J
Jacques Lebras
Researcher at Paris Descartes University
Publications - 3
Citations - 457
Jacques Lebras is an academic researcher from Paris Descartes University. The author has contributed to research in topics: Plasmodium falciparum & Drug resistance. The author has an hindex of 3, co-authored 3 publications receiving 407 citations. Previous affiliations of Jacques Lebras include University of Paris.
Papers
More filters
Journal ArticleDOI
Immunocapture diagnostic assays for malaria using Plasmodium lactate dehydrogenase (pLDH).
Robert C. Piper,Jacques Lebras,Laura Wentworth,Angela Hunt-Cooke,Sandra Houze,Peter L. Chiodini,Michael T. Makler +6 more
TL;DR: Diagnostic tests based on the detection of pLDH are both sensitive and practical for the detection, speciation, and quantitation of all human Plasmodium infections and can also be used to indicate drug-resistant infections.
Journal ArticleDOI
Polymorphisms in Plasmodium falciparum chloroquine Resistance Transporter and Multidrug Resistance 1 Genes: Parasite Risk Factors That Affect Treatment Outcomes for P. falciparum Malaria After Artemether-Lumefantrine and Artesunate-Amodiaquine
Meera Venkatesan,Nahla B Gadalla,Kasia Stepniewska,Prabin Dahal,Christian Nsanzabana,Clarissa Moriera,Ric N. Price,Andreas Mårtensson,Philip J. Rosenthal,Grant Dorsey,Colin J. Sutherland,Philippe J Guerin,Timothy M. E. Davis,Didier Menard,Ishag Adam,George O. Ademowo,Cesar Arze,Frederick N. Baliraine,Nicole Berens-Riha,Anders Björkman,Steffen Borrmann,Francesco Checchi,Meghna Desai,Mehul Dhorda,Abdoulaye Djimde,Badria B. El-Sayed,Teferi Eshetu,Frederick Eyase,Catherine O. Falade,Jean-François Faucher,Gabrielle Fröberg,Anastasia Grivoyannis,Sally Hamour,Sandrine Houzé,Jacob D. Johnson,Erasmus Kamugisha,Simon Kariuki,Jean-René Kiechel,Fred Kironde,Fred Kironde,Poul-Erik Kofoed,Jacques Lebras,Maja Malmberg,Maja Malmberg,Leah Mwai,Leah Mwai,Billy Ngasala,François Nosten,Samuel L. Nsobya,Alexis Nzila,Alexis Nzila,Mary C. Oguike,Sabina Dahlström Otienoburu,Bernhards Ogutu,Jean-Bosco Ouédraogo,Patrice Piola,Patrice Piola,Lars Rombo,Birgit Schramm,A. Fabrice Some,Julie Thwing,Johan Ursing,Rina P. M. Wong,Ahmed Zeynudin,Issaka Zongo,Christopher V. Plowe,Carol Hopkins Sibley,Carol Hopkins Sibley +67 more
TL;DR: Monitoring selection and responding to emerging signs of drug resistance are critical tools for preserving efficacy of artemisinin combination therapies; determination of the prevalence of at least pfcrt K76T and pfmdr1 N86Y should now be routine.
Journal ArticleDOI
Absence of association between Plasmodium falciparum small sub-unit ribosomal RNA gene mutations and in vitro decreased susceptibility to doxycycline
Tiphaine Gaillard,Nathalie Wurtz,Sandrine Houzé,Kanlaya Sriprawat,Chirapat Wangsing,Véronique Hubert,Jacques Lebras,François Nosten,François Nosten,Sébastien Briolant,Bruno Pradines +10 more
TL;DR: The association between polymorphism of the small sub-unit ribosomal RNA apicoplastic gene pfssrRNA and in vitro susceptibilities of P. falciparum isolates to doxycycline was investigated and it was found that the pfSSrRNA gene is not associated with in vitro decreased susceptibility.