M
Matthew M. Yeh
Researcher at University of Washington Medical Center
Publications - 57
Citations - 13429
Matthew M. Yeh is an academic researcher from University of Washington Medical Center. The author has contributed to research in topics: Steatohepatitis & Fatty liver. The author has an hindex of 25, co-authored 42 publications receiving 10860 citations. Previous affiliations of Matthew M. Yeh include Virginia Mason Medical Center & Yale University.
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Journal ArticleDOI
Design and validation of a histological scoring system for nonalcoholic fatty liver disease
David E. Kleiner,Elizabeth M. Brunt,Mark L. Van Natta,Cynthia Behling,Melissa J. Contos,Oscar W. Cummings,Linda D. Ferrell,Yao Chang Liu,Michael Torbenson,Aynur Unalp-Arida,Matthew M. Yeh,Arthur J. McCullough,Arun J. Sanyal +12 more
TL;DR: A strong scoring system and NAS for NAFLD and NASH with reasonable inter‐rater reproducibility that should be useful for studies of both adults and children with any degree ofNAFLD are presented.
Journal ArticleDOI
Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma
Adrian Ally,Miruna Balasundaram,Rebecca Carlsen,Eric Chuah,Amanda Clarke,Noreen Dhalla,Robert A. Holt,Steven J.M. Jones,Darlene Lee,Yussanne Ma,Marco A. Marra,Michael Mayo,Richard A. Moore,Andrew J. Mungall,Jacqueline E. Schein,Payal Sipahimalani,Angela Tam,Nina Thiessen,Dorothy Cheung,Tina Wong,Denise Brooks,A. Gordon Robertson,Reanne Bowlby,Karen Mungall,Sara Sadeghi,Liu Xi,Kyle R. Covington,Eve Shinbrot,David A. Wheeler,Richard A. Gibbs,Lawrence A. Donehower,Linghua Wang,Jay Bowen,Julie M. Gastier-Foster,Mark Gerken,Carmen Helsel,Kristen M. Leraas,Tara M. Lichtenberg,Nilsa C. Ramirez,Lisa Wise,Erik Zmuda,Stacey Gabriel,Matthew Meyerson,Carrie Cibulskis,Bradley A. Murray,Juliann Shih,Rameen Beroukhim,Andrew D. Cherniack,Steven E. Schumacher,Gordon Saksena,Chandra Sekhar Pedamallu,Lynda Chin,Gad Getz,Michael S. Noble,Hailei Zhang,David I. Heiman,Juok Cho,Nils Gehlenborg,Douglas Voet,Pei Lin,Scott Frazer,Timothy Defreitas,Sam Meier,Michael S. Lawrence,Jaegil Kim,Chad J. Creighton,Donna M. Muzny,Harshavardhan Doddapaneni,Jianhong Hu,Min Wang,Donna Morton,Viktoriya Korchina,Yi Han,Huyen Dinh,Lora Lewis,Michelle Bellair,Xiuping Liu,Jireh Santibanez,Robert Glenn,Sandra Lee,Walker Hale,Joel S. Parker,Matthew D. Wilkerson,D. Neil Hayes,Sheila Reynolds,Ilya Shmulevich,Wei Zhang,Yuexin Liu,Lisa Iype,Hala Makhlouf,Michael Torbenson,Sanjay Kakar,Matthew M. Yeh,Dhanpat Jain,David E. Kleiner,Renumathy Dhanasekaran,Hashem B. El-Serag,Sun Young Yim,John N. Weinstein,Lopa Mishra,Jianping Zhang,Rehan Akbani,Shiyun Ling,Zhenlin Ju,Xiaoping Su,Apurva M. Hegde,Gordon B. Mills,Yiling Lu,Jian Chen,Ju Seog Lee,Bo Hwa Sohn,Jae-Jun Shim,Pan Tong,Hiroyuki Aburatani,Shogo Yamamoto,Kenji Tatsuno,Wei Li,Zheng Xia,Nicolas Stransky,Eric Seiser,Federico Innocenti,Jianjiong Gao,Ritika Kundra,Hongxin Zhang,Zachary J. Heins,Angelica Ochoa,Chris Sander,Marc Ladanyi,Ronglai Shen,Arshi Arora,Francisco Sanchez-Vega,Nikolaus Schultz,Katayoon Kasaian,Amie Radenbaugh,Karl-Dimiter Bissig,David D. Moore,Yasushi Totoki,Hiromi Nakamura,Tatsuhiro Shibata,Christina Yau,Kiley Graim,Josh Stuart,David Haussler,Betty L. Slagle,Akinyemi I. Ojesina,Panagiotis Katsonis,Amanda Koire,Olivier Lichtarge,Teng-Kuei Hsu,Martin L. Ferguson,John A. Demchok,Ina Felau,Margi Sheth,Roy Tarnuzzer,Zhining Wang,Liming Yang,Jean C. Zenklusen,Jiashan Zhang,Carolyn M. Hutter,Heidi J. Sofia,Roel G.W. Verhaak,Siyuan Zheng,Frederick Lang,Sudha Chudamani,Jia Liu,Laxmi Lolla,Ye Wu,Rashi Naresh,Todd Pihl,Charlie Sun,Yunhu Wan,Christopher C. Benz,Amy H. Perou,Leigh B. Thorne,Lori Boice,Mei Huang,W. Kimryn Rathmell,Houtan Noushmehr,Fabiano Pinto Saggioro,Daniela Pretti da Cunha Tirapelli,Carlos Gilberto Carlotti Junior,Enio David Mente,Orlando de Castro Silva,Felipe Amstalden Trevisan,Koo Jeong Kang,Keun Soo Ahn,Nasra H. Giama,Catherine D. Moser,Thomas J. Giordano,Michelle Vinco,Theodore H. Welling,Daniel Crain,Erin Curley,Johanna Gardner,David Mallery,Scott Morris,Joseph Paulauskis,Robert Penny,Candace Shelton,Troy Shelton,Robin Kate Kelley,Joong-Won Park,Vishal S. Chandan,Lewis R. Roberts,Oliver F. Bathe,Curt H. Hagedorn,J. Todd Auman,Daniel R. O'Brien,Jean-Pierre A. Kocher,Corbin D. Jones,Piotr A. Mieczkowski,Charles M. Perou,Tara Skelly,Donghui Tan,Umadevi Veluvolu,Saianand Balu,Tom Bodenheimer,Alan P. Hoyle,Stuart R. Jefferys,Shaowu Meng,Lisle E. Mose,Yan Shi,Janae V. Simons,Matthew G. Soloway,Jeffrey Roach,Katherine A. Hoadley,Stephen B. Baylin,Hui Shen,Toshinori Hinoue,Moiz S. Bootwalla,David Van Den Berg,Daniel J. Weisenberger,Phillip H. Lai,Andrea Holbrook,Mario Berrios,Peter W. Laird +235 more
TL;DR: Integrative molecular HCC subtyping incorporating unsupervised clustering of five data platforms identified three subtypes, one of which was associated with poorer prognosis in three HCC cohorts and development of a p53 target gene expression signature correlating with poor survival was enabled.
Journal ArticleDOI
Serum ferritin is an independent predictor of histologic severity and advanced fibrosis in patients with nonalcoholic fatty liver disease.
Kris V. Kowdley,Patricia Belt,Laura A. Wilson,Matthew M. Yeh,Brent A. Neuschwander-Tetri,Naga Chalasani,Arun J. Sanyal,James E. Nelson +7 more
TL;DR: It is concluded that SF is useful to identify NAFLD patients at risk for NASH and advanced fibrosis and is an independent predictor of advanced hepatic fibrosis among patients withNAFLD.
Journal ArticleDOI
Portal chronic inflammation in nonalcoholic fatty liver disease (NAFLD): a histologic marker of advanced NAFLD-Clinicopathologic correlations from the nonalcoholic steatohepatitis clinical research network
Elizabeth M. Brunt,David E. Kleiner,Laura Wilson,Aynur Unalp,Cynthia E. Behling,Joel E. Lavine,Brent A. Neuschwander-Tetri,Stephanie H. Abrams,Diana Arceo,Denise Espinosa,Leanel Fairly,Diane Bringman,Carol Hawkins,Yao Chang Liu,Nicholette Rogers,Margaret Stager,Arthur J. McCullough,Srinivasan Dasarathy,Kevin Edwards,Ruth Sargent,Melissa J. Coffey,Karen F. Murray,Melissa Young,Parvathi Mohan,Kavita Nair,Manal F. Abdelmalek,Anna Mae Diehl,Marcia R. Gottfried,Cynthia D. Guy,Paul G. Killenberg,Samantha Kwan,Yi Ping Pan,Dawn Piercy,Melissa Smith,Prajakta Bhimalli,Naga Chalasani,Oscar W. Cummings,Lydia Lee,Linda Ragozzino,Raj Vuppalanchi,Barbara Calabrese,Debra Peglow,Ann O. Scheimann,Michael Torbenson,Ann Klipsch,Jean P. Molleston,Girish Subbarao,Sarah E. Barlow,Jose Derdoy,Joyce Hoffmann,Debra King,Joan Siegner,Susan Stewart,Brent A. Tetri,Judy Thompson,Cynthia Behling,Manual Celedon,Lisa Clark,Janis Durelle,Tarek Hassanein,Susana Mendoza,Jeffrey B. Schwimmer,Claude B. Sirlin,Tanya Stein,Allison Tobin,Kiran Bambha,Nathan M. Bass,Linda D. Ferrell,Danuta Filipowski,Raphael B. Merriman,Mark Pabst,Monique Rosenthal,Philip J. Rosenthal,Tessa Steel,Sherry Boyett,Daphne Bryan,Melissa J. Contos,Michael Fuchs,Martin F. Graham,Amy Jones,Velimir A. Luketic,Bimalijit Sandhu,Arun J. Sanyal,Carol Sargeant,Kimberly Selph,Melanie B. White,Kris V. Kowdley,Grace Gyurkey,Jody Mooney,James E. Nelson,Sarah Roberts,Cheryl Saunders,Alice Stead,Chia Wang,Matthew M. Yeh,Elizabeth M. Brunt,D Kleiner,Gilman D. Grave,Terry T.-K. Huang,Edward Doo,Jay E. Everhart,Jay H. Hoofnagle,Patricia R. Robuck,Leonard B. Seeff,Patricia Belt,Fred Brancati,Jeanne M. Clark,Ryan Colvin,Michel Donithan,Mika Green,Rosemary Hollick,Milana Isaacson,Wana Kim,Alison Lyndecker,Laura Miriel,Alice L. Sternberg,James Tonascia,Aynur Unalp-Arida,Mark L. Van Natta,Laura A. Wilson,Katherine P. Yates +120 more
TL;DR: Increased portal CI is associated with many clinical and pathologic features of progressive NAFLD in both adults and children, but not with ALT, autoantibodies, or lobular inflammation.
Journal ArticleDOI
Animal models of NASH: getting both pathology and metabolic context right.
Claire Z. Larter,Matthew M. Yeh +1 more
TL;DR: The purpose of the present review is to critique the liver pathology and metabolic abnormalities present in currently available animal models of NASH, with particular focus on models described in approximately the last 5 years.