L
Laura Wilson
Researcher at Johns Hopkins University
Publications - 35
Citations - 1526
Laura Wilson is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Gastroparesis & Nonalcoholic fatty liver disease. The author has an hindex of 14, co-authored 33 publications receiving 1050 citations. Previous affiliations of Laura Wilson include University of Baltimore.
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Journal ArticleDOI
Portal chronic inflammation in nonalcoholic fatty liver disease (NAFLD): a histologic marker of advanced NAFLD-Clinicopathologic correlations from the nonalcoholic steatohepatitis clinical research network
Elizabeth M. Brunt,David E. Kleiner,Laura Wilson,Aynur Unalp,Cynthia E. Behling,Joel E. Lavine,Brent A. Neuschwander-Tetri,Stephanie H. Abrams,Diana Arceo,Denise Espinosa,Leanel Fairly,Diane Bringman,Carol Hawkins,Yao Chang Liu,Nicholette Rogers,Margaret Stager,Arthur J. McCullough,Srinivasan Dasarathy,Kevin Edwards,Ruth Sargent,Melissa J. Coffey,Karen F. Murray,Melissa Young,Parvathi Mohan,Kavita Nair,Manal F. Abdelmalek,Anna Mae Diehl,Marcia R. Gottfried,Cynthia D. Guy,Paul G. Killenberg,Samantha Kwan,Yi Ping Pan,Dawn Piercy,Melissa Smith,Prajakta Bhimalli,Naga Chalasani,Oscar W. Cummings,Lydia Lee,Linda Ragozzino,Raj Vuppalanchi,Barbara Calabrese,Debra Peglow,Ann O. Scheimann,Michael Torbenson,Ann Klipsch,Jean P. Molleston,Girish Subbarao,Sarah E. Barlow,Jose Derdoy,Joyce Hoffmann,Debra King,Joan Siegner,Susan Stewart,Brent A. Tetri,Judy Thompson,Cynthia Behling,Manual Celedon,Lisa Clark,Janis Durelle,Tarek Hassanein,Susana Mendoza,Jeffrey B. Schwimmer,Claude B. Sirlin,Tanya Stein,Allison Tobin,Kiran Bambha,Nathan M. Bass,Linda D. Ferrell,Danuta Filipowski,Raphael B. Merriman,Mark Pabst,Monique Rosenthal,Philip J. Rosenthal,Tessa Steel,Sherry Boyett,Daphne Bryan,Melissa J. Contos,Michael Fuchs,Martin F. Graham,Amy Jones,Velimir A. Luketic,Bimalijit Sandhu,Arun J. Sanyal,Carol Sargeant,Kimberly Selph,Melanie B. White,Kris V. Kowdley,Grace Gyurkey,Jody Mooney,James E. Nelson,Sarah Roberts,Cheryl Saunders,Alice Stead,Chia Wang,Matthew M. Yeh,Elizabeth M. Brunt,D Kleiner,Gilman D. Grave,Terry T.-K. Huang,Edward Doo,Jay E. Everhart,Jay H. Hoofnagle,Patricia R. Robuck,Leonard B. Seeff,Patricia Belt,Fred Brancati,Jeanne M. Clark,Ryan Colvin,Michel Donithan,Mika Green,Rosemary Hollick,Milana Isaacson,Wana Kim,Alison Lyndecker,Laura Miriel,Alice L. Sternberg,James Tonascia,Aynur Unalp-Arida,Mark L. Van Natta,Laura A. Wilson,Katherine P. Yates +120 more
TL;DR: Increased portal CI is associated with many clinical and pathologic features of progressive NAFLD in both adults and children, but not with ALT, autoantibodies, or lobular inflammation.
Journal ArticleDOI
Association of Histologic Disease Activity With Progression of Nonalcoholic Fatty Liver Disease
David E. Kleiner,Elizabeth M. Brunt,Laura Wilson,Cynthia Behling,Cynthia D. Guy,Melissa J. Contos,Oscar W. Cummings,Matthew M. Yeh,Ryan M. Gill,Naga Chalasani,Brent A. Neuschwander-Tetri,Anna Mae Diehl,Srinivasan Dasarathy,Norah A. Terrault,Kris V. Kowdley,Rohit Loomba,Patricia Belt,James Tonascia,Joel E. Lavine,Arun J. Sanyal +19 more
TL;DR: High baseline nonalcoholic fatty liver disease activity score and changes in the score were associated with concordant changes in fibrosis, and weight gain and an increasing aspartate aminotransferase level should increase suspicion of increasing fibrosis.
Association of Histologic Disease Activity With Progression of Nonalcoholic Fatty Liver Disease
David E. Kleiner,Elizabeth M. Brunt,Laura Wilson,Cynthia Behling,Cynthia D. Guy,Melissa J. Contos,Oscar W. Cummings,Matthew M. Yeh,Ryan M. Gill,Naga Chalasani,Brent A. Neuschwander-Tetri,Anna Mae Diehl,Srinivasan Dasarathy,Norah A. Terrault,Kris V. Kowdley,Rohit Loomba,Patricia Belt,James Tonascia,Joel E. Lavine,Arun J. Sanyal +19 more
TL;DR: In this article, the authors evaluated the histologic evolution of NAFLD and the factors associated with changes in disease severity over time using a prospective cohort substudy from the Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN) database.
Journal ArticleDOI
Diagnostic Accuracy of Noninvasive Fibrosis Models to Detect Change in Fibrosis Stage.
Mohammad S. Siddiqui,Goro Yamada,Raj Vuppalanchi,Mark L. Van Natta,Rohit Loomba,Cynthia D. Guy,Danielle Brandman,James Tonascia,Naga Chalasani,Brent A. Neuschwander-Tetri,Arun J. Sanyal,Daniela S. Allende,Srinivasan Dasarathy,Arthur J. McCullough,Revathi Penumatsa,Jaividhya Dasarathy,Joel E. Lavine,Manal F. Abdelmalek,Mustafa R. Bashir,Stephanie Buie,Anna Mae Diehl,Christopher J. N. Kigongo,Mariko Kopping,David Malik,Dawn Piercy,Oscar W. Cummings,Samer Gawrieh,Linda Ragozzino,Kumar Sandrasegaran,Elizabeth M. Brunt,Theresa Cattoor,Danielle Carpenter,Janet Freebersyser,Debra King,Jinping Lai,Brent A. Neuschwander-Tetri,Joan Siegner,Susan Stewart,Susan Torretta,Kristina Wriston,Maria Cardona Gonzalez,Jodie Davila,Manan Jhaveri,Kris V. Kowdley,Nizar Mukhtar,Erik Ness,Michelle Poitevin,Brook Quist,Sherilynn Soo,Brandon Ang,Cynthia Behling,Archana Bhatt,Michael S. Middleton,Claude B. Sirlin,Maheen F. Akhter,Nathan M. Bass,Ryan M. Gill,Bilal Hameed,Jacqueline Maher,Norah A. Terrault,Ashley Ungermann,Matthew M. Yeh,Sherry Boyett,Melissa J. Contos,Sherri Kirwin,Velimir A. Luketic,Puneet Puri,Jolene Schlosser,Mohammad S. Siddiqui,Leslie Yost-Schomer,Kathryn J. Fowler,David E. Kleiner,Edward Doo,Sherry Hall,Jay H. Hoofnagle,Jessica J. Lee,Patricia R. Robuck,Averell H. Sherker,Rebecca Torrance,Patricia Belt,Jeanne M. Clark,John Dodge,Michele Donithan,Erin Hallinan,Milana Isaacson,Mariana Lazo,Jill Meinert,Laura Miriel,Jacqueline Smith,Mike Smith,Alice L. Sternberg,Mark L. Van Natta,Annette Wagoner,Laura Wilson,Katherine P. Yates +94 more
TL;DR: In a combined analysis of data from 2 large studies, it is found that FIB-4, APRI, and NFS can detect advanced fibrosis and fibrosis progression in patients with NAFLD.
Journal ArticleDOI
Aprepitant Has Mixed Effects on Nausea and Reduces Other Symptoms in Patients With Gastroparesis and Related Disorders
Pankaj J. Pasricha,Katherine P. Yates,Irene Sarosiek,Richard W. McCallum,Thomas L. Abell,Kenneth L. Koch,Linda Anh B. Nguyen,William J. Snape,William L. Hasler,John O. Clarke,Sameer Dhalla,Ellen M. Stein,Linda A. Lee,Laura Miriel,Mark L. Van Natta,Madhusudan Grover,Gianrico Farrugia,James Tonascia,Frank A. Hamilton,Henry P. Parkman,Nata DeVole,Karen Earle,Kjersti Kirkeby,Candice Lee,Mimi Lin,Katie Ponting,Gloria Yee,P. J. Pasricha,Ellen Stein,Yale Kim,Gotzone Garay,Chiara Orlando,Alan Mauer,Perry Orthey,Amiya Palit,Sean Connery,Yvette Gomez,Roberta Romero,Natalia Vega,Ben Alvarado,Lisa Hatter,Ronna Howard,Lindsay Nowotny,William H. Herman,Andrew T. Kraftson,Amy E. Rothberg,Sophanara Wootten,Lynn Baxter,Anya Brown,Paula S. Stuart,Samantha Culler,Cheryl E. Bernard,Frank Hamilton,Jose Serrano,Stephen P. James,Rebecca Torrance,Sherry Hall,Patricia Belt,John Dodge,Michele Donithan,Erin Hallinan,Milana Isaacson,Patrick May,Laura Miriel,Alice L. Sternberg,Mark L. Van Natta,Annette Wagoner,Laura Wilson +67 more
TL;DR: The findings of this randomized trial of the ability of the neurokinin-1 receptor antagonist aprepitant to reduce symptoms in patients with chronic nausea and vomiting caused by gastropareis or gastroparesis-like syndrome support the need to identify appropriate patient outcomes for trials of therapies for gastroparedis.