M
Mafalda Antunes-Ferreira
Researcher at VU University Medical Center
Publications - 4
Citations - 52
Mafalda Antunes-Ferreira is an academic researcher from VU University Medical Center. The author has contributed to research in topics: Cancer & Internal medicine. The author has an hindex of 1, co-authored 1 publications receiving 4 citations.
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Journal ArticleDOI
Circulating platelets as liquid biopsy sources for cancer detection.
TL;DR: The usability of platelets as a liquid biopsy for the detection of cancer is addressed, describing several studies that support the use of platelet biomarkers in cancer diagnostics and discussing what is still lacking for their implementation into the clinic.
Journal ArticleDOI
Detection and localization of early- and late-stage cancers using platelet RNA.
Sjors G J G In 't Veld,Mohammad Arkani,Edward Post,Mafalda Antunes-Ferreira,Silvia D’Ambrosi,Daan C L Vessies,Lisa Vermunt,Adrienne Vancura,Mirte Muller,Anna-Larissa N. Niemeijer,Jihane Tannous,Laura L. Meijer,Tessa Y S Le Large,Giulia Mantini,Niels Wondergem,K.M. Heinhuis,Sandra van Wilpe,A.J. Smits,Esther E.E. Drees,Eva Roos,Cyra E. Leurs,Lee Ann Tjon Kon Fat,Ewoud J. van der Lelij,Govert Dwarshuis,Maarten J. Kamphuis,Lisanne E Visser,Romée Harting,Annemijn Gregory,Markus Schweiger,Laurine E. Wedekind,J. Ramaker,Kenn Zwaan,Heleen Verschueren,Idris Bahce,Adrianus J. de Langen,Egbert F. Smit,Michel M. van den Heuvel,Koen J. Hartemink,Marijke J.E. Kuijpers,Mirjam G.A. oude Egbrink,Arjan W. Griffioen,R.L. Rossel,T. Jeroen N. Hiltermann,Elizabeth Lee-Lewandrowski,Kent B. Lewandrowski,Philip C. De Witt Hamer,Mathilde C.M. Kouwenhoven,Jaap C. Reijneveld,William P.J. Leenders,Ann Hoeben,Irma M. Verdonck-de Leeuw,C. René Leemans,Robert J. Baatenburg de Jong,Chris H.J. Terhaard,Robert P. Takes,Johannes A. Langendijk,Saskia C.A. de Jager,Adriaan O. Kraaijeveld,Gerard Pasterkamp,Minke Smits,Jack A. Schalken,Sylwia Łapińska-Szumczyk,Anna Łojkowska,Anna J. Zaczek,Henk M. Lokhorst,N. W. C. J. van de Donk,Inger S. Nijhof,Henk-Jan Prins,Josée M. Zijlstra,Sander Idema,Johannes C. Baayen,Charlotte E. Teunissen,Joep Killestein,Marc G. Besselink,Lindsay Brammen,Thomas Bachleitner-Hofmann,Farrah J. Mateen,John T. M. Plukker,Michal Heger,Quirijn de Mast,Ton Lisman,D. Michiel Pegtel,Harm Jan Bogaard,Jacek Jassem,Anna Supernat,Niven Mehra,Winald R. Gerritsen,Cornelis D. de Kroon,Christianne A. R. Lok,Jürgen Piek,Neeltje Steeghs,Winan J. van Houdt,Ruud H. Brakenhoff,Gabe S. Sonke,Henk M.W. Verheul,Elisa Giovannetti,Geert Kazemier,Siamack Sabrkhany,Ed Schuuring,Erik A. Sistermans,Rob M. F. Wolthuis,Hanne Meijers-Heijboer,Josephine C. Dorsman,Cees B.M. Oudejans,Bauke Ylstra,Bart A. Westerman,D. Van Den Broek,Danijela Koppers-Lalic,Pieter Wesseling,R. Jonas A. Nilsson,W. Peter Vandertop,David P. Noske,Bakhos A. Tannous,Nik Sol,Myron G. Best,Thomas Wurdinger +115 more
TL;DR: In this article , a tumor-educated platelet (TEP) RNA-based blood tests enable the detection of 18 cancer types with 99% specificity in asymptomatic controls.
Journal ArticleDOI
Combinatorial Blood Platelets-Derived circRNA and mRNA Signature for Early-Stage Lung Cancer Detection
Silvia D’Ambrosi,Stavros Giannoukakos,Mafalda Antunes-Ferreira,Carlos Pedraz-Valdunciel,Jillian Wilhelmina Paulina Bracht,Nicolas Potie,Ana Giménez-Capitán,Michael Hackenberg,Alberto Fernandez Hilario,Miguel Angel Molina-Vila,Rafael Rosell,T Würdinger,Danijela Koppers-Lalic +12 more
TL;DR: In this paper , the authors investigated the synergistic contributions of circRNA and mRNA signatures derived from blood platelets as biomarkers for lung cancer detection and developed a comprehensive bioinformatics pipeline permitting an analysis of platelet-circRNA and RNA derived from non-cancer individuals and lung cancer patients.
Journal ArticleDOI
Tumor-educated platelet blood tests for Non-Small Cell Lung Cancer detection and management
Mafalda Antunes-Ferreira,Silvia D’Ambrosi,Mohammad Arkani,Edward Post,Sjors G J G In 't Veld,J. Ramaker,Kenn Zwaan,Laurine E. Wedekind,Arjan W. Griffioen,Mirjam G.A. oude Egbrink,Marijke J.E. Kuijpers,D. Van Den Broek,David P. Noske,Koen J. Hartemink,Siamack Sabrkhany,Idris Bahce,Nik Sol,Harm Jan Bogaard,Danijela Koppers-Lalic,Myron G. Best,Thomas Wurdinger +20 more
TL;DR: In this paper , a particle-swarm optimization machine learning algorithm was used for the selection of an 881 RNA biomarker panel (AUC 0.88) for lung cancer patients.