K
Klára Hilscherová
Researcher at Masaryk University
Publications - 184
Citations - 8550
Klára Hilscherová is an academic researcher from Masaryk University. The author has contributed to research in topics: Microcystin & Bioassay. The author has an hindex of 46, co-authored 174 publications receiving 7229 citations. Previous affiliations of Klára Hilscherová include University of Veterinary and Pharmaceutical Sciences Brno & United States Fish and Wildlife Service.
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Journal ArticleDOI
Benchmarking Organic Micropollutants in Wastewater, Recycled Water and Drinking Water with In Vitro Bioassays
Beate I. Escher,Mayumi Allinson,Mayumi Allinson,Rolf Altenburger,Peter A. Bain,Patrick Balaguer,Wibke Busch,Jordan Crago,Nancy D. Denslow,Elke Dopp,Klára Hilscherová,Andrew R. Humpage,Anu Kumar,Marina Grimaldi,B. Sumith Jayasinghe,Barbora Jarošová,Ai Jia,Sergei S. Makarov,Keith A. Maruya,Alexander V. Medvedev,Alvine C. Mehinto,Jamie E. Mendez,Anita H. Poulsen,Erik Prochazka,Jessica Richard,Andrea Schifferli,Daniel Schlenk,Stefan Scholz,Fujio Shiraishi,Shane A. Snyder,Guanyong Su,Janet Y. M. Tang,Bart van der Burg,Sander C. van der Linden,Inge Werner,Sandy D. Westerheide,Chris K C Wong,Min Yang,Bonnie H. Y. Yeung,Xiaowei Zhang,Frederic D.L. Leusch +40 more
TL;DR: This study has demonstrated that selected cell-based bioassays are suitable to benchmark water quality and it is recommended to use a purpose-tailored panel of bioassay for routine monitoring.
Journal ArticleDOI
Effect-directed analysis supporting monitoring of aquatic environments - An in-depth overview
Werner Brack,Selim Ait-Aissa,Robert M. Burgess,Wibke Busch,Nicolas Creusot,Carolina Di Paolo,Beate I. Escher,L. Mark Hewitt,Klára Hilscherová,Juliane Hollender,Henner Hollert,Willem Jonker,Jeroen Kool,Marja H. Lamoree,Matthias Muschket,Steffen Neumann,Pawel Rostkowski,Christoph Ruttkies,Jennifer E. Schollée,Emma L. Schymanski,Tobias Schulze,Thomas-Benjamin Seiler,Andrew J. Tindall,Gisela de Aragão Umbuzeiro,Branislav Vrana,Martin Krauss +25 more
TL;DR: Current experience with the EDA approach and the tools required are summarized, and practical advice on their application is provided, highlighting the need for proper problem formulation and giving general advice for study design.
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Towards the review of the European Union Water Framework Directive: Recommendations for more efficient assessment and management of chemical contamination in European surface water resources.
Werner Brack,Werner Brack,Valeria Dulio,Marlene Ågerstrand,Ian Allan,Rolf Altenburger,Markus Brinkmann,Dirk Bunke,Robert M. Burgess,Ian T. Cousins,Beate I. Escher,Félix Hernández,Mark L. Hewitt,Klára Hilscherová,Juliane Hollender,Henner Hollert,Robert Kase,Bernd Klauer,Claudia Lindim,David López Herráez,Cécil Miège,John Munthe,Simon O’Toole,Leo Posthuma,Heinz Rüdel,Ralf B. Schäfer,Manfred Sengl,Foppe Smedes,Dik van de Meent,Paul J. Van den Brink,Jos van Gils,Annemarie P. van Wezel,A. Dick Vethaak,Etiënne L.M. Vermeirssen,Peter C. von der Ohe,Branislav Vrana +35 more
TL;DR: 10 recommendations to improve monitoring and to strengthen comprehensive prioritization, to foster consistent assessment and to support solution-oriented management of surface waters are given.
Journal ArticleDOI
Future water quality monitoring--adapting tools to deal with mixtures of pollutants in water resource management.
Rolf Altenburger,Selim Ait-Aissa,Philipp Antczak,Thomas Backhaus,Damià Barceló,Thomas-Benjamin Seiler,François Brion,Wibke Busch,Kevin Chipman,Miren López de Alda,Gisela de Aragão Umbuzeiro,Beate I. Escher,Francesco Falciani,Michael Faust,Andreas Focks,Klára Hilscherová,Juliane Hollender,Henner Hollert,Felix Jäger,Annika Jahnke,Andreas Kortenkamp,Martin Krauss,Gregory F. Lemkine,John Munthe,Steffen Neumann,Emma L. Schymanski,Mark D. Scrimshaw,Helmut Segner,Jaroslav Slobodnik,Foppe Smedes,Subramaniam Kughathas,Ivana Teodorovic,Andrew J. Tindall,Knut Erik Tollefsen,Karl-Heinz Walz,Tim D. Williams,Paul J. Van den Brink,Jos van Gils,Branislav Vrana,Xiaowei Zhang,Werner Brack +40 more
TL;DR: The vision of the international, EU-funded project SOLUTIONS is described, where three routes are explored to link the occurrence of chemical mixtures at specific sites to the assessment of adverse biological combination effects, and comprehensive arrays of effect-based tools and trait-based field observations are explored.
Journal ArticleDOI
Cell bioassays for detection of aryl hydrocarbon (AhR) and estrogen receptor (ER) mediated activity in environmental samples
TL;DR: In this article, aryl hydrocarbon receptor (AhR)-(hereafter referred as dioxin-like) or estrogen receptor (ER)-mediated activities of potential endocrine disrupting compounds (EDCs) in complex environmental mixtures.