Ming Tsai

TL;DR: Comparative analyses show a fascinating picture of conservation and divergence, revealing large blocks of gene orthology with rodents, scattered regions with more recent gene family expansions and deletions, and segments of coding and non-coding conservation with the distant fish species Takifugu.

TL;DR: The results of the largest examination of the quality of the finished DNA sequence are presented, based on a rigorous combination of laboratory experiments and computational analysis.

TL;DR: The 78,884,754 base pairs of finished chromosome 16 sequence, representing over 99.9% of its euchromatin, revealed 880 protein-coding genes, including metallothionein, cadherin and iroquois gene families, as well as the disease genes for polycystic kidney disease and acute myelomonocytic leukaemia.

TL;DR: In this paper, the authors reported the 78,884,754 base pairs of the human chromosome 16 sequence, representing over 99.9 percent of its euchromatin, were annotated with 880 protein coding genes.

TL;DR: This work has compiled 177.7 million base pairs of highly accurate finished sequence containing 923 manually curated protein-encoding genes including the protocadherin and interleukin gene families and the first complete versions of each of the large chromosome 5 specific internal duplications.