Matej Orešič

TL;DR: In this paper, the impact of maternal exposure to per-and polyfluoroalkyl substances (PFAS) on lipid composition of human breast milk was studied and the combined effect of maternal PFAS exposure and breast milk lipid composition on the growth of infants.

TL;DR: Treatment for patients with acute subdural haematoma with similar characteristics differed depending on the treating centre, because of variation in the preferred approach, and a treatment strategy preferring an aggressive approach of acute surgical evacuation over initial conservative treatment was not associated with better functional outcome.

TL;DR: The argument is made here that for adopting systems biology approaches to MetS an integrative framework is needed which glues the biological processes of MetS with specific physiological mechanisms and principles and that lipotoxicity is one such framework.

TL;DR: Transgenic overexpression of PPARγ in β-cells in diet-induced obesity negatively impacts whole-animal carbohydrate metabolism associated with altered islet lipid content, increased expression of β-oxidative genes, and reduced β-cell mass.

TL;DR: In this article, the role of cardiac glycosphingolipids in heart function was investigated using human myocardial biopsies, and it was shown that cardiac glucosylceramide was required to maintain β-adrenergic signalling and contractile capacity in cardiomyocytes and preserve normal heart function.