M
Matthew R. Garnett
Researcher at University of Cambridge
Publications - 41
Citations - 585
Matthew R. Garnett is an academic researcher from University of Cambridge. The author has contributed to research in topics: Intracranial pressure & Normal pressure hydrocephalus. The author has an hindex of 11, co-authored 41 publications receiving 394 citations. Previous affiliations of Matthew R. Garnett include Necker-Enfants Malades Hospital.
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Journal ArticleDOI
Injuries to Inferior Vermis and Dentate Nuclei Predict Poor Neurological and Neuropsychological Outcome in Children With Malignant Posterior Fossa Tumors
Stéphanie Puget,Nathalie Boddaert,Delphine Viguier,Virginie Kieffer,C. Bulteau,Matthew R. Garnett,Matthew R. Garnett,Delphine Callu,Christian Sainte-Rose,Chantal Kalifa,Georges Dellatolas,Jacques Grill +11 more
TL;DR: The correlations between the anatomical damage and the neurological/neuropsychological deficits in children with a malignant PFT are defined.
Journal ArticleDOI
A map of transcriptional heterogeneity and regulatory variation in human microglia.
Adam Young,Adam Young,Natsuhiko Kumasaka,Fiona Calvert,Timothy R. Hammond,Timothy R. Hammond,Andrew J Knights,Nikolaos Panousis,Jun Sung Park,Jeremy Schwartzentruber,Jimmy Z. Liu,Kousik Kundu,Michael Segel,Natalia A. Murphy,Christopher E McMurran,Harry Bulstrode,Jason Correia,Karol P. Budohoski,Alexis J Joannides,Mathew R. Guilfoyle,Rikin A. Trivedi,Ramez W. Kirollos,Robert H. Morris,Matthew R. Garnett,Ivan Timofeev,Ibrahim Jalloh,Katherine Holland,Richard Mannion,Richard Mair,Colin Watts,Stephen J. Price,Peter J. Kirkpatrick,Thomas Santarius,Edward Mountjoy,Maya Ghoussaini,Nicole Soranzo,Omer Ali Bayraktar,Beth Stevens,Beth Stevens,Peter J. Hutchinson,Robin J.M. Franklin,Daniel J. Gaffney +41 more
TL;DR: In this paper, gene expression variation in primary human microglia isolated from 141 patients undergoing neurosurgery was profiled using expression quantitative trait loci (eQTL) mapping.
Posted ContentDOI
A map of transcriptional heterogeneity and regulatory variation in human microglia
Adam Mh Young,Natsuhiko Kumasaka,Fiona Calvert,Timothy R. Hammond,Andrew J Knights,Nikolaos Panousis,Jeremy Schwartzentruber,Jimmy Z. Liu,Kousik Kundu,Michael Segel,Natalia A. Murphy,Christopher E McMurran,Harry Bulstrode,Jason Correia,Karol P. Budohoski,Alexis J Joannides,Mathew R. Guilfoyle,Rikin A. Trivedi,Ramez W. Kirollos,Robert H. Morris,Matthew R. Garnett,Helen M Fernandes,Ivan Timofeev,Ibrahim Jalloh,Katherine Holland,Richard Mannion,Richard Mair,Colin Watts,Stephen J. Price,Peter J. Kirkpatrick,Thomas Santarius,Nicole Soranzo,Beth Stevens,Peter J. Hutchinson,Robin J.M. Franklin,Daniel J. Gaffney +35 more
TL;DR: This study provides the first population-scale transcriptional map of a critically important cell for neurodegenerative disorders and fine-map candidate causal variants at risk loci for Alzheimer’s disease.
Journal ArticleDOI
Continuous multimodality monitoring in children after traumatic brain injury-preliminary experience
Adam Young,Joseph Donnelly,Marek Czosnyka,Marek Czosnyka,Ibrahim Jalloh,Xiuyun Liu,Marcel J. H. Aries,Helen M Fernandes,Matthew R. Garnett,Piotr Smielewski,Peter J. Hutchinson,Shruti Agrawal +11 more
TL;DR: Evidence that multi-modality monitoring may be useful in pediatric TBI with ICP, deviation of CPP from CPPopt, and PRx correlating with patient outcome is provided.
Journal ArticleDOI
Changes in elemental concentrations are associated with early stages of apoptosis in human monocyte-macrophages exposed to oxidized low-density lipoprotein: an X-ray microanalytical study.
Jeremy N. Skepper,Ioannis Karydis,Matthew R. Garnett,Laszlo Hegyi,Simon J. Hardwick,Alice Warley,Malcolm J. Mitchinson,Nat R.B. Cary +7 more
TL;DR: This is the first demonstration of early perturbations of ion homeostasis in monocyte–macrophages exposed to concentrations of oxidized LDL known to cause apoptosis.