J
Jennifer Picarsic
Researcher at University of Pittsburgh
Publications - 38
Citations - 2647
Jennifer Picarsic is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Langerhans cell histiocytosis & Histiocyte. The author has an hindex of 13, co-authored 32 publications receiving 1405 citations. Previous affiliations of Jennifer Picarsic include Boston Children's Hospital & Cincinnati Children's Hospital Medical Center.
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Journal ArticleDOI
Revised classification of histiocytoses and neoplasms of the macrophage-dendritic cell lineages.
Jean-François Emile,Oussama Abla,Sylvie Fraitag,AnnaCarin Horne,Julien Haroche,Jean Donadieu,Luis Requena-Caballero,Michael B. Jordan,Omar Abdel-Wahab,Carl E. Allen,Frédéric Charlotte,Eli L. Diamond,R. Maarten Egeler,Alain Fischer,Alain Fischer,Juana Gil Herrera,Jan-Inge Henter,Filip Janku,Miriam Merad,Jennifer Picarsic,Carlos Rodriguez-Galindo,Barret J. Rollins,Barret J. Rollins,Abdellatif Tazi,Robert Vassallo,Lawrence M. Weiss +25 more
TL;DR: This revised classification system consists of 5 groups of diseases: (1) Langerhans-related, (2) cutaneous and mucocutaneous, and (3) malignant histiocytoses as well as (4) Rosai-Dorfman disease and (5) hemophagocytic lymphohistiocyts and macrophage activation syndrome.
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The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Myeloid and Histiocytic/Dendritic Neoplasms
Joseph D. Khoury,Eric Solary,Oussama Abla,Yassmine Akkari,Rita Alaggio,Jane F. Apperley,Rafael Bejar,Emilio Berti,Lambert Busque,John K.C. Chan,Weina Chen,Xi Chen,Wee Joo Chng,John K. Choi,Isabel Colmenero,Sarah E. Coupland,Nicholas C.P. Cross,Daphne de Jong,M. Tarek Elghetany,Emiko Takahashi,Jean-François Emile,Judith A. Ferry,Linda Fogelstrand,Michaela Fontenay,Ulrich Germing,Sumeet Gujral,Torsten Haferlach,Claire N. Harrison,Jennelle C. Hodge,Shimin Hu,Joop H. Jansen,Rashmi Kanagal-Shamanna,Hagop M. Kantarjian,Christian P. Kratz,Xiao-Qiu Li,Megan S. Lim,Keith R. Loeb,Sanam Loghavi,Andrea N. Marcogliese,Soheil Meshinchi,Phillip Michaels,Kikkeri N. Naresh,Yasodha Natkunam,Reza Nejati,German Ott,Eric Padron,Keyur Patel,Nikhil Patkar,Jennifer Picarsic,Uwe Platzbecker,Irene Roberts,Anna Schuh,William C. Sewell,Reiner Siebert,Prashant Tembhare,Jeffrey W. Tyner,Srdan Verstovsek,Wei Wang,Brent L. Wood,W Q Xiao,Cecilia Yeung,Andreas Hochhaus +61 more
TL;DR: The 5th edition of the World Health Organization (WHO) Classification of Haematolymphoid Tumours is part of an effort to hierarchically catalogue human cancers arising in various organ systems within a single relational database as discussed by the authors .
Journal ArticleDOI
Consensus recommendations for the diagnosis and clinical management of Rosai-Dorfman-Destombes disease
Oussama Abla,Eric D. Jacobsen,Jennifer Picarsic,Zdenka Krenova,Ronald Jaffe,Jean-François Emile,Benjamin H. Durham,Jorge Braier,Frédéric Charlotte,Jean Donadieu,Fleur Cohen-Aubart,Carlos Rodriguez-Galindo,Carl E. Allen,Carl E. Allen,James A. Whitlock,Sheila Weitzman,Kenneth L. McClain,Julien Haroche,Eli L. Diamond,Eli L. Diamond +19 more
TL;DR: These recommendations include guidelines for clinical, laboratory, pathologic, and radiographic evaluation of patients with RDD together with treatment recommendations based on clinical experience and review of the literature.
Journal ArticleDOI
Mutations in the nuclear bile acid receptor FXR cause progressive familial intrahepatic cholestasis
Natalia Gomez-Ospina,Carol J. Potter,Rui Xiao,Kandamurugu Manickam,Mi Sun Kim,Kang Ho Kim,Benjamin L. Shneider,Jennifer Picarsic,Theodora Jacobson,Jing Zhang,Weimin He,Pengfei Liu,A. S. Knisely,Milton J. Finegold,Donna M. Muzny,Eric Boerwinkle,James R. Lupski,Sharon E. Plon,Richard A. Gibbs,Christine M. Eng,Yaping Yang,Gabriel C. Washington,Matthew H. Porteus,William E. Berquist,Neeraja Kambham,Ravinder J. Singh,Fan Xia,Gregory M. Enns,David D. Moore +28 more
TL;DR: Four individuals from two unrelated families with neonatal cholestasis and mutations in NR1H4, which encodes the farnesoid X receptor (FXR), a bile acid-activated nuclear hormone receptor that regulates bile acids metabolism are reported, demonstrating a pivotal function for FXR in bile Acid homeostasis and liver protection.
Journal ArticleDOI
Molecular Characterization of Sporadic Pediatric Thyroid Carcinoma with the DNA/RNA ThyroSeq v2 Next-Generation Sequencing Assay
Jennifer Picarsic,Melissa Buryk,John A. Ozolek,Sarangarajan Ranganathan,Sara E. Monaco,Jeffrey P. Simons,Selma F. Witchel,Nursen Gurtunca,Judith M. Joyce,Shan Zhong,Marina N. Nikiforova,Yuri E. Nikiforov +11 more
TL;DR: The data support the use of broad gene panels for the molecular diagnostics of pediatric thyroid nodules to aid future classification, treatment, and clinical management recommendations, and additional work is needed to investigate if pediatric DTCs could benefit from a reclassification based on molecular subtypes, which may better reflect their underlying biologic potential.