J
Jin-Wen Song
Researcher at Chinese PLA General Hospital
Publications - 60
Citations - 10333
Jin-Wen Song is an academic researcher from Chinese PLA General Hospital. The author has contributed to research in topics: Medicine & Immune system. The author has an hindex of 13, co-authored 40 publications receiving 7018 citations. Previous affiliations of Jin-Wen Song include Academy of Military Medical Sciences.
Papers
More filters
Journal ArticleDOI
Pathological findings of COVID-19 associated with acute respiratory distress syndrome.
Zhe Xu,Lei Shi,Yijin Wang,Ji-Yuan Zhang,Lei Huang,Chao Zhang,Shuhong Liu,Peng Zhao,Hongxia Liu,Li Zhu,Yanhong Tai,Changqing Bai,Tingting Gao,Jin-Wen Song,Peng Xia,Jing-Hui Dong,Jingmin Zhao,Fu-Sheng Wang +17 more
TL;DR: O surto do novo coronavÃrus (COVID-19) em Wuhan, China, iniciado em dezembro de 2019, evoluiu para se tornar uma pandemia global A.
Journal ArticleDOI
A human neutralizing antibody targets the receptor-binding site of SARS-CoV-2.
Rui Shi,Chao Shan,Xiaomin Duan,Zhihai Chen,Peipei Liu,Jin-Wen Song,Tao Song,Tao Song,Xiaoshan Bi,Xiaoshan Bi,Chao Han,Lianao Wu,Lianao Wu,Ge Gao,Xue Hu,Ya-Nan Zhang,Zhou Tong,Weijin Huang,William J. Liu,Guizhen Wu,Bo Zhang,Lan Wang,Jianxun Qi,Hui Feng,Fu-Sheng Wang,Qihui Wang,George F. Gao,Zhiming Yuan,Jinghua Yan +28 more
TL;DR: Two monoclonal antibodies isolated from a patient with COVID-19 are shown to interfere with SARS-CoV-2–receptor binding, and one displays potent action against this virus in vitro and in a rhesus macaque model.
Journal ArticleDOI
Single-cell landscape of immunological responses in patients with COVID-19.
Ji Yuan Zhang,Xiang Ming Wang,Xudong Xing,Zhe Xu,Chao Zhang,Jin-Wen Song,Xing Fan,Peng Xia,Jun Liang Fu,Si Yu Wang,Ruo Nan Xu,Xiao Peng Dai,Lei Shi,Lei Huang,Tian Jun Jiang,Ming Shi,Yuxia Zhang,Alimuddin Zumla,Alimuddin Zumla,Markus Maeurer,Fan Bai,Fu-Sheng Wang +21 more
TL;DR: The single-cell transcriptional landscape of moderate, severe and convalescent cases of patients with COVID-19 describes the dynamic nature of immune responses during disease progression, and shows a deranged interferon response, profound immune exhaustion with skewed T cell receptor repertoire and broad T cell expansion.
Journal ArticleDOI
Omics-Driven Systems Interrogation of Metabolic Dysregulation in COVID-19 Pathogenesis.
Jin-Wen Song,Sin Man Lam,Xing Fan,Wen-Jing Cao,Si Yu Wang,He Tian,Gek Huey Chua,Chao Zhang,Fan Ping Meng,Zhe Xu,Jun Liang Fu,Lei Huang,Peng Xia,Tao Yang,Shaohua Zhang,Bowen Li,Tian Jun Jiang,Raoxu Wang,Zehua Wang,Ming Shi,Ji Yuan Zhang,Fu-Sheng Wang,Guanghou Shui +22 more
TL;DR: It is suggested that GM3-enriched exosomes may partake in pathological processes related to COVID-19 pathogenesis, and the largest repository on the plasma lipidome and metabolome distinct to CO VID-19 is presented.
Journal ArticleDOI
Immunological and inflammatory profiles in mild and severe cases of COVID-19.
Jin-Wen Song,Chao Zhang,Xing Fan,Fan Ping Meng,Zhe Xu,Peng Xia,Wen-Jing Cao,Wen-Jing Cao,Tao Yang,Xiao Peng Dai,Si Yu Wang,Ruo Nan Xu,Tian Jun Jiang,Wen Gang Li,Dawei Zhang,Peng Zhao,Ming Shi,Chiara Agrati,Giuseppe Ippolito,Markus Maeurer,Alimuddin Zumla,Fu-Sheng Wang,Ji Yuan Zhang +22 more
TL;DR: A higher degree of lymphopenia in various immune cell subsets as well as cytotoxicity and T cell inhibitory marker expression in severe cases compared with mild, indicate that immune-based targets for therapeutic interventions constitute a promising treatment for severe COVID-19 patients.