Catherine Mallik

TL;DR: The strategies the IMAGEN consortium used to meet the challenges posed by large-scale multicentre imaging–genomics investigations are described, including standardization of the clinical, psychometric and neuroimaging-acquisition protocols, development of a central database for efficient analyses of large multimodal data sets and new analytic approaches to large- scale genetic neuroim imaging analyses.

TL;DR: The results indicate that adolescents display a sex-dependent lateralization of amygdala activation that is also present in basic processes of emotional perception, which suggests aSex-dependent development of human emotion processing and may further implicate possible etiological pathways for mental disorders most frequent in adolescent males.

TL;DR: High FA was detected in resilient adolescents in an anterior CC region projecting to frontal areas subserving cognitive resources, indicating resilience in adolescence may be related to white-matter microstructure.

TL;DR: Subth threshold depression in early adolescence might be associated with smaller gray and white matter volumes in regions of the frontal-striatal-limbic affective circuit, and the occurrence of depression in girls with subthreshold depression might be influenced by medial-prefrontal gray matter volume.

TL;DR: Cerebellar GM volumes in the right Lobule VI predict manual dexterity in healthy untrained humans when cerebellum-optimized VBM is employed, indicating that previous studies might have underestimated the importance of cerebellar in manual dexterity.