S
Sabina Dahlström Otienoburu
Researcher at Johnson C. Smith University
Publications - 6
Citations - 280
Sabina Dahlström Otienoburu is an academic researcher from Johnson C. Smith University. The author has contributed to research in topics: Plasmodium falciparum & Drug resistance. The author has an hindex of 3, co-authored 3 publications receiving 212 citations.
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Journal ArticleDOI
Polymorphisms in Plasmodium falciparum chloroquine Resistance Transporter and Multidrug Resistance 1 Genes: Parasite Risk Factors That Affect Treatment Outcomes for P. falciparum Malaria After Artemether-Lumefantrine and Artesunate-Amodiaquine
Meera Venkatesan,Nahla B Gadalla,Kasia Stepniewska,Prabin Dahal,Christian Nsanzabana,Clarissa Moriera,Ric N. Price,Andreas Mårtensson,Philip J. Rosenthal,Grant Dorsey,Colin J. Sutherland,Philippe J Guerin,Timothy M. E. Davis,Didier Menard,Ishag Adam,George O. Ademowo,Cesar Arze,Frederick N. Baliraine,Nicole Berens-Riha,Anders Björkman,Steffen Borrmann,Francesco Checchi,Meghna Desai,Mehul Dhorda,Abdoulaye Djimde,Badria B. El-Sayed,Teferi Eshetu,Frederick Eyase,Catherine O. Falade,Jean-François Faucher,Gabrielle Fröberg,Anastasia Grivoyannis,Sally Hamour,Sandrine Houzé,Jacob D. Johnson,Erasmus Kamugisha,Simon Kariuki,Jean-René Kiechel,Fred Kironde,Fred Kironde,Poul-Erik Kofoed,Jacques Lebras,Maja Malmberg,Maja Malmberg,Leah Mwai,Leah Mwai,Billy Ngasala,François Nosten,Samuel L. Nsobya,Alexis Nzila,Alexis Nzila,Mary C. Oguike,Sabina Dahlström Otienoburu,Bernhards Ogutu,Jean-Bosco Ouédraogo,Patrice Piola,Patrice Piola,Lars Rombo,Birgit Schramm,A. Fabrice Some,Julie Thwing,Johan Ursing,Rina P. M. Wong,Ahmed Zeynudin,Issaka Zongo,Christopher V. Plowe,Carol Hopkins Sibley,Carol Hopkins Sibley +67 more
TL;DR: Monitoring selection and responding to emerging signs of drug resistance are critical tools for preserving efficacy of artemisinin combination therapies; determination of the prevalence of at least pfcrt K76T and pfmdr1 N86Y should now be routine.
Journal ArticleDOI
Selection of Plasmodium falciparum pfcrt and pfmdr1 polymorphisms after treatment with artesunate–amodiaquine fixed dose combination or artemether–lumefantrine in Liberia
Sabina Dahlström Otienoburu,Oumou Maïga-Ascofaré,Birgit Schramm,Vincent Jullien,Joel J. Jones,Yah Zolia,Pascal Houzé,Elizabeth A. Ashley,Jean-René Kiechel,Philippe J Guerin,Jacques Le Bras,Sandrine Houzé +11 more
TL;DR: Although treatment is highly efficacious, selection of Molecular markers in reinfections could indicate a decreased sensitivity or tolerance of parasites to the current treatments and the baseline prevalence of molecular markers should be closely monitored.
Journal ArticleDOI
An online mapping database of molecular markers of drug resistance in Plasmodium falciparum: the ACT Partner Drug Molecular Surveyor.
Sabina Dahlström Otienoburu,Ignacio Suay,Steven Garcia,Nigel V. Thomas,Suttipat Srisutham,Anders Björkman,Georgina S Humphreys +6 more
TL;DR: The WWARN ACT Partner Drugs Molecular Surveyor summarizes data on resistance markers in the pfmdr1 and pfcrt genes, and is fully accessible, providing users with a rich resource to explore and analyze, and thus utilize a centralized, standardized database for different purposes.
Journal ArticleDOI
Spatiotemporal spread of Plasmodium falciparum mutations for resistance to sulfadoxine-pyrimethamine across Africa, 1990–2020
Jennifer A. Flegg,Georgina S Humphreys,Brenda Montanez,Taryn Strickland,Zaira J Jacome-Meza,Karen I. Barnes,Jaishree Raman,Philippe J Guerin,Carol Hopkins Sibley,Sabina Dahlström Otienoburu +9 more
TL;DR: The WWARN SP Molecular Surveyor database and a set of continuous spatiotemporal surface maps were built to provide users with standardized, current information on resistance marker distribution and prevalence estimates to highlight areas of concern.