L
L D Blumhardt
Researcher at Queen's University
Publications - 17
Citations - 1322
L D Blumhardt is an academic researcher from Queen's University. The author has contributed to research in topics: Expanded Disability Status Scale & Working memory. The author has an hindex of 14, co-authored 17 publications receiving 1256 citations. Previous affiliations of L D Blumhardt include Icahn School of Medicine at Mount Sinai.
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Journal ArticleDOI
Glatiramer acetate in primary progressive multiple sclerosis: Results of a multinational, multicenter, double-blind, placebo-controlled trial
Jerry S. Wolinsky,Ponnada A. Narayana,Paul O'Connor,P. K. Coyle,Corey C. Ford,Kenneth P. Johnson,Kenneth P. Johnson,Aaron Miller,Aaron Miller,Lillian Pardo,Shaul Kadosh,David Ladkani,Lorne F. Kastrukoff,Pierre Duquette,Mark S. Freedman,Marc Debouverie,Catherine Lubetski,Gilles Edan,E Roullet,Christian Confavreux,Alan J. Thompson,L D Blumhardt,L D Blumhardt,Stanley Hawkins,Thomas F. Scott,Daniel Wynn,Joanna Cooper,Stephen Thurston,Stanton B. Elias,Clyde E. Markowitz,David Mattson,John H. Noseworthy,Elizabeth A. Shuster,Jonathan L. Carter,Fred D. Lublin,WH Stuart,Michael D. Kaufman,Gary Birnbaum,Kottil Rammohan,Ruth H. Whitham,Cornelia Mihai,Steven J. Greenberg,Craig M. Smith,Mark A. Agius,Stan Van Den Noort,Lawrence W. Myers,James G. Nelson,Douglas S. Goodin,Barry G. W. Arnason,Khurram Bashir,Sharon G. Lynch,Patricia K. Coyle,Stephen Kamin,William A. Sheremata,Galen Mitchell,Andrew D. Goodman,Norman J Kachuck,Peter B. Dunne,J. William Lindsey,Elliot M. Frohman,James D. Bowen,Benjamin Rix Brooks,John W. Rose,Harold L. Moses,Douglas Jeffrey,Anne H. Cross,Robert P. Lisak,Timothy Vollmer,Jack P. Antel,Gary Cutter,Luanne M. Metz,Henry F. McFarland,Steven Reingold,Fred D. Lublin,Irina Vainrub,Lucie Lambert,Fengwei Zhong,Jeff Rasmituth,Saria Momin,Rivka Kreitman,Galia Shifroni,Irit Pinchasi,Yafit Stark +82 more
TL;DR: To determine whether glatiramer acetate slows accumulation of disability in primary progressive multiple sclerosis, a new drug is developed that acts as a ‘spatially aggregating agent’ to reduce the risk of disease progression.
Journal ArticleDOI
The clinical and laboratory features of chronic sensory ataxic neuropathy with anti-disialosyl IgM antibodies.
Hugh J. Willison,Colin P. O'Leary,J. Veitch,L D Blumhardt,M Busby,Michael Donaghy,Peter Fuhr,Helen Ford,A Hahn,Susanne Renaud,H A Katifi,S Ponsford,Markus Reuber,Andreas J. Steck,Ian Sutton,W Schady,P. K. Thomas,Alan J. Thompson,J M Vallat,John B Winer +19 more
TL;DR: The clinical and laboratory phenotype of a paraproteinaemic neuropathy syndrome termed chronic sensory ataxic neuropathy with anti-disialosyl IgM antibodies is described in a series of 18 cases, in which clinical electrophysiology and nerve biopsy show both demyelinating and axonal features.
Journal ArticleDOI
Working memory impairment in early multiple sclerosis. Evidence from an event-related potential study of patients with clinically isolated myelopathy.
TL;DR: Objective evidence of subclinical working memory dysfunction in patients at an early stage of demyelinating disease is provided, i.e. when they first present with clinically isolated spinal cord lesions and before they have developed symptoms of cognitive or memory dysfunction.
Journal ArticleDOI
Infratentorial atrophy on magnetic resonance imaging and disability in multiple sclerosis
TL;DR: MRI-estimated structural volumes may provide a simple index of axonal and/or myelin loss, the presumed pathological substrates of irreversible impairment and disability in multiple sclerosis, in patients with relapsing-remitting multiple sclerosis.
Journal ArticleDOI
Cerebral atrophy and disability in relapsing-remitting and secondary progressive multiple sclerosis over four years.
TL;DR: This study demonstrated an association between measures of cerebral atrophy and worsening disability and provides evidence that brain atrophy can be detected early in the disease course and central white matter atrophy as reflected by ventricle enlargement appears to be a continuous process.