L
Lea K. Davis
Researcher at Vanderbilt University Medical Center
Publications - 192
Citations - 10453
Lea K. Davis is an academic researcher from Vanderbilt University Medical Center. The author has contributed to research in topics: Medicine & Genome-wide association study. The author has an hindex of 34, co-authored 138 publications receiving 7193 citations. Previous affiliations of Lea K. Davis include Meharry Medical College & Semel Institute for Neuroscience and Human Behavior.
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Journal ArticleDOI
Psychiatric Genomics, Phenomics, and Ethics Research In A 270,000-Person Biobank (BioVU)
TL;DR: Results from three recent biobank initiatives including phenotypic, genetic, and ethical, legal and social issues (ELSI) research are described and a phenotyping algorithm for the detection of OCD in the EMR is developed.
Posted ContentDOI
Genetic risk for major depressive disorder and loneliness in gender-specific associations with coronary artery disease
Jessica Dennis,Julia M. Sealock,Rebecca T. Levinson,Eric Farber-Eger,Jacob Franco,Sarah Fong,Peter Straub,Donald Hucks,MacRae F. Linton,Wen-Liang Song,Pierre Fontanillas,Sarah L. Elson,Douglas M. Ruderfer,Abdel Abdellaoui,Abdel Abdellaoui,Sandra Sanchez-Roige,Abraham A Palmer,Dorret I. Boomsma,Nancy J. Cox,Guanhua Chen,Jonathan D. Mosley,Quinn S. Wells,Lea K. Davis +22 more
TL;DR: In this paper, a phenome-wide association study using EHRs spanning 1990 to 2017 from the Vanderbilt University Medical Center biobank, BioVU was conducted to determine the medical morbidity pattern associated with genetic risk factors for major depressive disorder and loneliness, two common psychological traits with adverse health outcomes.
Journal ArticleDOI
Item-Level Genome-Wide Association Study of the Alcohol Use Disorders Identification Test in Three Population-Based Cohorts
Travis T. Mallard,Jeanne E. Savage,Emma C. Johnson,Yuye Huang,Alexis C. Edwards,Jouke J. Hottenga,Andrew D. Grotzinger,Daniel E. Gustavson,Mariela V Jennings,Andrey Anokhin,Danielle M. Dick,Howard J. Edenberg,John R. Kramer,Dongbing Lai,Jacquelyn L. Meyers,Ashwini K. Pandey,Kathryn Paige Harden,Michel G. Nivard,Eco J. C. de Geus,Dorret I. Boomsma,Arpana Agrawal,Lea K. Davis,Toni-Kim Clarke,Abraham A. Palmer,Sandra Sanchez-Roige +24 more
TL;DR: In this paper, the authors proposed a 10-item screen for alcohol use disorders identification test (AUDIT), which has elucidated novel loci for alcohol consumption disorder (AUD).
Posted ContentDOI
Examination of the Shared Genetic Basis of Anorexia Nervosa and Obsessive-Compulsive Disorder
Zeynep Yilmaz,Matthew Halvorsen,Julien Bryois,Dongmei Yu,Laura M. Thornton,Stephanie Zerwas,Nadia Micali,Nadia Micali,Rainald Moessner,Christie L. Burton,Gwyneth Zai,Gwyneth Zai,Lauren Erdman,Martien J H Kas,Martien J H Kas,Paul D. Arnold,Lea K. Davis,James A. Knowles,Gerome Breen,Jeremiah M. Scharf,Gerald Nestadt,Carol A. Mathews,Cynthia M. Bulik,Cynthia M. Bulik,Manuel Mattheisen,Manuel Mattheisen,James J. Crowley,James J. Crowley +27 more
TL;DR: Follow-up analyses revealed that although AN and OCD overlap heavily in their shared risk with other psychiatric phenotypes, the relationship with metabolic and anthropometric traits is markedly stronger for AN than for OCD.
Posted ContentDOI
The medical signature of musicians: A Phenome-wide association study using an Electronic Health Record database.
Maria Niarchou,Maria Niarchou,George T. Lin,Miriam D. Lense,Miriam D. Lense,Reyna L. Gordon,Reyna L. Gordon,Lea K. Davis +7 more
TL;DR: Although being a musician was related to a large number of occupational health problems, protective effects of musicianship were identified in which certain diagnoses were less common in musicians than in non-musicians, indicating that active musical engagement could have similar health benefits to athletic engagement.