M
Michael R. Stratton
Researcher at Wellcome Trust Sanger Institute
Publications - 464
Citations - 162105
Michael R. Stratton is an academic researcher from Wellcome Trust Sanger Institute. The author has contributed to research in topics: Cancer & Mutation. The author has an hindex of 161, co-authored 443 publications receiving 142586 citations. Previous affiliations of Michael R. Stratton include University of Cambridge & The Breast Cancer Research Foundation.
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Journal ArticleDOI
Familial craniofacial fibrous dysplasia: absence of linkage to GNAS1 and the gene for cherubism.
TL;DR: Fibrous dysplasia usually occurs with no family history, although CFD has been shown to be inherited in an autosomal dominant fashion.
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Mutagenicity of acrylamide and glycidamide in human TP53 knock-in (Hupki) mouse embryo fibroblasts.
Lisa Hölzl-Armstrong,Jill E. Kucab,Sarah Moody,Edwin P. Zwart,Lucie Loutkotová,Lucie Loutkotová,Veronica Duffy,Mirjam Luijten,Gonçalo Gamboa da Costa,Michael R. Stratton,David H. Phillips,Volker M. Arlt +11 more
TL;DR: The results of the present study suggest that glycidamide may be involved in the development of breast, ovarian, and lung cancer.
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Erratum: Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue (Nature Genetics (2015) 47 (367-372))
Colin Cooper,Rosalind A. Eeles,David C. Wedge,Peter Van Loo,Gunes Gundem,Ludmil B. Alexandrov,Barbara Kremeyer,Adam Butler,Andy G. Lynch,Niedzica Camacho,Charles E. Massie,Jonathan Kay,Hayley J. Luxton,S. Edwards,Zsofia Kote-Jarai,Nening Dennis,Sue Merson,Daniel Leongamornlert,Jorge Zamora,Cathy Corbishley,Sarah Thomas,Serena Nik-Zainal,Manasa Ramakrishna,Sarah O’Meara,Lucy Matthews,Jeremy Clark,Rachel Hurst,Richard Mithen,Robert G. Bristow,Paul C. Boutros,Michael Fraser,Susanna L. Cooke,Keiran Raine,David Jones,Andrew Menzies,Lucy Stebbings,Jon Hinton,Jon W. Teague,Stuart McLaren,Laura Mudie,Claire Hardy,Elizabeth Anderson,Olivia Joseph,Victoria Goody,Ben Robinson,Mark Maddison,Stephen J. Gamble,Christopher Greenman,Daniel M. Berney,Steven Hazell,Naomi Livni,Cyril Fisher,Chris Ogden,Pardeep Kumar,Alan Thompson,C. R. J. Woodhouse,David Nicol,Erik Mayer,Tim Dudderidge,Nimish Shah,Vincent J. Gnanapragasam,Thierry Voet,Peter T. Campbell,Andrew Futreal,Douglas F. Easton,Anne Y. Warren,Christopher S. Foster,Michael R. Stratton,Hayley C. Whitaker,Ultan McDermott,Daniel Brewer,David E. Neal +71 more
TL;DR: In the version of this article initially published, the following two sentences were omitted from the Acknowledgments: “Sequencing was carried out at the Millard and Muriel Jacobs Genome Facility at the California Institute of Technology.”
Journal ArticleDOI
Understanding the target
TL;DR: The complicated responses of lung-cancer patients to a particular drug — gefitinib — are now less puzzling because mutations in the target gene help to explain why the treatment works in some cases but not in others.
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Refined mapping of X-linked reticulate pigmentary disorder and sequencing of candidate genes.
Lane Santos,Chao Xing,Robert B. Barnes,Lesley C. Adès,André Mégarbané,Christopher Vidal,Angela Xuereb,Patrick S. Tarpey,Raffaella Smith,Mahmoud Khazab,Cheryl Shoubridge,Michael Partington,Andrew Futreal,Michael R. Stratton,Jozef Gecz,Andrew R. Zinn +15 more
TL;DR: Sequencing of other X-linked genes outside of the linked interval failed to identify the cause of PDR but revealed a novel nonsynonymous cSNP in the GRPR gene in the Maltese population.