L
Ludhmila Abrahão Hajjar
Researcher at University of São Paulo
Publications - 242
Citations - 8857
Ludhmila Abrahão Hajjar is an academic researcher from University of São Paulo. The author has contributed to research in topics: Medicine & Randomized controlled trial. The author has an hindex of 39, co-authored 214 publications receiving 6499 citations. Previous affiliations of Ludhmila Abrahão Hajjar include Sapienza University of Rome & Università Campus Bio-Medico.
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Journal ArticleDOI
Transfusion Requirements After Cardiac Surgery: the TRACS Randomized Controlled Trial
Ludhmila Abrahão Hajjar,Jean Louis Vincent,Filomena Regina Barbosa Gomes Galas,R Nakamura,Carolina Maria Pinto Domingues Carvalho Silva,Marilia H. Santos,Julia Tizue Fukushima,Roberto Kalil Filho,Denise B. Sierra,Neuza Lopes,Thais Mauad,Aretusa C. Roquim,M Sundin,Wanderson C Leão,José Paulo Almeida,Pablo Maria Alberto Pomerantzeff,Luís Alberto Oliveira Dallan,Fábio Biscegli Jatene,Noedir Antônio Groppo Stolf,José Otávio Costa Auler +19 more
TL;DR: Among patients undergoing cardiac surgery, the use of a restrictive perioperative transfusion strategy compared with a more liberal strategy resulted in noninferior rates of the combined outcome of 30-day all-cause mortality and severe morbidity.
Journal ArticleDOI
Effect of High vs Low Doses of Chloroquine Diphosphate as Adjunctive Therapy for Patients Hospitalized With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection: A Randomized Clinical Trial.
Mayla Gabriela Silva Borba,Fernando Fonseca Almeida Val,Vanderson de Souza Sampaio,Márcia A. A. Alexandre,Gisely Cardoso de Melo,Marcelo A M Brito,Maria Paula Gomes Mourão,Jose Diego Brito-Sousa,Djane Clarys Baia-da-Silva,Marcus Vinitius de Farias Guerra,Ludhmila Abrahão Hajjar,R. Pinto,Antônio Alcirley da Silva Balieiro,Antonio G. Pacheco,James D. Santos,Felipe Gomes Naveca,Mariana Simão Xavier,André M. Siqueira,Alexandre Vargas Schwarzbold,Julio Croda,Julio Croda,Maurício Lacerda Nogueira,Gustavo Adolfo Sierra Romero,Quique Bassat,Cor Jesus Fernandes Fontes,Bernardino Cláudio de Albuquerque,Cláudio Tadeu Daniel-Ribeiro,Wuelton Marcelo Monteiro,Marcus Lacerda +28 more
TL;DR: The preliminary findings of this study suggest that the higher CQ dosage should not be recommended for critically ill patients with COVID-19 because of its potential safety hazards, especially when taken concurrently with azithromycin and oseltamivir.
Journal ArticleDOI
Lung Pathology in Fatal Novel Human Influenza A (H1N1) Infection
Thais Mauad,Ludhmila Abrahão Hajjar,Giovanna D. Callegari,Luiz Fernando Ferraz da Silva,Denise Schout,Filomena Regina Barbosa Gomes Galas,Venancio Avancini Ferreira Alves,Denise Maria Avancini Costa Malheiros,José Otávio Costa Auler,Aurea F. Ferreira,Marcela R. L. Borsato,Stephania M. Bezerra,Paulo Sampaio Gutierrez,Elia Garcia Caldini,Carlos Augusto Pasqualucci,Marisa Dolhnikoff,Paulo Hilário Nascimento Saldiva +16 more
TL;DR: Autopsies have shown that the main pathological changes associated with S-OIV infection are localized to the lungs, where three distinct histological patterns can be identified.
Journal ArticleDOI
Carvedilol for Prevention of Chemotherapy-Related Cardiotoxicity: The CECCY Trial.
Mônica Samuel Avila,Silvia Moreira Ayub-Ferreira,Mauro Rogerio de Barros Wanderley Jr.,Fátima das Dores Cruz,Sara Michelly Gonçalves Brandão,Vagner Oliveira Carvalho Rigaud,Marilia Harumi Higuchi-dos-Santos,Ludhmila Abrahão Hajjar,Roberto Kalil Filho,Paulo M. Hoff,Marina Sahade,Marcela S. M. Ferrari,Romulo Leopoldo de Paula Costa,Max S. Mano,Cecilia Cruz,Maria Cristina Donadio Abduch,Marco Stephan Lofrano Alves,Guilherme Veiga Guimarães,Victor Sarli Issa,Márcio Sommer Bittencourt,Edimar Alcides Bocchi +20 more
TL;DR: In this largest clinical trial of β-blockers for prevention of cardiotoxicity under contemporary ANT dosage, the use of carvedilol resulted in a significant reduction in troponin levels and diastolic dysfunction.
Journal ArticleDOI
Effect of Vitamin C, Hydrocortisone, and Thiamine vs Hydrocortisone Alone on Time Alive and Free of Vasopressor Support Among Patients With Septic Shock: The VITAMINS Randomized Clinical Trial
Tomoko Fujii,Tomoko Fujii,Nora Luethi,Nora Luethi,Paul J Young,Paul J Young,Daniel Frei,Glenn M Eastwood,Glenn M Eastwood,Craig French,Craig French,Adam M. Deane,Yahya Shehabi,Yahya Shehabi,Ludhmila Abrahão Hajjar,Gisele Augusto Rodrigues de Oliveira,Andrew A. Udy,Andrew A. Udy,Neil Orford,Neil Orford,Neil Orford,Samantha J Edney,Anna Hunt,Harriet L Judd,Laurent Bitker,Luca Cioccari,Luca Cioccari,Luca Cioccari,Thummaporn Naorungroj,Thummaporn Naorungroj,Fumitaka Yanase,Fumitaka Yanase,Samantha Bates,Forbes McGain,Elizabeth P Hudson,Wisam Al-Bassam,Dhiraj Bhatia Dwivedi,Chloe Peppin,Phoebe McCracken,Judit Orosz,Michael Bailey,Michael Bailey,Rinaldo Bellomo,Rinaldo Bellomo,Rinaldo Bellomo +44 more
TL;DR: Treatment with intravenous vitamin C, hydrocortisone, and thiamine did not significantly improve the duration of time alive and free of vasopressor administration in patients with septic shock, suggesting that treatment with the combination does not lead to a more rapid resolution of septicshock.