J
Jürg Bähler
Researcher at University College London
Publications - 237
Citations - 24955
Jürg Bähler is an academic researcher from University College London. The author has contributed to research in topics: Schizosaccharomyces pombe & Gene. The author has an hindex of 67, co-authored 227 publications receiving 21327 citations. Previous affiliations of Jürg Bähler include University of Debrecen & European Bioinformatics Institute.
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Journal ArticleDOI
Global transcriptional responses of fission yeast to environmental stress
Dongrong Chen,W. Mark Toone,Juan Mata,Rachel Lyne,Gavin Burns,Katja Kivinen,Alvis Brazma,Nic Jones,Jürg Bähler +8 more
TL;DR: Transcriptional responses of the fission yeast Schizosaccharomyces pombe to various environmental stresses were explored and promoter motifs associated with some of the groups of coregulated genes were identified.
Journal ArticleDOI
The BioGRID Interaction Database: 2008 update
Bobby-Joe Breitkreutz,Chris Stark,Teresa Reguly,Lorrie Boucher,Ashton Breitkreutz,Michael S. Livstone,Rose Oughtred,Daniel H. Lackner,Jürg Bähler,Valerie Wood,Kara Dolinski,Mike Tyers +11 more
TL;DR: A number of new features have been added to the BioGRID including an improved user interface to display interactions based on different attributes, a mirror site and a dedicated interaction management system to coordinate curation across different locations.
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Methylation of histone H4 lysine 20 controls recruitment of Crb2 to sites of DNA damage.
TL;DR: It is argued that H4-K20 methylation functions as a "histone mark" required for the recruitment of the checkpoint protein Crb2, a homolog of the mammalian checkpoint protein 53BP1.
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Quantitative Analysis of Fission Yeast Transcriptomes and Proteomes in Proliferating and Quiescent Cells
Samuel Marguerat,M Alexander Schmidt,Sandra Codlin,Wei-Wei Chen,Ruedi Aebersold,Ruedi Aebersold,Jürg Bähler +6 more
TL;DR: This rich resource provides the first comprehensive reference for all RNA and most protein concentrations in a eukaryote under two key physiological conditions: cellular proliferation and quiescence.
Journal ArticleDOI
Periodic gene expression program of the fission yeast cell cycle
Gabriella Rustici,Juan Mata,Katja Kivinen,Pietro Liò,Christopher J. Penkett,Gavin Burns,Jacqueline Hayles,Alvis Brazma,Paul Nurse,Paul Nurse,Jürg Bähler +10 more
TL;DR: The genome-wide transcriptional program of the Schizosaccharomyces pombe cell cycle was studied in this paper, identifying 407 periodically expressed genes of which 136 show high-amplitude changes.