M
Marc P. Hoeppner
Researcher at University of Kiel
Publications - 46
Citations - 2376
Marc P. Hoeppner is an academic researcher from University of Kiel. The author has contributed to research in topics: Gene & Genome. The author has an hindex of 20, co-authored 43 publications receiving 1651 citations. Previous affiliations of Marc P. Hoeppner include Linköping University & Science for Life Laboratory.
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Journal ArticleDOI
Structural genomic changes underlie alternative reproductive strategies in the ruff (Philomachus pugnax)
Sangeet Lamichhaney,Guangyi Fan,Fredrik Widemo,Ulrika Gunnarsson,Doreen Schwochow Thalmann,Marc P. Hoeppner,Marc P. Hoeppner,Marc P. Hoeppner,Susanne Kerje,Ulla Gustafson,Chengcheng Shi,He Zhang,Wenbin Chen,Xinming Liang,Leihuan Huang,Jiahao Wang,Enjing Liang,Qiong Wu,Simon Ming-Yuen Lee,Xun Xu,Jacob Höglund,Xin Liu,Leif Andersson,Leif Andersson,Leif Andersson +24 more
TL;DR: Using whole-genome sequencing, this work proposes an evolutionary scenario where the Satellite chromosome arose by a rare recombination event about 500,000 years ago and resolved the enigma of how such complex phenotypic differences can have a simple genetic basis.
Journal ArticleDOI
Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19.
Joana P. Bernardes,Neha Mishra,Florian Tran,Thomas Bahmer,Lena Best,Johanna I. Blase,Dora Bordoni,Jeanette Franzenburg,Ulf Geisen,Jonathan Josephs-Spaulding,Philipp Köhler,Axel Künstner,Elisa Rosati,Anna C. Aschenbrenner,Petra Bacher,Nathan Baran,Teide Boysen,Burkhard Brandt,Niklas Bruse,Jonathan Dörr,Andreas Dräger,Gunnar Elke,David Ellinghaus,Julia Fischer,Michael Forster,Andre Franke,Sören Franzenburg,Norbert Frey,Anette Friedrichs,Janina Fuß,Andreas Glück,Jacob Hamm,Finn Hinrichsen,Marc P. Hoeppner,Simon Imm,Ralf Junker,Sina Kaiser,Ying H. Kan,Rainer Knoll,Christoph Lange,Georg Laue,Clemens Lier,Matthias Lindner,Georgios Marinos,Robert Markewitz,Jacob Nattermann,Rainer Noth,Peter Pickkers,Klaus F. Rabe,Alina Renz,Christoph Röcken,Jan Rupp,Annika Schaffarzyk,Alexander Scheffold,Jonas Schulte-Schrepping,Jonas Schulte-Schrepping,Domagoj Schunk,Dirk Skowasch,Thomas Ulas,Thomas Ulas,Klaus-Peter Wandinger,Michael Wittig,Johannes Zimmermann,Hauke Busch,Bimba F. Hoyer,Christoph Kaleta,Jan Heyckendorf,Matthijs Kox,Jan Rybniker,Stefan Schreiber,Joachim L. Schultze,Joachim L. Schultze,Philip Rosenstiel,Nicholas E. Banovich,Tushar J. Desai,Oliver Eickelberg,Muzlifa Haniffa,Peter Horvath,Jonathan A. Kropski,Robert Lafyatis,Joakim Lundeberg,Kerstin B. Meyer,Martijn C. Nawijn,Marko Nikolic,Jose Ordovas Montanes,Dana Pe'er,Purushothama Rao Tata,Emma L. Rawlins,Aviv Regev,Paul A. Reyfman,Christos Samakovlis,Joachim Schultze,Alex K. Shalek,Douglas P. Shepherd,Jason R. Spence,Sarah A. Teichmann,Fabian J. Theis,Alexander M. Tsankov,Maarten van den Berge,Michael von Papen,Jeffrey A. Whitsett,Laure-Emmanuelle Zaragosi,Angel Angelov,Robert Bals,Alexander Bartholomäus,Anke Becker,Daniela Bezdan,Ezio Bonifacio,Peer Bork,Thomas Clavel,Maria Colme-Tatche,Andreas Diefenbach,Alexander T. Dilthey,Nicole Fischer,Konrad U. Förstner,Julia-Stefanie Frick,Julien Gagneur,Alexander Goesmann,Torsten Hain,Michael Hummel,Stefan Janssen,Jörn Kalinowski,René Kallies,Birte Kehr,Andreas Keller,Sarah Kim-Hellmuth,Christoph Klein,Oliver Kohlbacher,Jan O. Korbel,Ingo Kurth,Markus Landthaler,Yang Li,Kerstin U. Ludwig,Oliwia Makarewicz,Manja Marz,Alice C. McHardy,Christian Mertes,Markus M. Nöthen,Peter Nürnberg,Uwe Ohler,Stephan Ossowski,Jörg Overmann,Silke Peter,Klaus Pfeffer,Anna R. Poetsch,Alfred Pühler,Niklaus Rajewsky,Markus Ralser,Olaf Rieß,Stephan Ripke,Ulisses Nunes da Rocha,Antoine-Emmanuel Saliba,Leif E. Sander,Birgit Sawitzki,Philipp H. Schiffer,Eva-Christina Schulte,Alexander Sczyrba,Oliver Stegle,Jens Stoye,Janne Vehreschild,Jörg Vogel,Max von Kleist,Andreas Walker,Jörn Walter,Dagmar Wieczorek,John Ziebuhr +165 more
TL;DR: The study demonstrates broad cellular effects of SARS-CoV-2 infection beyond classical immune cells and may serve as an entry point to develop biomarkers and targeted treatments of patients with COVID-19.
Journal ArticleDOI
Dense sampling of bird diversity increases power of comparative genomics.
Shaohong Feng,Josefin Stiller,Yuan Deng,Joel Armstrong,Joel Armstrong,Qi Fang,Andrew Hart Reeve,Duo Xie,Guangji Chen,Chunxue Guo,Brant C. Faircloth,Bent O. Petersen,Zongji Wang,Qi Zhou,Qi Zhou,Mark Diekhans,Mark Diekhans,Wanjun Chen,Sergio Andreu-Sánchez,Ashot Margaryan,Ashot Margaryan,Jason T. Howard,Carole A. Parent,George Pacheco,Mikkel-Holger S. Sinding,Lara Puetz,Emily Cavill,Ângela M. Ribeiro,Leopold Eckhart,Jon Fjeldså,Peter A. Hosner,Robb T. Brumfield,Les Christidis,Mads F. Bertelsen,Thomas Sicheritz-Pontén,Dieter Thomas Tietze,Bruce C. Robertson,Gang Song,Gerald Borgia,Santiago Claramunt,Santiago Claramunt,Irby J. Lovette,Saul J. Cowen,Peter Njoroge,John P. Dumbacher,Oliver A. Ryder,Jérôme Fuchs,Michael Bunce,David W. Burt,Joel Cracraft,Guanliang Meng,Shannon J. Hackett,Peter G. Ryan,Knud A. Jønsson,Ian G. Jamieson,Rute R. da Fonseca,Edward L. Braun,Peter Houde,Siavash Mirarab,Alexander Suh,Alexander Suh,Bengt Hansson,Suvi Ponnikas,Hanna Sigeman,Martin Stervander,Martin Stervander,Paul B. Frandsen,Paul B. Frandsen,Henriette van der Zwan,Rencia van der Sluis,Carina Visser,Christopher N. Balakrishnan,Andrew G. Clark,John W. Fitzpatrick,Reed Bowman,Nancy F. Chen,Alison Cloutier,Timothy B. Sackton,Scott V. Edwards,Dustin J. Foote,Subir B. Shakya,Frederick H. Sheldon,Alain Vignal,André E. R. Soares,Beth Shapiro,Jacob González-Solís,Joan Ferrer-Obiol,Julio Rozas,Marta Riutort,Anna Tigano,Anna Tigano,Vicki L. Friesen,Love Dalén,Araxi O. Urrutia,Araxi O. Urrutia,Tamás Székely,Yang Liu,Michael G. Campana,André Corvelo,Robert C. Fleischer,Kim Rutherford,Neil J. Gemmell,Nicolas Dussex,Nicolas Dussex,Henrik Mouritsen,Nadine Thiele,Kira E. Delmore,Kira E. Delmore,Miriam Liedvogel,Andre Franke,Marc P. Hoeppner,Oliver Krone,Adam M. Fudickar,Borja Milá,Ellen D. Ketterson,Andrew E. Fidler,Guillermo Friis,Ángela M. Parody-Merino,Phil F. Battley,Murray P. Cox,Nicholas Costa Barroso Lima,Francisco Prosdocimi,Thomas L. Parchman,Barney A. Schlinger,Bette A. Loiselle,John G. Blake,Haw Chuan Lim,Haw Chuan Lim,Lainy B. Day,Matthew J. Fuxjager,Maude W. Baldwin,Michael J. Braun,Morgan Wirthlin,Rebecca B. Dikow,T. Brandt Ryder,Glauco Camenisch,Lukas F. Keller,Jeffrey M. DaCosta,Mark E. Hauber,Matthew I. M. Louder,Christopher C. Witt,Jimmy A. McGuire,Joann Mudge,Libby C. Megna,Matthew D. Carling,Biao Wang,Scott A. Taylor,Glaucia Del-Rio,Alexandre Aleixo,Ana Tereza Ribeiro de Vasconcelos,Claudio V. Mello,Jason T. Weir,Jason T. Weir,David Haussler,David Haussler,Qiye Li,Huanming Yang,Jian Wang,Fumin Lei,Carsten Rahbek,M. Thomas P. Gilbert,M. Thomas P. Gilbert,Gary R. Graves,Gary R. Graves,Erich D. Jarvis,Erich D. Jarvis,Erich D. Jarvis,Benedict Paten,Benedict Paten,Guojie Zhang +169 more
TL;DR: The densely sampled alignment provides a single-base-pair map of selection, has more than doubled the fraction of bases that are confidently predicted to be under conservation and reveals extensive patterns of weak selection in predominantly non-coding DNA.
Journal ArticleDOI
An improved canine genome and a comprehensive catalogue of coding genes and non-coding transcripts.
Marc P. Hoeppner,Andrew L. Lundquist,Andrew L. Lundquist,Mono Pirun,Jennifer R. S. Meadows,Neda Zamani,Jeremy Johnson,Görel Sundström,April Cook,Michael Fitzgerald,Ross Swofford,Evan Mauceli,Behrooz Torabi Moghadam,Anna Greka,Jessica Alföldi,Amr Abouelleil,Lynne Aftuck,Daniel Bessette,Aaron M. Berlin,Adam Brown,Gary Gearin,Annie Lui,Pendexter Macdonald,Margaret Priest,Terrance Shea,Jason Turner-Maier,Andrew Zimmer,Eric S. Lander,Federica Di Palma,Federica Di Palma,Kerstin Lindblad-Toh,Kerstin Lindblad-Toh,Manfred Grabherr,Manfred Grabherr +33 more
TL;DR: An improved genome build, canFam3.1, is presented and a much-improved annotation of the canine genome is provided and regulatory functions for several of the novel non-coding transcripts are suggested.
Journal ArticleDOI
Specificity of the innate immune system and diversity of C-type lectin domain (CTLD) proteins in the nematode Caenorhabditis elegans.
TL;DR: High potential for immune specificity in C. elegans is revealed that may enhance the nematode's ability to fight off pathogens and many of which show a pathogen-specific response during infection.