J
Jürg Bähler
Researcher at University College London
Publications - 237
Citations - 24955
Jürg Bähler is an academic researcher from University College London. The author has contributed to research in topics: Schizosaccharomyces pombe & Gene. The author has an hindex of 67, co-authored 227 publications receiving 21327 citations. Previous affiliations of Jürg Bähler include University of Debrecen & European Bioinformatics Institute.
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Journal ArticleDOI
The copper transport-associated protein Ctr4 can form prion-like epigenetic determinants in Schizosaccharomyces pombe.
Theodora C. Sideri,Yoko Yashiroda,David A. Ellis,María Rodríguez-López,Minoru Yoshida,Mick F. Tuite,Jürg Bähler +6 more
TL;DR: It is shown that S. pombe cells can support the formation and maintenance of the prion form of the S. cerevisiae Sup35 translation factor [PSI+], and that the formationand propagation of these Sup35 aggregates is inhibited by guanidine hydrochloride, indicating commonalities in prion propagation machineries in these evolutionary diverged yeasts.
Journal ArticleDOI
Identification of New Players in Cell Division, DNA Damage Response, and Morphogenesis Through Construction of Schizosaccharomyces pombe Deletion Strains
Jun-Song Chen,Janel R. Beckley,Nathan A. McDonald,Liping Ren,MariaSanta C. Mangione,Sylvia J Jang,Zachary C. Elmore,Nicole Rachfall,Anna Feoktistova,Christine M. Jones,Alaina H. Willet,Rodrigo X. Guillen,Danny A. Bitton,Jürg Bähler,Michael A. Jensen,Nicholas Rhind,Kathleen L. Gould +16 more
TL;DR: This work reports the construction of a set of 281 haploid gene deletion strains covering many previously uncharacterized genes in S. pombe, identifying new genes involved in DNA metabolism, completion of the cell cycle, and morphogenesis.
Journal ArticleDOI
Fission Yeast CSL Transcription Factors: Mapping Their Target Genes and Biological Roles.
Martin Převorovský,Martina Oravcová,Jarmila Tvarůžková,Róbert Zach,Petr Folk,František Půta,Jürg Bähler +6 more
TL;DR: The results provide a framework for a more detailed understanding of the role of CSL proteins in the regulation of cell-cycle progression in fission yeast.
Posted ContentDOI
Mitochondrial respiration is required to provide amino acids during fermentative proliferation of fission yeast
TL;DR: It is concluded that respiration supports rapid proliferation in fermenting cells of fission yeast by boosting the supply of Krebs-cycle derived amino acids.
Journal ArticleDOI
Abo1, a conserved bromodomain AAA‐ATPase, maintains global nucleosome occupancy and organisation
Csenge Gal,Heather E. Murton,Lakxmi Subramanian,Alex J Whale,Karen M Moore,Konrad Paszkiewicz,Sandra Codlin,Jürg Bähler,Kevin M. Creamer,Janet F. Partridge,Robin C. Allshire,Nicholas A. Kent,Simon K. Whitehall +12 more
TL;DR: It is suggested that Abo1 provides a histone chaperone function that maintains nucleosome architecture genome‐wide that prevents silencing and causes elevated chromosome mis‐segregation.