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Martien J H Kas
Researcher at University of Groningen
Publications - 220
Citations - 8665
Martien J H Kas is an academic researcher from University of Groningen. The author has contributed to research in topics: Anorexia nervosa (differential diagnoses) & Anorexia. The author has an hindex of 44, co-authored 206 publications receiving 6658 citations. Previous affiliations of Martien J H Kas include University Medical Center Utrecht & Utrecht University.
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Journal ArticleDOI
Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders
Phil Lee,Verneri Anttila,Hyejung Won,Yen-Chen Anne Feng,Jacob Rosenthal,Zhaozhong Zhu,Elliot M. Tucker-Drob,Michel G. Nivard,Andrew D. Grotzinger,Danielle Posthuma,Meg M.-J. Wang,Dongmei Yu,Eli A. Stahl,Raymond K. Walters,Richard Anney,Laramie E. Duncan,Tian Ge,Rolf Adolfsson,Tobias Banaschewski,Sintia Iole Belangero,Edwin H. Cook,Giovanni Coppola,Eske M. Derks,Pieter J. Hoekstra,Jaakko Kaprio,Anna Keski-Rahkonen,George Kirov,George Kirov,Henry R. Kranzler,Jurjen J. Luykx,Luis Augusto Rohde,Clement C. Zai,Esben Agerbo,Maria Arranz,Philip Asherson,Marie Bækvad-Hansen,Gisli Baldursson,Mark A. Bellgrove,Richard A. Belliveau,Jan K. Buitelaar,Christie L. Burton,Jonas Bybjerg-Grauholm,Miquel Casas,Felecia Cerrato,Kimberly Chambert,Claire Churchhouse,Bru Cormand,Jennifer Crosbie,Søren Dalsgaard,Ditte Demontis,Alysa E. Doyle,Ashley Dumont,Josephine Elia,Jakob Grove,Olafur O Gudmundsson,Jan Haavik,Hakon Hakonarson,Christine Søholm Hansen,Catharina A. Hartman,Ziarih Hawi,Amaia Hervás,David M. Hougaard,Daniel P. Howrigan,Hailiang Huang,Jonna Kuntsi,Kate Langley,Klaus-Peter Lesch,Patrick W. L. Leung,Sandra K. Loo,Joanna Martin,Alicia R. Martin,James J. McGough,Sarah E. Medland,Jennifer L. Moran,Ole Mors,Preben Bo Mortensen,Robert D. Oades,Duncan S. Palmer,Carsten Bøcker Pedersen,Marianne Giørtz Pedersen,Triinu Peters,Timothy Poterba,Jesper Buchhave Poulsen,Josep Antoni Ramos-Quiroga,Andreas Reif,Marta Ribasés,Aribert Rothenberger,Paula Rovira,Cristina Sánchez-Mora,F. Kyle Satterstrom,Russell Schachar,María Soler Artigas,Stacy Steinberg,Hreinn Stefansson,Patrick Turley,G. Bragi Walters,Thomas Werge,Tetyana Zayats,Dan E. Arking,Francesco Bettella,Joseph D. Buxbaum,Jane H. Christensen,Ryan L. Collins,Hilary Coon,Silvia De Rubeis,Richard Delorme,Dorothy E. Grice,Thomas Hansen,Peter Holmans,Sigrun Hope,Christina M. Hultman,Lambertus Klei,Christine Ladd-Acosta,Páll Magnússon,Terje Nærland,Mette Nyegaard,Dalila Pinto,Per Qvist,Karola Rehnström,Abraham Reichenberg,Jennifer Reichert,Kathryn Roeder,Guy A. Rouleau,Evald Saemundsen,Stephen Sanders,Sven Sandin,Beate St Pourcain,Kari Stefansson,James S. Sutcliffe,Michael E. Talkowski,Lauren A. Weiss,A. Jeremy Willsey,Ingrid Agartz,Huda Akil,Diego Albani,Martin Alda,Thomas Damm Als,Adebayo Anjorin,Lena Backlund,Nicholas Bass,Michael Bauer,Bernhard T. Baune,Frank Bellivier,Sarah E. Bergen,Wade H. Berrettini,Joanna M. Biernacka,Douglas Blackwood,Erlend Bøen,Monika Budde,William E. Bunney,Margit Burmeister,William Byerley,Enda M. Byrne,Sven Cichon,Toni-Kim Clarke,Jonathan R. I. Coleman,Nicholas John Craddock,David Curtis,Piotr M. Czerski,Anders M. Dale,Nina Dalkner,Udo Dannlowski,Franziska Degenhardt,Arianna Di Florio,Torbjørn Elvsåshagen,Bruno Etain,Sascha B. Fischer,Andreas J. Forstner,Liz Forty,Josef Frank,Mark A. Frye,Janice M. Fullerton,Katrin Gade,Helena Gaspar,Elliot S. Gershon,Michael Gill,Fernando S. Goes,Scott D. Gordon,Katherine Gordon-Smith,Melissa J. Green,Tiffany A. Greenwood,Maria Grigoroiu-Serbanescu,Jose Guzman-Parra,Joanna Hauser,Martin Hautzinger,Urs Heilbronner,Stefan Herms,Per Hoffmann,Dominic Holland,Stéphane Jamain,Ian Jones,Lisa Jones,Radhika Kandaswamy,John R. Kelsoe,James L. Kennedy,Oedegaard Ketil Joachim,Sarah Kittel-Schneider,Manolis Kogevinas,Anna C. Koller,Catharina Lavebratt,Cathryn M. Lewis,Qingqin S. Li,Jolanta Lissowska,Loes M. Olde Loohuis,Susanne Lucae,Anna Maaser,Ulrik Fredrik Malt,Nicholas G. Martin,Lina Martinsson,Susan L. McElroy,Francis J. McMahon,Andrew McQuillin,Ingrid Melle,Andres Metspalu,Vincent Millischer,Philip B. Mitchell,Grant W. Montgomery,Gunnar Morken,Derek W. Morris,Bertram Müller-Myhsok,Niamh Mullins,Richard M. Myers,Caroline M. Nievergelt,Merete Nordentoft,Annelie Nordin Adolfsson,Markus M. Nöthen,Roel A. Ophoff,Michael John Owen,Sara A. Paciga,Carlos N. Pato,Michele T. Pato,Roy H. Perlis,Amy Perry,James B. Potash,Céline S. Reinbold,Marcella Rietschel,Margarita Rivera,Mary Roberson,Martin Schalling,Peter R. Schofield,Thomas G. Schulze,Laura J. Scott,Alessandro Serretti,Engilbert Sigurdsson,Olav B. Smeland,Eystein Stordal,Fabian Streit,Jana Strohmaier,Thorgeir E. Thorgeirsson,Jens Treutlein,Gustavo Turecki,Arne E. Vaaler,Eduard Vieta,John B. Vincent,Yunpeng Wang,Stephanie H. Witt,Peter P. Zandi,Roger A.H. Adan,Lars Alfredsson,Tetsuya Ando,Harald N. Aschauer,Jessica H. Baker,Vladimir Bencko,Andrew W. Bergen,Andreas Birgegård,Vesna Boraska Perica,Harry Brandt,Roland Burghardt,Laura Carlberg,Matteo Cassina,Maurizio Clementi,Philippe Courtet,Steven Crawford,Scott J. Crow,James J. Crowley,Unna N. Danner,Oliver S. P. Davis,Daniela Degortes,Janiece E. DeSocio,Danielle M. Dick,Christian Dina,Elisa Docampo,Karin Egberts,Stefan Ehrlich,Thomas Espeseth,Fernando Fernández-Aranda,Manfred M. Fichter,Lenka Foretova,Monica Forzan,Giovanni Gambaro,Ina Giegling,Fragiskos Gonidakis,Philip Gorwood,Monica Gratacos Mayora,Yiran Guo,Katherine A. Halmi,Konstantinos Hatzikotoulas,Johannes Hebebrand,Sietske G. Helder,Beate Herpertz-Dahlmann,Wolfgang Herzog,Anke Hinney,Hartmut Imgart,Susana Jiménez-Murcia,Craig Johnson,Jennifer Jordan,Antonio Julià,Deborah Kaminská,Leila Karhunen,Andreas Karwautz,Martien J H Kas,Walter H. Kaye,Martin A. Kennedy,Youl-Ri Kim,Lars Klareskog,Kelly L. Klump,Gun Peggy Knudsen,Mikael Landén,Stephanie Le Hellard,Robert D. Levitan,Dong Li,Paul Lichtenstein,Mario Maj,Sara Marsal,Sara McDevitt,James R. Mitchell,Palmiero Monteleone,Alessio Maria Monteleone,Melissa A. Munn-Chernoff,Benedetta Nacmias,Marie Navratilova,Julie K. O'Toole,Leonid Padyukov,Jacques Pantel,Hana Papezova,Raquel Rabionet,Anu Raevuori,Nicolas Ramoz,Ted Reichborn-Kjennerud,Valdo Ricca,Marion Roberts,Dan Rujescu,Filip Rybakowski,André Scherag,Ulrike Schmidt,Jochen Seitz,Lenka Slachtova,Margarita C T Slof-Op 't Landt,Agnieszka Słopień,Sandro Sorbi,Lorraine Southam,Michael Strober,Alfonso Tortorella,Federica Tozzi,Janet Treasure,Konstantinos Tziouvas,Annemarie A. van Elburg,Tracey D. Wade,Gudrun Wagner,Esther Walton,Hunna J. Watson,H-Erich Wichmann,D. Blake Woodside,Eleftheria Zeggini,Stephanie Zerwas,Stephan Zipfel,Mark Adams,Till F. M. Andlauer,Klaus Berger,Elisabeth B. Binder,Dorret I. Boomsma,Enrique Castelao,Lucía Colodro-Conde,Nese Direk,Anna R. Docherty,Enrico Domenici,Katharina Domschke,Erin C. Dunn,Jerome C. Foo,E.J.C. de Geus,Hans J. Grabe,Steven P. Hamilton,Carsten Horn,Jouke-Jan Hottenga,David M. Howard,Marcus Ising,Stefan Kloiber,Douglas F. Levinson,Glyn Lewis,Patrik K. E. Magnusson,Hamdi Mbarek,Christel M. Middeldorp,Sara Mostafavi,Dale R. Nyholt,Brenda W.J.H. Penninx,Roseann E. Peterson,Giorgio Pistis,David J. Porteous,Martin Preisig,Jorge A. Quiroz,Catherine Schaefer,Eva C. Schulte,Jianxin Shi,Daniel J. Smith,Pippa A. Thomson,Henning Tiemeier,Rudolf Uher,Sandra Van der Auwera,Myrna M. Weissman,Madeline Alexander,Martin Begemann,Elvira Bramon,Nancy G. Buccola,Murray J. Cairns,Dominique Campion,Vaughan J. Carr,C. Robert Cloninger,David Cohen,David A. Collier,Aiden Corvin,Lynn E. DeLisi,Gary Donohoe,Frank Dudbridge,Jubao Duan,Robert B. Freedman,Pablo V. Gejman,Vera Golimbet,Stephanie Godard,Hannelore Ehrenreich,Annette M. Hartmann,Frans Henskens,Masashi Ikeda,Nakao Iwata,Assen Jablensky,Inge Joa,Erik G. Jönsson,Brian Kelly,Jo Knight,Bettina Konte,Claudine Laurent-Levinson,James Lee,Todd Lencz,Bernard Lerer,Carmel M. Loughland,Anil K. Malhotra,Jacques Mallet,Colm McDonald,Marina Mitjans,Bryan J. Mowry,Kieran C. Murphy,Robin M. Murray,F. Anthony O'Neill,Sang-Yun Oh,Aarno Palotie,Christos Pantelis,Ann E. Pulver,Tracey L. Petryshen,Digby Quested,Brien P. Riley,Alan R. Sanders,Ulrich Schall,Sibylle G. Schwab,Rodney J. Scott,Pak C. Sham,Jeremy M. Silverman,Kang Sim,Agnes A. Steixner,Paul A. Tooney,Jim van Os,Marquis P. Vawter,Dermot Walsh,Mark Weiser,Dieter B. Wildenauer,Nigel Williams,Brandon Wormley,Fuquan Zhang,Christos Androutsos,Paul D. Arnold,Cathy L. Barr,Csaba Barta,Katharina Bey,O. Joseph Bienvenu,Donald W. Black,Lawrence W. Brown,Cathy L. Budman,Danielle C. Cath,Keun-Ah Cheon,Valentina Ciullo,Barbara J. Coffey,Daniele Cusi,Lea K. Davis,Damiaan Denys,Christel Depienne,Andrea Dietrich,Valsamma Eapen,Peter Falkai,Thomas V. Fernandez,Blanca Garcia-Delgar,Daniel A. Geller,Donald L. Gilbert,Marco A. Grados,Erica Greenberg,Edna Grünblatt,Julie Hagstrøm,Gregory L. Hanna,Andreas Hartmann,Tammy Hedderly,Gary A. Heiman,Isobel Heyman,Hyun Ju Hong,Alden Y. Huang,Chaim Huyser,Laura Ibanez-Gomez,Ekaterina A. Khramtsova,Young Key Kim,Young Shin Kim,Robert A. King,Yun-Joo Koh,Anastasios Konstantinidis,Sodahm Kook,Samuel Kuperman,Bennett L. Leventhal,Christine Lochner,Andrea G. Ludolph,Marcos Madruga-Garrido,Irene A. Malaty,Athanasios Maras,James T. McCracken,Inge A. Meijer,Pablo Mir,Astrid Morer,Kirsten R. Müller-Vahl,Alexander Münchau,Tara Murphy,Allan L. Naarden,Peter Nagy,Gerald Nestadt,Paul S. Nestadt,Humberto Nicolini,Erika L. Nurmi,Michael S. Okun,Peristera Paschou,Fabrizio Piras,Federica Piras,Christopher Pittenger,Kerstin J. Plessen,Margaret A. Richter,Renata Rizzo,Mary M. Robertson,Veit Roessner,Stephan Ruhrmann,Jack Samuels,Paul Sandor,Monika Schlögelhofer,Eun-Young Shin,Harvey S. Singer,Dong-Ho Song,Jungeun Song,Gianfranco Spalletta,Dan J. Stein,S. Evelyn Stewart,Eric A. Storch,Barbara E. Stranger,Manfred Stuhrmann,Zsanett Tarnok,Jay A. Tischfield,Jennifer Tübing,Frank Visscher,Nienke Vulink,Michael Wagner,Susanne Walitza,Sina Wanderer,Martin Woods,Yulia Worbe,Gwyneth Zai,Samuel H. Zinner,Patrick F. Sullivan,Barbara Franke,Mark J. Daly,Cynthia M. Bulik,Andrew M. McIntosh,Michael Conlon O'Donovan,Amanda B Zheutlin,Ole A. Andreassen,Anders D. Børglum,Gerome Breen,Howard J. Edenberg,Ayman H. Fanous,Stephen V. Faraone,Joel Gelernter,Carol A. Mathews,Manuel Mattheisen,Karen S. Mitchell,Michael C. Neale,John I. Nurnberger,Stephan Ripke,Susan L. Santangelo,Jeremiah M. Scharf,Murray B. Stein,Laura M. Thornton,James T.R. Walters,Naomi R. Wray,Naomi R. Wray,Daniel H. Geschwind,Benjamin M. Neale,Kenneth S. Kendler,Jordan W. Smoller +606 more
TL;DR: Genetic influences on psychiatric disorders transcend diagnostic boundaries, suggesting substantial pleiotropy of contributing loci within genes that show heightened expression in the brain throughout the lifespan, beginning prenatally in the second trimester, and play prominent roles in neurodevelopmental processes.
Journal ArticleDOI
Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa
Hunna J. Watson,Hunna J. Watson,Hunna J. Watson,Zeynep Yilmaz,Laura M. Thornton,Christopher Hübel,Christopher Hübel,Jonathan R. I. Coleman,Jonathan R. I. Coleman,Helena Gaspar,Helena Gaspar,Julien Bryois,Anke Hinney,Virpi M. Leppä,Manuel Mattheisen,Sarah E. Medland,Stephan Ripke,Stephan Ripke,Stephan Ripke,Shuyang Yao,Paola Giusti-Rodríguez,Ken B. Hanscombe,Kirstin L. Purves,Roger A.H. Adan,Roger A.H. Adan,Lars Alfredsson,Tetsuya Ando,Ole A. Andreassen,Jessica H. Baker,Wade H. Berrettini,Ilka Boehm,Claudette Boni,Vesna Boraska Perica,Vesna Boraska Perica,Katharina Buehren,Roland Burghardt,Matteo Cassina,Sven Cichon,Maurizio Clementi,Roger D. Cone,Philippe Courtet,Scott J. Crow,James J. Crowley,James J. Crowley,Unna N. Danner,Oliver S. P. Davis,Martina de Zwaan,George Dedoussis,Daniela Degortes,Janiece E. DeSocio,Danielle M. Dick,Dimitris Dikeos,Christian Dina,Monika Dmitrzak-Weglarz,Elisa Docampo,Laramie E. Duncan,Karin Egberts,Stefan Ehrlich,Geòrgia Escaramís,Tõnu Esko,Tõnu Esko,Xavier Estivill,Anne Farmer,Angela Favaro,Fernando Fernández-Aranda,Manfred M. Fichter,Krista Fischer,Manuel Föcker,Lenka Foretova,Andreas J. Forstner,Monica Forzan,Christopher S. Franklin,Steven Gallinger,Ina Giegling,Johanna Giuranna,Fragiskos Gonidakis,Philip Gorwood,Philip Gorwood,Monica Gratacos Mayora,Sébastien Guillaume,Yiran Guo,Hakon Hakonarson,Hakon Hakonarson,Konstantinos Hatzikotoulas,Joanna Hauser,Johannes Hebebrand,Sietske G. Helder,Stefan Herms,Stefan Herms,Stefan Herms,Beate Herpertz-Dahlmann,Wolfgang Herzog,Laura M. Huckins,Laura M. Huckins,James I. Hudson,Hartmut Imgart,Hidetoshi Inoko,Vladimir Janout,Susana Jiménez-Murcia,Antonio Julià,Gursharan Kalsi,Deborah Kaminská,Jaakko Kaprio,Leila Karhunen,Andreas Karwautz,Martien J H Kas,Martien J H Kas,James L. Kennedy,James L. Kennedy,Anna Keski-Rahkonen,Kirsty Kiezebrink,Youl-Ri Kim,Lars Klareskog,Kelly L. Klump,Gun Peggy Knudsen,Maria La Via,Stephanie Le Hellard,Stephanie Le Hellard,Robert D. Levitan,Robert D. Levitan,Dong Li,Lisa R. Lilenfeld,Bochao Danae Lin,Jolanta Lissowska,Jurjen J. Luykx,Pierre J. Magistretti,Pierre J. Magistretti,Mario Maj,Katrin Männik,Katrin Männik,Sara Marsal,Christian R. Marshall,Morten Mattingsdal,Sara McDevitt,Peter McGuffin,Andres Metspalu,Ingrid Meulenbelt,Nadia Micali,Nadia Micali,Nadia Micali,Karen S. Mitchell,Alessio Maria Monteleone,Palmiero Monteleone,Melissa A. Munn-Chernoff,Benedetta Nacmias,Marie Navratilova,Ioanna Ntalla,Julie K. O'Toole,Roel A. Ophoff,Roel A. Ophoff,Leonid Padyukov,Aarno Palotie,Aarno Palotie,Aarno Palotie,Jacques Pantel,Hana Papezova,Dalila Pinto,Raquel Rabionet,Raquel Rabionet,Anu Raevuori,Nicolas Ramoz,Ted Reichborn-Kjennerud,Ted Reichborn-Kjennerud,Valdo Ricca,Valdo Ricca,Samuli Ripatti,Samuli Ripatti,Franziska Ritschel,Marion Roberts,Marion Roberts,Marion Roberts,Alessandro Rotondo,Dan Rujescu,Dan Rujescu,Filip Rybakowski,Paolo Santonastaso,André Scherag,Stephen W. Scherer,Ulrike Schmidt,Ulrike Schmidt,Nicholas J. Schork,Alexandra Schosser,Jochen Seitz,Lenka Slachtova,P. Eline Slagboom,Margarita C T Slof-Op 't Landt,Agnieszka Słopień,Sandro Sorbi,Beata Świątkowska,Jin P. Szatkiewicz,Ioanna Tachmazidou,Elena Tenconi,Alfonso Tortorella,Alfonso Tortorella,Federica Tozzi,Janet Treasure,Janet Treasure,Artemis Tsitsika,Marta Tyszkiewicz-Nwafor,Konstantinos Tziouvas,Annemarie A. van Elburg,Eric F. van Furth,Gudrun Wagner,Esther Walton,Elisabeth Widen,Eleftheria Zeggini,Stephanie Zerwas,Stephan Zipfel,Andrew W. Bergen,Joseph M. Boden,Harry Brandt,Steven Crawford,Katherine A. Halmi,L. John Horwood,Craig Johnson,Allan S. Kaplan,Allan S. Kaplan,Walter H. Kaye,James E. Mitchell,Catherine M. Olsen,John F. Pearson,Nancy L. Pedersen,Michael Strober,Michael Strober,Thomas Werge,David C. Whiteman,D. Blake Woodside,Garret D. Stuber,Scott D. Gordon,Jakob Grove,Anjali K. Henders,Anders Juréus,Katherine M. Kirk,Janne Tidselbak Larsen,Janne Tidselbak Larsen,Richard Parker,Liselotte Petersen,Liselotte Petersen,Jennifer Jordan,Martin A. Kennedy,Grant W. Montgomery,Grant W. Montgomery,Tracey D. Wade,Andreas Birgegård,Andreas Birgegård,Paul Lichtenstein,Claes Norring,Claes Norring,Mikael Landén,Mikael Landén,Nicholas G. Martin,Preben Bo Mortensen,Preben Bo Mortensen,Patrick F. Sullivan,Patrick F. Sullivan,Gerome Breen,Gerome Breen,Cynthia M. Bulik,Cynthia M. Bulik +258 more
TL;DR: The genetic architecture of anorexia nervosa mirrors its clinical presentation, showing significant genetic correlations with psychiatric disorders, physical activity, and metabolic (including glycemic), lipid and anthropometric traits, independent of the effects of common variants associated with body-mass index.
A genome-wide association study of anorexia nervosa
Vesna Boraska,Christopher S. Franklin,James A B Floyd,Laura M. Thornton,Laura M. Huckins,L. Southam,Nigel W. Rayner,Ioanna Tachmazidou,Kelly L. Klump,Janet Treasure,Cathryn M. Lewis,Ulrike Schmidt,Federica Tozzi,Kirsty Kiezebrink,Johannes Hebebrand,Philip Gorwood,Roger A.H. Adan,Martien J H Kas,Angela Favaro,Paolo Santonastaso,Fernando Fernández-Aranda,Mònica Gratacòs,Filip Rybakowski,Monika Dmitrzak-Weglarz,Jaakko Kaprio,Anna Keski-Rahkonen,Anu Raevuori,E. F. van Furth,M. C. T. Slof-Op 't Landt,James I. Hudson,Ted Reichborn-Kjennerud,Gun Peggy Knudsen,Palmiero Monteleone,Allan S. Kaplan,Andreas Karwautz,Hakon Hakonarson,Wade H. Berrettini,Yiran Guo,Dong Li,Nicholas J. Schork,Gen Komaki,Tetsuya Ando,Hidetoshi Inoko,Tõnu Esko,K. Fischer,K. Maennik,Andres Metspalu,Jessica H. Baker,Roger D. Cone,Jennifer Dackor,Janiece E. DeSocio,Chris Hilliard,Julie K. O'Toole,Johannes Pantel,Jin P. Szatkiewicz,C. Taico,Stephanie Zerwas,Sara E. Trace,Oliver S. P. Davis,Sietske G. Helder,Katharina Buehren,Roland Burghardt,M. de Zwaan,Karin Egberts,Stefan Ehrlich,Beate Herpertz-Dahlmann,Wolfgang Herzog,Hartmut Imgart,André Scherag,S. Scherag,Stephan Zipfel,Claudette Boni,Nicolas Ramoz,Audrey Versini,Marek K. Brandys,Unna N. Danner,C. G. F. de Kovel,Judith Hendriks,B. P. C. Koeleman,Roel A. Ophoff,Eric Strengman,A. A. van Elburg,Alice Bruson,Maurizio Clementi,Daniela Degortes,Monica Forzan,Elena Tenconi,Elisa Docampo,Geòrgia Escaramís,Susana Jiménez-Murcia,Jolanta Lissowska,Andrzej Rajewski,Neonilia Szeszenia-Dabrowska,Agnieszka Słopień,Joanna Hauser,Leila Karhunen,Ingrid Meulenbelt,P.E. Slagboom,Alfonso Tortorella,Mario Maj,George Dedoussis,Dimitris Dikeos,Fragiskos Gonidakis,Konstantinos Tziouvas,Artemis Tsitsika,Hana Papezova,L. Slachtova,D. Martaskova,James L. Kennedy,Robert D. Levitan,Zeynep Yilmaz,Julia Huemer,Doris Koubek,Elisabeth Merl,Günter P. Wagner,Paul Lichtenstein,Gerome Breen,Sarah Cohen-Woods,Anne Farmer,Peter McGuffin,Sven Cichon,Ina Giegling,Stefan Herms,Dan Rujescu,Stefan Schreiber,H-E Wichmann,Christian Dina,Robert Sladek,Giovanni Gambaro,Nicole Soranzo,Antonio Julià,Sara Marsal,Raquel Rabionet,Valerie Gaborieau,Danielle M. Dick,Aarno Palotie,Samuli Ripatti,Elisabeth Widen,Ole A. Andreassen,Thomas Espeseth,Astri J. Lundervold,Ivar Reinvang,Vidar M. Steen,S. Le Hellard,Morten Mattingsdal,Ioanna Ntalla,Vladimir Bencko,Lenka Foretová,Vladimir Janout,Marie Navratilova,S. Gallinger,Dalila Pinto,Stephen W. Scherer,Harald N. Aschauer,Laura Carlberg,Alexandra Schosser,Lars Alfredsson,Bo Ding,Lars Klareskog,Leonid Padyukov,Philippe Courtet,Sébastien Guillaume,Isabelle Jaussent,Chris Finan,Gursharan Kalsi,Marion Roberts,Darren W. Logan,Leena Peltonen,Graham R S Ritchie,Jeffrey C. Barrett,Xavier Estivill,Anke Hinney,Patrick F. Sullivan,David A. Collier,Eleftheria Zeggini,Cynthia M. Bulik +175 more
TL;DR: The accrual of large genotyped AN case-control samples should be an immediate priority for the field, suggesting that true findings exist but the sample, the largest yet reported, was underpowered for their detection.
Journal ArticleDOI
A genome-wide association study of anorexia nervosa
Ted Reichborn-Kjennerud,Gun Peggy Knudsen,Ole A. Andreassen,Thomas Espeseth,Astri J. Lundervold,Ivar Reinvang,Vidar M. Steen,Stephanie Le Hellard,Morten Mattingsdal,Boraske,Christopher S. Franklin,James A B Floyd,Laura M. Thornton,Laura M. Huckins,L. Southam,Nigel W. Rayner,Ioanna Tachmazidou,Kelly L. Klump,Jim Treasure,Cathryn M. Lewis,Ulrike Schmidt,Federica Tozzi,Kirsty Kiezebrink,Johannes Hebebrand,Philip Gorwood,Roger A.H. Adan,Martien J H Kas,Angela Favaro,Paolo Santonastaso,Fernando Fernández-Aranda,Mònica Gratacòs,Finn Rybakowski,Monika Dmitrzak-Weglarz,Jaakko Kaprio,Anna Keski-Rahkonen,Anu Raevuori,E. F. van Furth,M. C. T. Slof-Op 't Landt,James I. Hudson,Palmiero Monteleone,Palmiero Monteleone,Allan S. Kaplan,Andreas Karwautz,Hakon Hakonarson,Wade H. Berrettini,Yiran Guo,Dong Li,Nicholas J. Schork,Gen Komaki,Tetsuya Ando,Hidetoshi Inoko +50 more
TL;DR: This article performed a GWAS in 2907 cases with AN from 14 countries (15 sites) and 14 860 ancestrally matched controls as part of the Genetic Consortium for AN (GCAN) and the Wellcome Trust Case Control Consortium 3 (WTCCC3).
Journal ArticleDOI
The MC4 receptor and control of appetite
TL;DR: This review addresses the role of the MC system in different aspects of feeding behaviour and application of MCR agonists in humans has already revealed side effects, such as penile erections, which may complicate introduction of these drugs in the treatment of obesity.