Maren Struve

TL;DR: The strategies the IMAGEN consortium used to meet the challenges posed by large-scale multicentre imaging–genomics investigations are described, including standardization of the clinical, psychometric and neuroimaging-acquisition protocols, development of a central database for efficient analyses of large multimodal data sets and new analytic approaches to large- scale genetic neuroim imaging analyses.

TL;DR: The results indicate that both neural endophenotypes and genetic variation give rise to the various manifestations of impulsive behavior.

TL;DR: There is widespread recognition that consistency between research centres in the ways that patients with tinnitus are assessed and outcomes following interventions are measured would facilitate more effective co-operation and more meaningful evaluations and comparisons of outcomes.

TL;DR: It is suggested that reduced striatal activation operates as a mechanism across the risk spectrum for depression and is a behavioral indicator of positive valence systems, consistent with predictions based on the Research Domain Criteria.

TL;DR: It is suggested that a lower response to reward anticipation in the ventral striatum may be a vulnerability factor for the development of early nicotine use.