J
John G.F. Cleland
Researcher at National Institutes of Health
Publications - 1276
Citations - 125527
John G.F. Cleland is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Heart failure & Ejection fraction. The author has an hindex of 137, co-authored 1172 publications receiving 110227 citations. Previous affiliations of John G.F. Cleland include Northwestern University & Imperial College London.
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Journal ArticleDOI
A network analysis to compare biomarker profiles in patients with and without diabetes mellitus in acute heart failure
Abhinav Sharma,Abhinav Sharma,Biniyam G. Demissei,Jasper Tromp,Hans L. Hillege,John G.F. Cleland,Christopher M. O'Connor,Marco Metra,Piotr Ponikowski,John R. Teerlink,Beth A. Davison,Michael M. Givertz,Daniel M. Bloomfield,Howard C. Dittrich,Dirk J. van Veldhuisen,Gad Cotter,Justin A. Ezekowitz,Mohsin A.F. Khan,Adriaan A. Voors +18 more
TL;DR: It is unclear whether distinct pathophysiological processes are present among patients with acute heart failure, with and without diabetes, and network analysis of biomarkers may identify correlative associations that reflect different pathophysiology pathways.
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Clinical trials update from the European Society of Cardiology Meeting 2009: AAA, RELY, PROTECT, ACTIVE-I, European CRT survey, German pre-SCD II registry, and MADIT-CRT
TL;DR: This article provides information and a commentary on trials relevant to the pathophysiology, prevention, and treatment of heart failure presented at the annual meeting of the European Society of Cardiology held in Barcelona in 2009.
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Plasma atrial natriuretic peptide concentrations during exercise in sodium replete and deplete normal man.
A. M. Richards,G. Tonolo,John G.F. Cleland,G. D. Mcintyre,Brenda J. Leckie,Henry J. Dargie,S.G. Ball,J. I. S. Robertson +7 more
TL;DR: Plasma peptide responses were attenuated by sodium depletion with peak exercise levels only double baseline values, in contrast to the threefold increase in ANP concentrations observed when subjects were sodium replete.
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The effects of short-term omission of daily medication on the pathophysiology of heart failure.
Silviu Dovancescu,Silviu Dovancescu,Silviu Dovancescu,Pierpaolo Pellicori,Thato Mabote,Azam Torabi,Andrew L. Clark,John G.F. Cleland,John G.F. Cleland +8 more
TL;DR: The effect of planned HF medication omission for 48 h on weight, echocardiograms, transthoracic bio‐impedance, and plasma concentrations of NT‐proBNP is examined.
Journal ArticleDOI
Impaired Pulmonary Diffusion During Exercise in Patients With Chronic Heart Failure
Alan A. Smith,Peter J. Cowburn,Matthew E. Parker,Martin A. Denvir,Sundeep Puri,Kanti R. Patel,John G.F. Cleland +6 more
TL;DR: The TLCO/Q(C) ratio is consistently impaired in patients with chronic heart failure and relates to both exercise hyperpnea and peak exercise oxygen consumption.