Nicholas S. Davis

TL;DR: The Encyclopedia of DNA Elements project provides new insights into the organization and regulation of the authors' genes and genome, and is an expansive resource of functional annotations for biomedical research.

TL;DR: An integrative analysis of whole-exome sequencing and transcriptome sequencing in a cohort of DLBCL patients is performed to comprehensively define the landscape of 150 genetic drivers of the disease and their functional roles to identify new therapeutic opportunities in the disease.

TL;DR: Both breast cancer associated fusion transcripts identified in this study involve membrane proteins (SCNN1A-TNFRSF1A and CTSD-IFITM10), which raises the possibility that they could be breast cancer-specific cell surface markers.

TL;DR: The first systematic application of whole-exome sequencing to define the genetic basis of HSTL and implicates genes including INO80 and PIK3CD in the disease and finds that mutations in STAT5B and Pik3CD activate critical signaling pathways important to cell survival in H STL.

TL;DR: A high-confidence set of independently validated genes differentially expressed between schizophrenia and control patients in the anterior cingulate cortex are highlighted and integrated transcriptional changes with untargeted metabolite profiling are integrated.