J
Jürg Bähler
Researcher at University College London
Publications - 237
Citations - 24955
Jürg Bähler is an academic researcher from University College London. The author has contributed to research in topics: Schizosaccharomyces pombe & Gene. The author has an hindex of 67, co-authored 227 publications receiving 21327 citations. Previous affiliations of Jürg Bähler include University of Debrecen & European Bioinformatics Institute.
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Journal Article
Tuning gene expression to changing environments: from rapid responses to evolutionary adaptation (vol 9, pg 583, 2008)
Journal Article
The Nuclear Poly(A)-Binding Protein Interacts with the Exosome to Promote Synthesis of Noncoding Small Nucleolar RNAs (vol 37, pg 34, 2010)
Jean-François Lemay,Annie D'Amours,Caroline Lemieux,Daniel H. Lackner,Valérie Grenier St-Sauveur,Jürg Bähler,François Bachand +6 more
TL;DR: It is reported that Pab2 functions in the synthesis of noncoding RNAs, contrary to the notion that PABPs function exclusively on protein-coding mRNAs, and exosome recruitment to polyadenylated RNAs is provided.
Journal ArticleDOI
The RNA exosome promotes transcription termination of backtracked RNA polymerase II
Jean-François Lemay,Marc Larochelle,Samuel Marguerat,Sophie R. Atkinson,Jürg Bähler,François Bachand +5 more
TL;DR: The data support a mechanism by which RNAPII backtracking provides a free RNA 3′ end for the core exosome, which results in transcription termination with concomitant degradation of the associated transcript, uncovering a mechanism of cotranscriptional RNA surveillance.
Journal ArticleDOI
Fission yeast Pom1p kinase activity is cell cycle regulated and essential for cellular symmetry during growth and division
Jürg Bähler,Paul Nurse +1 more
TL;DR: It is shown that Pom1p kinase activity is cell cycle regulated in correlation with the state of cellular symmetry: the activity is high during symmetrical growth and division, but lower when cells grow at just one end, and there may be related roles of homologous protein kinases ubiquitously present in all eukaryotes.
Journal ArticleDOI
Exploring long non-coding RNAs through sequencing.
TL;DR: This review discusses how sequencing-based studies are providing global insights into lncRNA transcription, post-transcriptional processing, expression regulation and sites of function.