Irene O.C.M. Vroegrijk

TL;DR: It is demonstrated that mice deficient in Nlrp3, apoptosis-associated speck-like protein, and caspase-1 were resistant to the development of high-fat diet-induced obesity, which correlated with protection from obesity-induced insulin resistance, and inhibition of the inflammasome is suggested as a potential therapeutic strategy.

TL;DR: It is concluded that dietary PSO ameliorates high-fat diet induced obesity and insulin resistance in mice, independent of changes in food intake or energy expenditure.

TL;DR: P. berghei ANKA parasites deficient in schizont membrane-associated cytoadherence protein reveal a beneficial role for CD36-mediated tissue sequestration in aiding parasite growth.

TL;DR: The scavenger receptor CD36 facilitates the cellular uptake of long‐chain fatty acids and contributes to the development of high fat diet‐induced obesity through preadipocyte recruitment and adipocyte function.

TL;DR: The data indicate that COX6A2 is a regulator of respiratory uncoupling in muscle and it is demonstrated that a novel and direct link exists between muscle respiratory chain activity and diet-induced obesity/insulin resistance.