J
John G.F. Cleland
Researcher at National Institutes of Health
Publications - 1276
Citations - 125527
John G.F. Cleland is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Heart failure & Ejection fraction. The author has an hindex of 137, co-authored 1172 publications receiving 110227 citations. Previous affiliations of John G.F. Cleland include Northwestern University & Imperial College London.
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Clinical trials update from the European Society of Cardiology: SENIORS, ACES, PROVE-IT, ACTION, and the HF-ACTION trial.
TL;DR: The SENIORS trial suggests that nebivolol is well tolerated and effective in older patients with heart failure, even if left ventricular systolic function is not markedly depressed, however, patients aged >75 years appeared to gain less benefit.
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Use of diuretics and outcomes in patients with type 2 diabetes: findings from the EMPA-REG OUTCOME trial
Pierpaolo Pellicori,David Fitchett,Mikhail Kosiborod,Anne Pernille Ofstad,Leo Seman,Bernard Zinman,Isabella Zwiener,Christoph Wanner,Jyothis T. George,Silvio E. Inzucchi,Jeffrey M. Testani,John G.F. Cleland +11 more
TL;DR: In this paper, the authors studied the relationship between heart failure diagnosis, use of loop diuretics, and outcomes in patients with type 2 diabetes mellitus (T2DM) enrolled in the EMPA-REG OUTCOME trial.
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Independent academic Data Monitoring Committees for clinical trials in cardiovascular and cardiometabolic diseases
Gerasimos Filippatos,Pieter A. de Graeff,Jeroen J. Bax,John Joseph Borg,John G.F. Cleland,Henry J. Dargie,Marcus Flather,Ian Ford,Tim Friede,Barry H. Greenberg,Cécile Henon-Goburdhun,Richard Holcomb,Bradley Horst,John Lekakis,Guenther Mueller-Velten,Athanasios G. Papavassiliou,Krishna Prasad,Giuseppe M.C. Rosano,Thomas Severin,Warren Sherman,Wendy Gattis Stough,Karl Swedberg,Luigi Tavazzi,Dimitris Tousoulis,Panagiotis Vardas,Frank Ruschitzka,Stefan D. Anker +26 more
TL;DR: The main recommendations from the meeting relate to methodological consistency, independence, managing conflicts of interest, liability protection, and training of future DMC members.
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Clinical trials update from the American College of Cardiology 2008: Carisma, Trends, meta-analysis of Cox-2 studies, Hat, on-Target, Hyvet, Accomplish, Momentum, Protect, Horizon-hf and Reverse
John G.F. Cleland,Alison P. Coletta,Ashraf Yassin,Hussien Hado,Damien Cullington,Ahmed Tageldien Abdellah,Andrew L. Clark +6 more
TL;DR: This article provides information and a commentary on trials relevant to the pathophysiology, prevention and treatment of heart failure, presented at the American College of Cardiology.
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Coronary angiography in worsening heart failure: determinants, findings and prognostic implications.
João Pedro Ferreira,João Pedro Ferreira,Patrick Rossignol,Biniyam G. Demissei,Abhinav Sharma,Abhinav Sharma,Nicolas Girerd,Stefan D. Anker,John G.F. Cleland,Kenneth Dickstein,Kenneth Dickstein,Gerasimos Filippatos,Hans L. Hillege,Chim C. Lang,Marco Metra,Leong L. Ng,Leong L. Ng,Piotr Ponikowski,N J Samani,Dirk J. van Veldhuisen,Aeilko H. Zwinderman,Adriaan A. Voors,Faiez Zannad +22 more
TL;DR: Coronary angiography was performed in <13% of patients with symptoms and/or signs of worsening HF, and these patients were remarkably different from those who did not undergo coronaryAngiography and had a lower risk of subsequent events.