J
John G.F. Cleland
Researcher at National Institutes of Health
Publications - 1276
Citations - 125527
John G.F. Cleland is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Heart failure & Ejection fraction. The author has an hindex of 137, co-authored 1172 publications receiving 110227 citations. Previous affiliations of John G.F. Cleland include Northwestern University & Imperial College London.
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Journal ArticleDOI
MicroRNAs relate to early worsening of renal function in patients with acute heart failure
Noemi Bruno,Jozine M. ter Maaten,Ekaterina S. Ovchinnikova,Eline L. Vegter,Mattia A.E. Valente,Peter van der Meer,Rudolf A. de Boer,Pim van der Harst,Daniela Schmitter,Marco Metra,Christopher M. O'Connor,Piotr Ponikowski,John R. Teerlink,Gad Cotter,Beth A. Davison,John G.F. Cleland,Michael M. Givertz,Daniel M. Bloomfield,Howard C. Dittrich,Yigal M. Pinto,Dirk J. van Veldhuisen,Hans L. Hillege,Eugene Berezikov,Adriaan A. Voors +23 more
TL;DR: The results show that the levels of circulating miRNAs at hospital admission for acute HF were consistently lower in patients who developed worsening of renal function, and MiR-199a-3p was the best predictor of WRF in these patients.
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The year in cardiology 2018: heart failure.
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Is aspirin useful in primary prevention
TL;DR: There is no evidence that aspirin is effective for the primary prevention of cardiovascular events, although it may change the way that they present, and there is noevidence that long-term aspirin should be given to patients even with known cardiovascular disease.
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Heart failure due to ischaemic heart disease: epidemiology, pathophysiology and progression.
John G.F. Cleland,James McGowan +1 more
TL;DR: There are major theoretical and practical concerns about the use of anti-coagulant, anti-platelet and statin therapy in patients with heart failure as well as major theoretical benefits but trials addressing all these areas are under way, which should put the management of coronary disease in patientsWith heart failure on a firm evidence-based footing.
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Cardioreparation and the concept of modulating cardiovascular structure and function.
Karl T. Weber,Christian G. Brilla,John G.F. Cleland,Jay N. Cohn,Lennart Hansson,Anthony M. Heagerty,John H. Laragh,Stéphane Laurent,Jean Pierre Ollivier,Paolo Pauletto,H. Pouleur,Jos F.M. Smits,Lip Bun Tan +12 more
TL;DR: Experimental and clinical trials which address the premise that the structurally remodelled heart and vasculature can be restored to, or toward, normal structure and function by suitable therapy are reviewed.