M
Martin Schaller
Researcher at University of Tübingen
Publications - 297
Citations - 14090
Martin Schaller is an academic researcher from University of Tübingen. The author has contributed to research in topics: Candida albicans & Rosacea. The author has an hindex of 59, co-authored 280 publications receiving 11850 citations.
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Journal ArticleDOI
T-helper-1-cell cytokines drive cancer into senescence
Heidi Braumüller,Thomas Wieder,Ellen Brenner,Sonja Aßmann,Matthias Hahn,Mohammed Alkhaled,Karin Schilbach,Frank Essmann,Manfred Kneilling,Christoph M. Griessinger,Felicia Ranta,Susanne Ullrich,Ralph Mocikat,Kilian Braungart,Tarun Mehra,Birgit Fehrenbacher,Julia Berdel,Heike Niessner,Friedegund Meier,Maries van den Broek,Hans-Ulrich Häring,Rupert Handgretinger,Leticia Quintanilla-Martinez,Falko Fend,Marina Pesic,Jürgen Bauer,Lars Zender,Martin Schaller,Klaus Schulze-Osthoff,Martin Röcken +29 more
TL;DR: The combined action of the T-helper-1-cell cytokines IFN-γ and tumour necrosis factor (TNF) directly induces permanent growth arrest in cancers, a general mechanism for arresting cancer progression.
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Radiation-induced epidermal growth factor receptor nuclear import is linked to activation of DNA-dependent protein kinase
Klaus Dittmann,Claus Mayer,Birgit Fehrenbacher,Martin Schaller,Uma Raju,Luka Milas,David J. Chen,Rainer Kehlbach,H. Peter Rodemann +8 more
TL;DR: The data implicate a novel function of the EGFR during DNA repair processes and radiation-induced activation of DNA-PK, inhibited DNA repair, and increased radiosensitivity of treated cells.
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Granulocytes govern the transcriptional response, morphology and proliferation of Candida albicans in human blood.
Chantal Fradin,Piet W. J. de Groot,Donna M. MacCallum,Martin Schaller,Frans M. Klis,Frank C. Odds,Bernhard Hube +6 more
TL;DR: In this paper, the influence of blood components on fungal growth, morphology and transcript profile during bloodstream infections was investigated, and it was found that neutrophils played a key role in stopping C. albicans growth, enhanced the fungal response to overcome nitrogen and carbohydrate starvation, and induced the expression of a large number of genes involved in the oxidative stress response.
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Reduction of disulphide bonds unmasks potent antimicrobial activity of human β-defensin 1
Bjoern O. Schroeder,Zhihong Wu,Sabine Nuding,Sabine Nuding,Sandra Groscurth,Moritz Marcinowski,Julia Beisner,Julia Beisner,Johannes Buchner,Martin Schaller,Eduard F. Stange,Jan Wehkamp,Jan Wehkamp,Jan Wehkamp +13 more
TL;DR: Reduced hBD-1 shields the healthy epithelium against colonisation by commensal bacteria and opportunistic fungi and against anaerobic, Gram-positive commensals of Bifidobacterium and Lactobacillus species.
Journal ArticleDOI
Transdifferentiation of Vascular Smooth Muscle Cells to Macrophage-Like Cells During Atherogenesis
Susanne Feil,Birgit Fehrenbacher,Robert Lukowski,Frank Essmann,Klaus Schulze-Osthoff,Martin Schaller,Robert Feil +6 more
TL;DR: It is found that medial SMCs can undergo clonal expansion and convert to macrophage-like cells that have lost classic SMC marker expression and make up a major component of advanced atherosclerotic lesions.