I
Ingrid B. Borecki
Researcher at Washington University in St. Louis
Publications - 20
Citations - 7474
Ingrid B. Borecki is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: FTO gene & Genome-wide association study. The author has an hindex of 19, co-authored 20 publications receiving 7007 citations. Previous affiliations of Ingrid B. Borecki include Regeneron.
Papers
More filters
Journal ArticleDOI
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
Elizabeth K. Speliotes,Elizabeth K. Speliotes,Cristen J. Willer,Sonja I. Berndt,Keri L. Monda,Gudmar Thorleifsson,Anne U. Jackson,Hana Lango Allen,Cecilia M. Lindgren,Jian'an Luan,Reedik Maegi,Joshua C. Randall,Sailaja Vedantam,Thomas W. Winkler,Lu Qi,Lu Qi,Tsegaselassie Workalemahu,Iris M. Heid,Valgerdur Steinthorsdottir,Heather M. Stringham,Michael N. Weedon,Eleanor Wheeler,Andrew R. Wood,Teresa Ferreira,Robert J. Weyant,Ayellet V. Segrè,Ayellet V. Segrè,Karol Estrada,Liming Liang,James Nemesh,James Nemesh,Ju-Hyun Park,Stefan Gustafsson,Tuomas O. Kilpelaenen,Jian Yang,Nabila Bouatia-Naji,Nabila Bouatia-Naji,Tõnu Esko,Mary F. Feitosa,Zoltán Kutalik,Massimo Mangino,Soumya Raychaudhuri,Soumya Raychaudhuri,Soumya Raychaudhuri,André Scherag,Albert V. Smith,Ryan P. Welch,Jing Hua Zhao,Katja K.H. Aben,Devin Absher,Najaf Amin,Anna L. Dixon,Eva Fisher,Nicole L. Glazer,Michael E. Goddard,Nancy L. Heard-Costa,Volker Hoesel,Jouke-Jan Hottenga,Åsa Johansson,Åsa Johansson,Toby Johnson,Shamika Ketkar,Claudia Lamina,Shengxu Li,Miriam F. Moffatt,Richard H. Myers,Narisu Narisu,John R. B. Perry,Marjolein Peters,Michael Preuss,Samuli Ripatti,Fernando Rivadeneira,Camilla H. Sandholt,Laura J. Scott,Nicholas J. Timpson,Jonathan Tyrer,Sophie van Wingerden,Richard M. Watanabe,Charles C. White,Fredrik Wiklund,Christina Barlassina,Daniel I. Chasman,Daniel I. Chasman,Mark E. Cooper,John-Olov Jansson,Robert Lawrence,Niina Pellikka,Inga Prokopenko,Jianxin Shi,Elisabeth Thiering,Helene Alavere,Maria Teresa Sciarrone Alibrandi,Peter Almgren,Alice M. Arnold,Thor Aspelund,Larry D. Atwood,Beverley Balkau,Anthony J. Balmforth,Amanda J. Bennett,Yoav Ben-Shlomo,Richard N. Bergman,Sven Bergmann,Heike Biebermann,Alexandra I. F. Blakemore,Tanja Boes,Lori L. Bonnycastle,Stefan R. Bornstein,Morris Brown,Thomas A. Buchanan,Fabio Busonero,Harry Campbell,Francesco P. Cappuccio,Christine Cavalcanti-Proença,Christine Cavalcanti-Proença,Yii-Der Ida Chen,Chih-Mei Chen,Peter S. Chines,Robert Clarke,Lachlan J. M. Coin,John M. C. Connell,Ian N. M. Day,Martin den Heijer,Jubao Duan,Shah Ebrahim,Paul Elliott,Roberto Elosua,Gudny Eiriksdottir,Michael R. Erdos,Johan G. Eriksson,Maurizio F. Facheris,Stephan B. Felix,Pamela Fischer-Posovszky,Aaron R. Folsom,Aaron R. Folsom,Nele Friedrich,Nelson B. Freimer,Mao Fu,Stefan Gaget,Stefan Gaget,Pablo V. Gejman,Eco J. C. de Geus,Christian Gieger,Anette P. Gjesing,Anuj Goel,Philippe Goyette,Harald Grallert,Juergen Graessler,Danielle M. Greenawalt,Christopher J. Groves,Vilmundur Gudnason,Candace Guiducci,Anna-Liisa Hartikainen,Neelam Hassanali,Alistair S. Hall,Aki S. Havulinna,Caroline Hayward,Andrew C. Heath,Christian Hengstenberg,Andrew A. Hicks,Anke Hinney,Albert Hofman,Georg Homuth,Jennie Hui,Wilmar Igl,Carlos Iribarren,Carlos Iribarren,Bo Isomaa,Kevin B. Jacobs,Ivonne Jarick,Elizabeth S. Jewell,Ulrich John,Torben Jørgensen,Pekka Jousilahti,Antti Jula,Marika Kaakinen,Eero Kajantie,Lee M. Kaplan,Sekar Kathiresan,Johannes Kettunen,Leena Kinnunen,Joshua W. Knowles,Ivana Kolcic,Inke R. Koenig,Seppo Koskinen,Peter Kovacs,Johanna Kuusisto,Peter Kraft,Kirsti Kvaløy,Jaana Laitinen,Olivier Lantieri,Chiara Lanzani,Lenore J. Launer,Cécile Lecoeur,Cécile Lecoeur,Terho Lehtimaeki,Guillaume Lettre,Guillaume Lettre,Jianjun Liu,Marja-Liisa Lokki,Mattias Lorentzon,Robert Luben,Barbara Ludwig,Paolo Manunta,Diana Marek,Michel Marre,Nicholas G. Martin,Wendy L. McArdle,Anne McCarthy,Barbara McKnight,Thomas Meitinger,Olle Melander,David Meyre,David Meyre,Kristian Midthjell,Grant W. Montgomery,Mario A. Morken,Andrew P. Morris,Rosanda Mulić,Julius S. Ngwa,Mari Nelis,Mari Nelis,Matt Neville,Dale R. Nyholt,Christopher J. O'Donnell,Stephen O'Rahilly,Ken K. Ong,Ben A. Oostra,Guillaume Paré,Alex N. Parker,Markus Perola,Irene Pichler,Kirsi H. Pietilaeinen,Carl G. P. Platou,Ozren Polasek,Anneli Pouta,Suzanne Rafelt,Olli T. Raitakari,Nigel W. Rayner,Martin Ridderstråle,Winfried Rief,Aimo Ruokonen,Neil Robertson,Peter Rzehak,Veikko Salomaa,Alan R. Sanders,Manjinder S. Sandhu,Manjinder S. Sandhu,Serena Sanna,Jouko Saramies,Markku J. Savolainen,Susann Scherag,Sabine Schipf,Stefan Schreiber,Heribert Schunkert,Kaisa Silander,Juha Sinisalo,David S. Siscovick,Jan Smit,Nicole Soranzo,Nicole Soranzo,Ulla Sovio,Jonathan Stephens,Jonathan Stephens,Ida Surakka,Amy J. Swift,Mari-Liis Tammesoo,Jean-Claude Tardif,Jean-Claude Tardif,Maris Teder-Laving,Tanya M. Teslovich,John R. Thompson,John R. Thompson,Brian Thomson,Anke Toenjes,Tiinamaija Tuomi,Joyce B. J. van Meurs,Gert-Jan B. van Ommen,Vincent Vatin,Vincent Vatin,Jorma S. A. Viikari,Jorma S. A. Viikari,Sophie Visvikis-Siest,Veronique Vitart,Carla I. G. Vogel,Benjamin F. Voight,Lindsay L. Waite,Henri Wallaschofski,G. Bragi Walters,Elisabeth Widen,Susanna Wiegand,Sarah H. Wild,Gonneke Willemsen,Daniel R. Witte,Jacqueline C. M. Witteman,Jianfeng Xu,Qunyuan Zhang,Lina Zgaga,Andreas Ziegler,Paavo Zitting,John Beilby,I. Sadaf Farooqi,Johannes Hebebrand,Heikki V. Huikuri,Alan James,Mika Kaehoenen,Douglas F. Levinson,Fabio Macciardi,Fabio Macciardi,Markku S. Nieminen,Claes Ohlsson,Lyle J. Palmer,Paul M. Ridker,Paul M. Ridker,Michael Stumvoll,Jacques S. Beckmann,Heiner Boeing,Eric Boerwinkle,Dorret I. Boomsma,Mark J. Caulfield,Stephen J. Chanock,Francis S. Collins,L. Adrienne Cupples,George Davey Smith,Jeanette Erdmann,Philippe Froguel,Philippe Froguel,Philippe Froguel,Henrik Greonberg,Ulf Gyllensten,Per Hall,Torben Hansen,Tamara B. Harris,Andrew T. Hattersley,Richard B. Hayes,Joachim Heinrich,Frank B. Hu,Frank B. Hu,Kristian Hveem,Thomas Illig,Marjo-Riitta Järvelin,Marjo-Riitta Järvelin,Jaakko Kaprio,Fredrik Karpe,Kay-Tee Khaw,Lambertus A. Kiemeney,Heiko Krude,Markku Laakso,Debbie A Lawlor,Andres Metspalu,Patricia B. Munroe,Willem H. Ouwehand,Willem H. Ouwehand,Willem H. Ouwehand,Oluf Pedersen,Oluf Pedersen,Brenda W.J.H. Penninx,Brenda W.J.H. Penninx,Annette Peters,Peter P. Pramstaller,Thomas Quertermous,Thomas Reinehr,Aila Rissanen,Igor Rudan,Igor Rudan,Nilesh J. Samani,Peter Schwarz,Alan R. Shuldiner,Tim D. Spector,Jaakko Tuomilehto,Manuela Uda,André G. Uitterlinden,Timo T. Valle,Martin Wabitsch,Gerard Waeber,Nicholas J. Wareham,Hugh Watkins,James F. Wilson,Alan F. Wright,M. Carola Zillikens,Nilanjan Chatterjee,Steven A. McCarroll,Shaun Purcell,Eric E. Schadt,Peter M. Visscher,Themistocles L. Assimes,Ingrid B. Borecki,Panos Deloukas,Caroline S. Fox,Leif Groop,Talin Haritunians,David J. Hunter,David J. Hunter,Robert C. Kaplan,Karen L. Mohlke,Jeffrey R. O'Connell,Leena Peltonen,David Schlessinger,David P. Strachan,Cornelia M. van Duijn,H-Erich Wichmann,Timothy M. Frayling,Unnur Thorsteinsdottir,Unnur Thorsteinsdottir,Gonçalo R. Abecasis,Inês Barroso,Inês Barroso,Michael Boehnke,Kari Stefansson,Kari Stefansson,Kari E. North,Mark I. McCarthy,Joel N. Hirschhorn,Erik Ingelsson,Ruth J. F. Loos +413 more
TL;DR: Genetic loci associated with body mass index map near key hypothalamic regulators of energy balance, and one of these loci is near GIPR, an incretin receptor, which may provide new insights into human body weight regulation.
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
Elizabeth K. Speliotes,Cristen J. Willer,Sonja I. Berndt,Keri L. Monda,Gudmar Thorleifsson,Anne U. Jackson,H Lango Allen,Cecilia M. Lindgren,Jian'an Luan,Reedik Mägi,Joshua C. Randall,Sailaja Vedantam,Thomas W. Winkler,Lu Qi,Tsegaselassie Workalemahu,Iris M. Heid,Valgerdur Steinthorsdottir,Heather M. Stringham,Michael N. Weedon,Eleanor Wheeler,Andrew R. Wood,Teresa Ferreira,Robert J. Weyant,Ayellet V. Segrè,K. Estrada,Liming Liang,James Nemesh,Ju-Hyun Park,Stefan Gustafsson,Tuomas O. Kilpeläinen,Jian Yang,Nabila Bouatia-Naji,Tõnu Esko,Mary F. Feitosa,Zoltán Kutalik,Massimo Mangino,Soumya Raychaudhuri,André Scherag,Albert V. Smith,Ryan P. Welch,Jing Hua Zhao,Katja K.H. Aben,Devin Absher,Najaf Amin,Anna L. Dixon,Eva Fisher,Nicole L. Glazer,Michael E. Goddard,Nancy L. Heard-Costa,Volker Hoesel,Jouke-Jan Hottenga,Åsa Johansson,Toby Johnson,Shamika Ketkar,Claudia Lamina,Shengxu Li,MF Moffatt,Richard H. Myers,Narisu Narisu,John R. B. Perry,Maire Peters,Michael Preuss,Samuli Ripatti,Fernando Rivadeneira,Camilla H. Sandholt,Laura J. Scott,Nicholas J. Timpson,Jonathan Tyrer,S. van Wingerden,Richard M. Watanabe,Charles L. White,Fredrik Wiklund,Cristina Barlassina,Daniel I. Chasman,Mark E. Cooper,John-Olov Jansson,Robert W. Lawrence,Niina Pellikka,Inga Prokopenko,Jianxin Shi,Elisabeth Thiering,Helene Alavere,Maria Teresa Sciarrone Alibrandi,Peter Almgren,Andreas Arnold,Thor Aspelund,Larry D. Atwood,Beverley Balkau,Anthony J. Balmforth,Amanda J. Bennett,Yoav Ben-Shlomo,Richard N. Bergman,Sven Bergmann,Heike Biebermann,Alexandra I. F. Blakemore,Tanja Boes,Lori L. Bonnycastle,Stefan R. Bornstein,Michael Brown,Thomas A. Buchanan,Fabio Busonero,Harry Campbell,Francesco P. Cappuccio,Christine Cavalcanti-Proença,Y. D. Chen,C. M. Chen,Peter S. Chines,Robert Clarke,Lachlan J. M. Coin,John M. C. Connell,Ian N.M. Day,M. den Heijer,Jubao Duan,Shah Ebrahim,Paul Elliott,Roberto Elosua,G. Eiriksdottir,Mike Erdos,Johan G. Eriksson,Maurizio Facheris,Stephan B. Felix,Pamela Fischer-Posovszky,Aaron R. Folsom,Nele Friedrich,Nelson B. Freimer,Mao Fu,Stéphane Gaget,Pablo V. Gejman,Eco J. C. de Geus,Christian Gieger,Anette P. Gjesing,Anuj Goel,Philippe Goyette,Harald Grallert,Jürgen Grässler,Danielle M. Greenawalt,C J Groves,Vilmundur Gudnason,Candace Guiducci,A.-L. Hartikainen,N Hassanali,Alistair S. Hall,Aki S. Havulinna,Caroline Hayward,Andrew C. Heath,Christian Hengstenberg,Andrew A. Hicks,Anke Hinney,Albert Hofman,G. Homuth,Jennie Hui,Wilmar Igl,Carlos Iribarren,Bo Isomaa,Kevin B. Jacobs,Ivonne Jarick,Elizabeth S. Jewell,Ulrich John,Torben Jørgensen,P. Jousilahti,A. Jula,Marika Kaakinen,Eero Kajantie,Lee M. Kaplan,Sekar Kathiresan,Johannes Kettunen,Leena Kinnunen,Joshua W. Knowles,Ivana Kolcic,Inke R. König,Seppo Koskinen,Peter Kovacs,Johanna Kuusisto,Peter Kraft,Kirsti Kvaløy,Jaana Laitinen,Olivier Lantieri,Chiara Lanzani,Lenore J. Launer,Cécile Lecoeur,Terho Lehtimäki,Guillaume Lettre,Jianjun Liu,Marja-Liisa Lokki,Mattias Lorentzon,Robert Luben,Barbara Ludwig,Paolo Manunta,Diana Marek,Michel Marre,Nicholas G. Martin,Wendy L. McArdle,Alun D. McCarthy,Barbara McKnight,Thomas Meitinger,Olle Melander,David Meyre,Kristian Midthjell,Grant W. Montgomery,M. A. Morken,Andrew P. Morris,Rosanda Mulić,Julius S. Ngwa,Mari Nelis,Matt Neville,Dale R. Nyholt,Christopher J. O'Donnell,Stephen O'Rahilly,Ken K. Ong,Ben A. Oostra,Guillaume Paré,Alex N. Parker,Markus Perola,Irene Pichler,Kirsi H. Pietiläinen,Carl Platou,Ozren Polasek,A Pouta,Suzanne Rafelt,Olli T. Raitakari,Nigel W. Rayner,Martin Ridderstråle,Winfried Rief,Aimo Ruokonen,Neil R. Robertson,Peter Rzehak,Veikko Salomaa,Alan R. Sanders,Manjinder S. Sandhu,Serena Sanna,Jouko Saramies,Markku J. Savolainen,S. Scherag,Sabine Schipf,Stefan Schreiber,Heribert Schunkert,Kaisa Silander,Juha Sinisalo,David S. Siscovick,J.H. Smit,Nicole Soranzo,Ulla Sovio,J. Stephens,Ida Surakka,Amy J. Swift,M. L. Tammesoo,Jean-Claude Tardif,Maris Teder-Laving,Tanya M. Teslovich,John R. Thompson,Brian Thomson,A Tönjes,Tiinamaija Tuomi,J.B. van Meurs,G.J.B. van Ommen,Vincent Vatin,Jorma Viikari,Sophie Visvikis-Siest,Veronique Vitart,Charlotte Vogel,Benjamin F. Voight,Lindsay L. Waite,Henri Wallaschofski,G B Walters,E. Widen,Susanna Wiegand,Sarah H. Wild,Gonneke Willemsen,Daniel R. Witte,Jacqueline C. M. Witteman,Jianfeng Xu,Qunyuan Zhang,Lina Zgaga,Andreas Ziegler,P. Zitting,John Beilby,I S Farooqi,Johannes Hebebrand,Heikki V. Huikuri,Alan L. James,Mika Kähönen,Douglas F. Levinson,Fabio Macciardi,Markku S. Nieminen,Claes Ohlsson,Lyle J. Palmer,Paul M. Ridker,Michael Stumvoll,Jacques S. Beckmann,H. Boeing,Eric Boerwinkle,Dorret I. Boomsma,Mark J. Caulfield,Stephen J. Chanock,Francis S. Collins,L. A. Cupples,George Davey Smith,Jeanette Erdmann,Philippe Froguel,Henrik Grönberg,Ulf Gyllensten,Per Hall,Torben Hansen,Tamara B. Harris,Andrew T. Hattersley,Richard B. Hayes,Joachim Heinrich,Frank B. Hu,Kristian Hveem,Thomas Illig,Marjo-Riitta Järvelin,Jaakko Kaprio,Fredrik Karpe,Kay-Tee Khaw,Lambertus A. Kiemeney,Heiko Krude,Markku Laakso,Debbie A Lawlor,Andres Metspalu,Patricia B. Munroe,Willem H. Ouwehand,Oluf Pedersen,Brenda W.J.H. Penninx,Annette Peters,Peter P. Pramstaller,Thomas Quertermous,Thomas Reinehr,A. Rissanen,Igor Rudan,Nilesh J. Samani,Peter Schwarz,Alan R. Shuldiner,Tim D. Spector,Jaakko Tuomilehto,Manuela Uda,André G. Uitterlinden,Valle Tt,Martin Wabitsch,G. Waeber,Nicholas J. Wareham,Hugh Watkins,James F. Wilson,Alan F. Wright,M. C. Zillikens,Nilanjan Chatterjee,Steven A. McCarroll,Shaun Purcell,Eric E. Schadt,Peter M. Visscher,Themistocles L. Assimes,Ingrid B. Borecki,Panos Deloukas,Caroline S. Fox,Leif Groop,Talin Haritunians,David J. Hunter,Robert C. Kaplan,Karen L. Mohlke,Jeffrey R. O'Connell,Leena Peltonen,David Schlessinger,David P. Strachan,C M van Duijn,H. E. Wichmann,Timothy M. Frayling,Unnur Thorsteinsdottir,Gonçalo R. Abecasis,Inês Barroso,Michael Boehnke,Kari Stefansson,Kari E. North,Mark I. McCarthy,Joel N. Hirschhorn,Erik Ingelsson,Ruth J. F. Loos +374 more
TL;DR: 18 new loci associated with body mass index are identified, one of which includes a copy number variant near GPRC5B, and genes in other newly associated loci may provide new insights into human body weight regulation.
Journal ArticleDOI
Physical activity attenuates the influence of FTO variants on obesity risk: A meta-analysis of 218,166 adults and 19,268 children
Tuomas O. Kilpeläinen,Lu Qi,Soren Brage,Stephen J. Sharp,Emily Sonestedt,Ellen W. Demerath,Tariq Ahmad,Samia Mora,Marika Kaakinen,Camilla H. Sandholt,Christina Holzapfel,Christine S. Autenrieth,Elina Hyppönen,Stéphane Cauchi,Meian He,Zoltán Kutalik,Meena Kumari,Alena Stančáková,Karina Meidtner,Beverley Balkau,Jonathan T. Tan,Massimo Mangino,Nicholas J. Timpson,Yiqing Song,M. Carola Zillikens,Kathleen A. Jablonski,Melissa E. Garcia,Stefan Johansson,Jennifer L. Bragg-Gresham,Ying Wu,Jana V. van Vliet-Ostaptchouk,N. Charlotte Onland-Moret,Esther Zimmermann,Natalia V. Rivera,Toshiko Tanaka,Heather M. Stringham,Günther Silbernagel,Stavroula Kanoni,Mary F. Feitosa,Soren Snitker,Jonatan R. Ruiz,Jeffery Metter,María Teresa Martínez Larrad,Mustafa Atalay,Maarit Hakanen,Najaf Amin,Christine Cavalcanti-Proença,Anders Grøntved,Göran Hallmans,John-Olov Jansson,Johanna Kuusisto,Mika Kähönen,Pamela L. Lutsey,John J. Nolan,Luigi Palla,Oluf Pedersen,Louis Pérusse,Frida Renström,Robert A. Scott,Dmitry Shungin,Ulla Sovio,Tuija Tammelin,Tapani Rönnemaa,Timo A. Lakka,Matti Uusitupa,Manuel Serrano Ríos,Luigi Ferrucci,Claude Bouchard,Aline Meirhaeghe,Mao Fu,Mark Walker,Ingrid B. Borecki,George Dedoussis,Andreas Fritsche,Claes Ohlsson,Michael Boehnke,Stefania Bandinelli,Cornelia M. van Duijn,Shah Ebrahim,Debbie A Lawlor,Vilmundur Gudnason,Tamara B. Harris,Thorkild I. A. Sørensen,Karen L. Mohlke,Albert Hofman,André G. Uitterlinden,Jaakko Tuomilehto,Terho Lehtimäki,Olli T. Raitakari,Bo Isomaa,Pål R. Njølstad,Jose C. Florez,Simin Liu,Andy R Ness,Tim D. Spector,E. Shyong Tai,Philippe Froguel,Heiner Boeing,Markku Laakso,Michael Marmot,Sven Bergmann,Chris Power,Kay-Tee Khaw,Daniel I. Chasman,Paul M. Ridker,Torben Hansen,Keri L. Monda,Thomas Illig,Marjo-Riitta Järvelin,Nicholas J. Wareham,Frank B. Hu,Leif Groop,Marju Orho-Melander,Ulf Ekelund,Paul W. Franks,Ruth J. F. Loos +115 more
TL;DR: In this paper, a meta-analysis of data from 45 studies of adults and nine studies of children and adolescents was conducted to confirm or refute unambiguously whether physical activity attenuates the association of FTO with obesity risk.
Journal ArticleDOI
FTO genotype is associated with phenotypic variability of body mass index
Jian Yang,Jian Yang,Ruth J. F. Loos,Ruth J. F. Loos,Joseph E. Powell,Joseph E. Powell,Sarah E. Medland,Elizabeth K. Speliotes,Daniel I. Chasman,Lynda M. Rose,Gudmar Thorleifsson,Valgerdur Steinthorsdottir,Reedik Mägi,Reedik Mägi,Lindsay L. Waite,Albert V. Smith,Laura M. Yerges-Armstrong,Keri L. Monda,David Hadley,Anubha Mahajan,Guo Li,Karen Kapur,Karen Kapur,Veronique Vitart,Jennifer E. Huffman,Sophie R. Wang,Sophie R. Wang,Cameron D. Palmer,Cameron D. Palmer,Tõnu Esko,Krista Fischer,Jing Hua Zhao,Ayse Demirkan,Aaron Isaacs,Mary F. Feitosa,Jian'an Luan,Nancy L. Heard-Costa,Charles S. White,Anne U. Jackson,Michael Preuss,Andreas Ziegler,Joel Eriksson,Zoltán Kutalik,Francesca Frau,Ilja M. Nolte,Jana V. van Vliet-Ostaptchouk,Jouke-Jan Hottenga,Kevin B. Jacobs,Niek Verweij,Anuj Goel,Carolina Medina-Gomez,Karol Estrada,Jennifer L. Bragg-Gresham,Serena Sanna,Carlo Sidore,Carlo Sidore,Jonathan Tyrer,Alexander Teumer,Inga Prokopenko,Massimo Mangino,Cecilia M. Lindgren,Themistocles L. Assimes,Alan R. Shuldiner,Alan R. Shuldiner,Jennie Hui,John Beilby,Wendy L. McArdle,Per Hall,Talin Haritunians,Lina Zgaga,Lina Zgaga,Ivana Kolcic,Ozren Polasek,Tatijana Zemunik,Ben A. Oostra,M. Juhani Junttila,Henrik Grönberg,Stefan Schreiber,Annette Peters,Andrew A. Hicks,Jonathan Stephens,Jonathan Stephens,Nicola S. Foad,Nicola S. Foad,Jaana Laitinen,Anneli Pouta,Anneli Pouta,Marika Kaakinen,Gonneke Willemsen,Jacqueline M. Vink,Sarah H Wild,Gerjan Navis,Folkert W. Asselbergs,Georg Homuth,Ulrich John,Carlos Iribarren,Tamara B. Harris,Lenore J. Launer,Vilmundur Gudnason,Jeffrey R. O'Connell,Eric Boerwinkle,Gemma Cadby,Lyle J. Palmer,Alan James,Arthur W. Musk,Erik Ingelsson,Bruce M. Psaty,Bruce M. Psaty,Jacques S. Beckmann,Gerard Waeber,Peter Vollenweider,Caroline Hayward,Alan F. Wright,Igor Rudan,Igor Rudan,Leif Groop,Andres Metspalu,Kay-Tee Khaw,Cornelia M. van Duijn,Ingrid B. Borecki,Michael A. Province,Nicholas J. Wareham,Jean-Claude Tardif,Heikki V. Huikuri,L. Adrienne Cupples,Larry D. Atwood,Caroline S. Fox,Michael Boehnke,Francis S. Collins,Karen L. Mohlke,Jeanette Erdmann,Heribert Schunkert,Christian Hengstenberg,Klaus Stark,Mattias Lorentzon,Claes Ohlsson,Daniele Cusi,Jan A. Staessen,Jan A. Staessen,Melanie M. van der Klauw,Peter P. Pramstaller,Sekar Kathiresan,Sekar Kathiresan,Sekar Kathiresan,Jennifer Jolley,Jennifer Jolley,Samuli Ripatti,Samuli Ripatti,Samuli Ripatti,Marjo-Riitta Järvelin,Marjo-Riitta Järvelin,Marjo-Riitta Järvelin,Eco J. C. de Geus,Dorret I. Boomsma,Brenda W. J. H. Penninx,James F. Wilson,Harry Campbell,Stephen J. Chanock,Pim van der Harst,Anders Hamsten,Hugh Watkins,Albert Hofman,Jacqueline C. M. Witteman,M. Carola Zillikens,André G. Uitterlinden,Fernando Rivadeneira,Lambertus A. Kiemeney,Sita H. Vermeulen,Gonçalo R. Abecasis,David Schlessinger,Sabine Schipf,Michael Stumvoll,Anke Tönjes,Tim D. Spector,Kari E. North,Guillaume Lettre,Mark I. McCarthy,Sonja I. Berndt,Andrew C. Heath,Pamela A. F. Madden,Dale R. Nyholt,Grant W. Montgomery,Nicholas G. Martin,Barbara McKnight,David P. Strachan,William G. Hill,Harold Snieder,Paul M. Ridker,Unnur Thorsteinsdottir,Unnur Thorsteinsdottir,Kari Stefansson,Kari Stefansson,Timothy M. Frayling,Joel N. Hirschhorn,Joel N. Hirschhorn,Michael E. Goddard,Michael E. Goddard,Peter M. Visscher,Peter M. Visscher +198 more
TL;DR: The authors performed a meta-analysis of genome-wide association studies of phenotypic variation using ∼170,000 samples on height and body mass index (BMI) in human populations.
Journal ArticleDOI
Genome-Wide Association Study for Coronary Artery Calcification With Follow-Up in Myocardial Infarction
Christopher J. O'Donnell,Christopher J. O'Donnell,Maryam Kavousi,Albert V. Smith,Sharon L.R. Kardia,Sharon L.R. Kardia,Mary F. Feitosa,Shih-Jen Hwang,Yan V. Sun,Michael A. Province,Thor Aspelund,Abbas Dehghan,Udo Hoffmann,Lawrence F. Bielak,Qunyuan Zhang,Gudny Eiriksdottir,Cornelia M. van Duijn,Caroline S. Fox,Caroline S. Fox,Mariza de Andrade,Aldi T. Kraja,Sigurdur Sigurdsson,Suzette E. Elias-Smale,Joanne M. Murabito,Lenore J. Launer,Aad van der Lugt,Sekar Kathiresan,Gabriel P. Krestin,David M. Herrington,Timothy D. Howard,Yongmei Liu,Wendy S. Post,Braxton D. Mitchell,Jeffrey R. O'Connell,Haiqing Shen,Alan R. Shuldiner,David Altshuler,David Altshuler,Roberto Elosua,Veikko Salomaa,Stephen M. Schwartz,David S. Siscovick,Benjamin F. Voight,Benjamin F. Voight,Joshua C. Bis,Nicole L. Glazer,Bruce M. Psaty,Eric Boerwinkle,Gerardo Heiss,Stefan Blankenberg,Tanja Zeller,Philipp S. Wild,Renate B. Schnabel,Arne Schillert,Andreas Ziegler,Thomas Münzel,Charles C. White,Jerome I. Rotter,Mike A. Nalls,Matthijs Oudkerk,Andrew D. Johnson,Anne B. Newman,André G. Uitterlinden,Joseph M. Massaro,Julie M. Cunningham,Tamara B. Harris,Albert Hofman,Patricia A. Peyser,Ingrid B. Borecki,L. Adrienne Cupples,Vilmundur Gudnason,Jacqueline C.M. Witteman +71 more
TL;DR: SNPs in the 9p21 and PHACTR1 gene loci were strongly associated with CAC and MI, and there is suggestive associations with both Cac and MI of SNPs in additional loci.