J
John G.F. Cleland
Researcher at National Institutes of Health
Publications - 1276
Citations - 125527
John G.F. Cleland is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Heart failure & Ejection fraction. The author has an hindex of 137, co-authored 1172 publications receiving 110227 citations. Previous affiliations of John G.F. Cleland include Northwestern University & Imperial College London.
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Journal ArticleDOI
Poor relationship between exercise capacity and spirometric measurements in patients with more symptomatic heart failure
TL;DR: As symptoms worsen, the influence of spirometric variables on peak exercise capacity diminishes, and there is no such relation in the NYHA class III-IV patients.
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Device therapy: Defibrillators-a shocking therapy for cardiomyopathy?
John G.F. Cleland,Laszlo Buga +1 more
TL;DR: Conservative programming of devices may reduce the risks of shocks, thereby increasing morbidity and mortality and detracting from the benefits of this therapy.
Journal ArticleDOI
Genetic Architecture of Acute Myocarditis and the Overlap With Inherited Cardiomyopathy
Amrit Lota,Mark R. Hazebroek,Pantazis I. Theotokis,Rebecca Wassall,Sara Salmi,Brian P Halliday,Upasana Tayal,Job Verdonschot,Devendra Meena,Ruth Owen,Antonio de Marvao,Alma O. Iacob,Momina F Yazdani,Daniel Hammersley,Richard G. Jones,Ricardo Wage,Rachel Buchan,Fredrik Vivian,Yakeen Hafouda,Michela Noseda,John Gregson,Tarun Mittal,Joyce Wong,Jan-Lukas Robertus,AJohn Baksi,Vasos Vassiliou,Ioanna Tzoulaki,Antonis Pantazis,John G.F. Cleland,Paul J.R. Barton,Stuart A. Cook,Dudley J. Pennell,Pablo García-Pavía,Leslie T. Cooper,Stephane Heymans,James S. Ware,Sanjay K Prasad +36 more
TL;DR: Genetic counseling and testing should be considered in patients with acute myocarditis to help reassure the majority while improving the management of those with an underlying genetic variant, including DCM- or ACM-associated genetic variants.
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Exploring quality of life in patients with and without heart failure
Jufen Zhang,James Hobkirk,Sean Carroll,Pierpaolo Pellicori,Andrew L. Clark,John G.F. Cleland +5 more
TL;DR: EHFSQ-1, comprises seven symptom clusters in patients with HF, and either summary factors or QoL scores can be used as an outcome measure, however, if the key question is 'what is this patient'sQoL?' rather than the reason why it is impaired, then a single, direct question may suffice.
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Clinical trials update from the American College of Cardiology: Darbepoetin alfa, ASTEROID, UNIVERSE, paediatric carvedilol, UNLOAD and ICELAND.
TL;DR: This article provides information and a commentary on trials relevant to the pathophysiology, prevention and treatment of heart failure, presented at the American College of Cardiology 55th Annual Scientific Session held in March 2006.