Josef Jampilek

TL;DR: The correlation between RP-HPLC retention parameter log K (the logarithm of capacity factor K) and various calculated log P data is shown and the relationships between the lipophilicity and the chemical structure of the studied compounds are discussed as well.

TL;DR: Heteroatoms constitute a very common fragment of a number of active pharmaceutical ingredients as well as excipients; from the point of view of significance, it is all the same if these are isosterically/bioisosterically replaced carbons/carbon substructures in aliphatic structures or real heterocycles.

TL;DR: Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes is a series of Editorials published on a biannual basis by the Editorial Board of the Medicinal chemistry section of the journal Molecules.

TL;DR: The structure-activity relationships (SAR) between the chemical structure and biological effects of the synthesized compounds are described and the relationships between the RP-HPLC retention parameter logK (the logarithm of capacity factor K) and logP data calculated by available programs are illustrated.

TL;DR: This contribution comprehensively summarizes the current state of the research focused on nanoformulated human and veterinary dietary supplements, nutraceuticals, and functional foods for special medical purposes, their particular applications in various food products and drinks as well as the most important related guidelines, regulations and directives.