaouiya,Duncan Berenguier,Sarah M. Keating,Aurélien Naldi,Martijn P. van Iersel,Nicolas Rodriguez,Nicolas Rodriguez,Andreas Dräger,Andreas Dräger,Finja Büchel,Thomas Cokelaer,Bryan Kowal,Benjamin Wicks,Emanuel Gonçalves,Julien Dorier,Michel Page,Michel Page,Pedro T. Monteiro,Pedro T. Monteiro,Axel von Kamp,Ioannis Xenarios,Hidde de Jong,Michael Hucka,Steffen Klamt,Denis Thieffry,Nicolas Le Novère,Nicolas Le Novère,Julio Saez-Rodriguez,Tomáš Helikar +28 more
TL;DR: The Systems Biology Markup Language (SBML) Qualitative Models Package (qual) as discussed by the authors is an extension of the SBML Level 3 standard designed for computer representation of qualitative models of biological networks.
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Probabilistic base calling of Solexa sequencing data
Jacques Rougemont,Jacques Rougemont,Arnaud Amzallag,Arnaud Amzallag,Christian Iseli,Christian Iseli,Laurent Farinelli,Ioannis Xenarios,Ioannis Xenarios,Felix Naef,Felix Naef +10 more
TL;DR: A novel base calling algorithm using model-based clustering and probability theory to identify ambiguous bases and code them with IUPAC symbols is proposed, which improves genome coverage and number of usable tags as compared with Solexa's data processing pipeline by an average of 15%.
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Improving the sensitivity of the sequence profile method.
TL;DR: Improved sequence profile method methods are found to be more sensitive and selective in a number of cases where previous methods have failed to completely separate true members from false positives.