M
Monika Pilichowska
Researcher at Tufts Medical Center
Publications - 65
Citations - 2430
Monika Pilichowska is an academic researcher from Tufts Medical Center. The author has contributed to research in topics: Transplantation & Myeloid. The author has an hindex of 20, co-authored 63 publications receiving 1905 citations. Previous affiliations of Monika Pilichowska include Tufts University & Harvard University.
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Journal ArticleDOI
Genetic and Functional Drivers of Diffuse Large B Cell Lymphoma.
Anupama Reddy,Jenny Zhang,Nicholas S. Davis,Andrea B. Moffitt,Cassandra Love,Alexander Waldrop,Sirpa Leppä,Annika Pasanen,Leo Meriranta,Marja-Liisa Karjalainen-Lindsberg,Peter Nørgaard,Mette Merete Pedersen,Anne O. Gang,Estrid Høgdall,Tayla Heavican,Waseem Gul Lone,Javeed Iqbal,Qiu Qin,Guojie Li,So Young Kim,Jane Healy,Kristy L. Richards,Yuri Fedoriw,Leon Bernal-Mizrachi,Jean L. Koff,Ashley D. Staton,Christopher R. Flowers,Ora Paltiel,Neta Goldschmidt,Maria Calaminici,Andrew Clear,John G. Gribben,Evelyn T. Nguyen,Magdalena Czader,Sarah L. Ondrejka,Angela M. B. Collie,Eric D. Hsi,Eric Tse,Rex Au-Yeung,Yok-Lam Kwong,Gopesh Srivastava,William W.L. Choi,Andrew M. Evens,Monika Pilichowska,Manju Sengar,Nishitha Reddy,Shaoying Li,Amy Chadburn,Leo I. Gordon,Elaine S. Jaffe,Shawn Levy,Rachel E. Rempel,Tiffany Tzeng,Lanie Happ,Tushar Dave,Deepthi Rajagopalan,Jyotishka Datta,David B. Dunson,Sandeep S. Dave +58 more
TL;DR: An integrative analysis of whole-exome sequencing and transcriptome sequencing in a cohort of DLBCL patients is performed to comprehensively define the landscape of 150 genetic drivers of the disease and their functional roles to identify new therapeutic opportunities in the disease.
Journal ArticleDOI
AG-221, a First-in-Class Therapy Targeting Acute Myeloid Leukemia Harboring Oncogenic IDH2 Mutations
Katharine E. Yen,Jeremy Travins,Fang Wang,Muriel D. David,Muriel D. David,Erin Artin,Kimberly Straley,Anil K. Padyana,Stefan Gross,Byron DeLaBarre,Erica Tobin,Yue Chen,Raj Nagaraja,Sung Choe,Lei Jin,Zenon D. Konteatis,Giovanni Cianchetta,Jeffrey O. Saunders,Francesco G. Salituro,Cyril Quivoron,Cyril Quivoron,Paule Opolon,Olivia Bawa,Véronique Saada,Véronique Saada,Angelo Paci,Sophie Broutin,Olivier Bernard,Olivier Bernard,Stéphane de Botton,Stéphane de Botton,Benoit S. Marteyn,Benoit S. Marteyn,Monika Pilichowska,Yingxia Xu,Cheng Fang,Fan Jiang,Wentao Wei,Shengfang Jin,Lee Silverman,Wei Liu,Hua Yang,Lenny Dang,Marion Dorsch,Virginie Penard-Lacronique,Virginie Penard-Lacronique,Scott A. Biller,Shin-San Michael Su +47 more
TL;DR: It is shown that the targeted inhibitor AG-221 suppresses the mutant IDH2 enzyme in multiple preclinical models and induces differentiation of malignant blasts, supporting its clinical development.
Journal ArticleDOI
The Genetic Basis of Hepatosplenic T-cell Lymphoma
Matthew McKinney,Andrea B. Moffitt,Philippe Gaulard,Marion Travert,Laurence de Leval,Alina Nicolae Mark Raffeld,Elaine S. Jaffe,Stefania Pittaluga,Liqiang Xi,Tayla Heavican,Javeed Iqbal,Karim Belhadj,Marie Helene Delfau-Larue,Virginie Fataccioli,Magdalena Czader,Izidore S. Lossos,Jennifer R. Chapman-Fredricks,Kristy L. Richards,Yuri Fedoriw,Sarah L. Ondrejka,Eric D. Hsi,Lawrence Low,Dennis D. Weisenburger,Wing C. Chan,Neha Mehta-Shah,Steven M. Horwitz,Leon Bernal-Mizrachi,Christopher R. Flowers,Anne W. Beaven,Mayur Parihar,Lucile Baseggio,Marie Parrens,Anne Moreau,Pierre Sujobert,Monika Pilichowska,Andrew M. Evens,Amy Chadburn,Rex Au-Yeung,Gopesh Srivastava,William W.L. Choi,John R. Goodlad,Igor Aurer,Sandra Bašić-Kinda,Randy D. Gascoyne,Nicholas S. Davis,Guojie Li,Jenny Zhang,Deepthi Rajagopalan,Anupama Reddy,Cassandra Love,Shawn Levy,Yuan Zhuang,Jyotishka Datta,David B. Dunson,Sandeep S. Dave +54 more
TL;DR: The first systematic application of whole-exome sequencing to define the genetic basis of HSTL and implicates genes including INO80 and PIK3CD in the disease and finds that mutations in STAT5B and Pik3CD activate critical signaling pathways important to cell survival in H STL.
Journal ArticleDOI
Primary hepatic carcinoid and neuroendocrine carcinoma: Clinicopathological and immunohistochemical study of five cases
TL;DR: The most useful marker to confirm the diagnosis was chromogranin A, which was cleaved to pancreastatin and chromostatin in the tumor tissue, and was more reliable than other markers of neuroendocrine differentiation.
Journal ArticleDOI
Resistance training increases muscle mitochondrial biogenesis in patients with chronic kidney disease.
Vaidyanatha S. Balakrishnan,Madhumathi Rao,Vandana Menon,Patricia L. Gordon,Monika Pilichowska,Francisco Castaneda,Carmen Castaneda-Sceppa +6 more
TL;DR: In this article, the effect of resistance exercise training on skeletal muscle mitochondrial (mt)DNA copy number and determined its association with skeletal muscle phenotype (muscle mass and strength) was examined.