John G.F. Cleland

TL;DR: In this paper, the authors defined the normal range of BUN/creatinine ratio and investigated its clinical significance in patients with acute heart failure (AHF) and found that higher than normal range is associated with worse prognosis independently from both creatinine and BUN.

TL;DR: Interventricular dyssynchrony appears to be an independent characteristic of patients with advanced HF, and is poorly related to clinical, electrocardiographic or standard echocardiographic variable.

TL;DR: A further possibility is that heart failure in patients with diastolic dysfunction might be paroxysmal rather than chronic, and this group of patients may present predominantly to acute units like accident and emergency, coronary care units and intensive Care units and are, therefore, unlikely to figure prominently in the usual outpatient population of chronic systolic left ventricular dysfunction.

TL;DR: Rolofylline treatment was associated with an increased seizure rate, an anticipated complication of A1-receptor antagonists, which underscores the value of longer follow-up durations for AEs, even for agents with short treatment periods, such as in acute heart failure.

TL;DR: In patients with CHF, a raised plasma hsCRP is associated with more congestion and a worse prognosis, and the proportion of deaths that are non-CV also increases with higher hs CRP.