K
Kathryn Beal
Researcher at Wellcome Trust Sanger Institute
Publications - 40
Citations - 28937
Kathryn Beal is an academic researcher from Wellcome Trust Sanger Institute. The author has contributed to research in topics: Genome & Gene. The author has an hindex of 29, co-authored 39 publications receiving 22526 citations. Previous affiliations of Kathryn Beal include Wellcome Trust & European Bioinformatics Institute.
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Journal ArticleDOI
Genome sequence of an Australian kangaroo, Macropus eugenii, provides insight into the evolution of mammalian reproduction and development
Marilyn B. Renfree,Marilyn B. Renfree,Anthony T. Papenfuss,Anthony T. Papenfuss,Anthony T. Papenfuss,Janine E. Deakin,Janine E. Deakin,James Lindsay,Thomas N. Heider,Katherine Belov,Katherine Belov,Willem Rens,Paul D. Waters,Paul D. Waters,Elizabeth A. Pharo,Geoff Shaw,Geoff Shaw,Emily S. W. Wong,Emily S. W. Wong,Christophe Lefevre,Kevin R. Nicholas,Yoko Kuroki,Matthew Wakefield,Matthew Wakefield,Kyall R. Zenger,Kyall R. Zenger,Kyall R. Zenger,Chenwei Wang,Chenwei Wang,Malcolm A. Ferguson-Smith,Frank W. Nicholas,Danielle Hickford,Danielle Hickford,Hongshi Yu,Hongshi Yu,Kirsty R. Short,Hannah V. Siddle,Hannah V. Siddle,Stephen Frankenberg,Stephen Frankenberg,Keng Yih Chew,Keng Yih Chew,Brandon R. Menzies,Brandon R. Menzies,Brandon R. Menzies,Jessica M Stringer,Jessica M Stringer,Shunsuke Suzuki,Shunsuke Suzuki,Timothy A. Hore,Timothy A. Hore,Margaret L. Delbridge,Margaret L. Delbridge,A Mohammadi,A Mohammadi,Nanette Y. Schneider,Nanette Y. Schneider,Yanqiu Hu,Yanqiu Hu,William A O'Hara,Shafagh Al Nadaf,Shafagh Al Nadaf,Chen-Chen Wu,Zhi-Ping Feng,Zhi-Ping Feng,Benjamin G. Cocks,Jianghui Wang,Paul Flicek,Stephen M. J. Searle,Susan Fairley,Kathryn Beal,Javier Herrero,Dawn M. Carone,Dawn M. Carone,Yutaka Suzuki,Sumio Sugano,Atsushi Toyoda,Yoshiyuki Sakaki,Shinji Kondo,Yuichiro Nishida,Shoji Tatsumoto,Ion Mandiou,Arthur Hsu,Arthur Hsu,Kaighin A. McColl,Benjamin James Lansdell,George M. Weinstock,Elizabeth Kuczek,Elizabeth Kuczek,Elizabeth Kuczek,Annette McGrath,Peter A Wilson,A. Men,Mehlika Hazar-Rethinam,Allison Hall,John Davis,David L. A. Wood,Sarah E. Williams,Yogi Sundaravadanam,Donna M. Muzny,Shalini N. Jhangiani,Lora Lewis,Margaret Morgan,Geoffrey Okwuonu,San Juana Ruiz,Jireh Santibanez,Lynne V. Nazareth,Andrew Cree,Gerald R. Fowler,Christie Kovar,Huyen Dinh,Vandita Joshi,Chyn Jing,Fremiet Lara,Rebecca Thornton,Lei Chen,Jixin Deng,Yue-E Liu,Joshua Y Shen,Xing-Zhi Henry Song,Janette Edson,Carmen Troon,Daniel Thomas,Amber E. Stephens,Lankesha Yapa,Tanya Levchenko,Richard A. Gibbs,Desmond W. Cooper,Desmond W. Cooper,Terence P. Speed,Terence P. Speed,Asao Fujiyama,Asao Fujiyama,Jennifer A. Marshall Graves,Jennifer A. Marshall Graves,Rachel J. O’Neill,Andrew J Pask,Andrew J Pask,Andrew J Pask,Susan M. Forrest,Susan M. Forrest,Kim C. Worley +141 more
TL;DR: The genome sequence of the tammar wallaby, Macropus eugenii, is presented, which is a member of the kangaroo family and the first representative of the iconic hopping mammals that symbolize Australia to be sequenced, to provide new insight into marsupial and mammalian biology and genome evolution.
Journal ArticleDOI
The Ensembl REST API: Ensembl Data for Any Language
Andrew D. Yates,Kathryn Beal,Stephen Keenan,William M. McLaren,Miguel Pignatelli,Graham R. S. Ritchie,Magali Ruffier,Kieron Taylor,Alessandro Vullo,Paul Flicek +9 more
TL;DR: A Web service to access Ensembl data using Representational State Transfer (REST) that enables the easy retrieval of a wide range of EnsembL data by most programming languages, using standard formats such as JSON and FASTA while minimizing client work.
Journal ArticleDOI
Alignathon: A competitive assessment of whole genome alignment methods
Dent Earl,Ngan Nguyen,Glenn Hickey,Robert S. Harris,Stephen Fitzgerald,Kathryn Beal,Igor Seledtsov,Vladimir Molodtsov,Brian J. Raney,Hiram Clawson,Jaebum Kim,Carsten Kemena,Carsten Kemena,Jia-Ming Chang,Ionas Erb,Alexander Poliakov,Minmei Hou,Javier Herrero,W. J. Kent,Victor V. Solovyev,Aaron E. Darling,Jian Ma,Cedric Notredame,Michael Brudno,Inna Dubchak,Inna Dubchak,David Haussler,David Haussler,Benedict Paten +28 more
TL;DR: It is found that many tools worked well at shorter evolutionary distances, but fewer performed competitively at longer distances, indicating that there are substantial accuracy differences between contemporary alignment tools.
Journal ArticleDOI
Analysis of variation at transcription factor binding sites in Drosophila and humans
Mikhail Spivakov,Junaid Akhtar,Pouya Kheradpour,Pouya Kheradpour,Kathryn Beal,Charles Girardot,Gautier Koscielny,Javier Herrero,Manolis Kellis,Manolis Kellis,Eileen E. M. Furlong,Ewan Birney +11 more
TL;DR: A metric of TFBS variability is introduced that takes into account changes in motif match associated with mutation and makes it possible to investigate TFBS functional constraints instance-by-instance as well as in sets that share common biological properties.
Journal ArticleDOI
The pig X and Y Chromosomes: structure, sequence, and evolution
Benjamin M. Skinner,Carole A. Sargent,Carol Churcher,Toby Hunt,Javier Herrero,Javier Herrero,Jane E. Loveland,Matthew Dunn,Sandra Louzada,Beiyuan Fu,William Chow,James G. R. Gilbert,Siobhan Austin-Guest,Kathryn Beal,Denise Carvalho-Silva,William Cheng,Daria Gordon,Darren Grafham,Matthew Hardy,Jo Harley,Heidi Hauser,Philip Howden,Philip Howden,Kerstin Howe,Kim Lachani,Peter J.I. Ellis,Daniel Kelly,Giselle Kerry,James Kerwin,Bee Ling Ng,Glen Threadgold,Thomas Wileman,Jonathan Wood,Fengtang Yang,Jen Harrow,Nabeel A. Affara,Chris Tyler-Smith +36 more
TL;DR: This sequencing project has allowed us to identify genes--both single copy and amplified--on the pig Y chromosome, to compare the pig X and Y Chromosomes for homologous sequences, and thereby to reveal mechanisms underlying pig X/Y Chromosome evolution.