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Natalia Borruel
Researcher at Autonomous University of Barcelona
Publications - 56
Citations - 9781
Natalia Borruel is an academic researcher from Autonomous University of Barcelona. The author has contributed to research in topics: Inflammatory bowel disease & Ulcerative colitis. The author has an hindex of 21, co-authored 47 publications receiving 8089 citations. Previous affiliations of Natalia Borruel include Carlos III Health Institute.
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Journal ArticleDOI
Enterotypes of the human gut microbiome
Manimozhiyan Arumugam,Jeroen Raes,Eric Pelletier,Denis Le Paslier,Takuji Yamada,Daniel R. Mende,Gabriel Fernandes,Julien Tap,Thomas Brüls,Jean-Michel Batto,Marcelo Bertalan,Natalia Borruel,Francesc Casellas,Leyden Fernández,Laurent Gautier,Torben Hansen,Masahira Hattori,Tetsuya Hayashi,Michiel Kleerebezem,Ken Kurokawa,Marion Leclerc,Florence Levenez,Chaysavanh Manichanh,H. Bjørn Nielsen,Trine Nielsen,Nicolas Pons,Julie Poulain,Junjie Qin,Thomas Sicheritz-Pontén,Sebastian Tims,David Torrents,Edgardo Ugarte,Erwin G. Zoetendal,Jun Wang,Francisco Guarner,Oluf Pedersen,Willem M. de Vos,Søren Brunak,Joël Doré,Jean Weissenbach,S. Dusko Ehrlich,Peer Bork +41 more
TL;DR: Three robust clusters (referred to as enterotypes hereafter) are identified that are not nation or continent specific and confirmed in two published, larger cohorts, indicating that intestinal microbiota variation is generally stratified, not continuous.
Journal ArticleDOI
The gut microbiota in IBD.
TL;DR: Dysbiosis (that is, abnormal microbiota composition) and decreased complexity of the gut microbial ecosystem are common features in patients with Crohn's disease or ulcerative colitis, and whether such changes are a cause or a consequence of the disease remains to be elucidated.
Journal ArticleDOI
Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes
H. Bjørn Nielsen,Mathieu Almeida,Agnieszka S. Juncker,Simon Rasmussen,Junhua Li,Shinichi Sunagawa,Damian R. Plichta,Laurent Gautier,Anders Gorm Pedersen,Eric Pelletier,Ida Bonde,Trine Nielsen,Chaysavanh Manichanh,Manimozhiyan Arumugam,Jean-Michel Batto,Marcelo B Quintanilha dos Santos,Nikolaj Blom,Natalia Borruel,Kristoffer Sølvsten Burgdorf,Fouad Boumezbeur,Francesc Casellas,Joël Doré,Piotr Dworzynski,Francisco Guarner,Torben Hansen,Falk Hildebrand,Rolf Sommer Kaas,Sean Kennedy,Karsten Kristiansen,Jens Roat Kultima,Pierre Leonard,Florence Levenez,Ole Lund,Bouziane Moumen,Denis Le Paslier,Nicolas Pons,Oluf Pedersen,Edi Prifti,Junjie Qin,Jeroen Raes,Søren J. Sørensen,Julien Tap,Sebastian Tims,David W. Ussery,Takuji Yamada,Pierre Renault,Thomas Sicheritz-Pontén,Peer Bork,Jun Wang,Søren Brunak,S. Dusko Ehrlich +50 more
TL;DR: This work presents a method, based on binning co-abundant genes across a series of metagenomic samples, that enables comprehensive discovery of new microbial organisms, viruses and co-inherited genetic entities and aids assembly of microbial genomes without the need for reference sequences.
Journal ArticleDOI
A microbial signature for Crohn ’ s disease
Victoria Pascal,Marta Pozuelo,Natalia Borruel,Francesc Casellas,David Campos,Alba Santiago,Xavier Martinez,Encarna Varela,Guillaume Sarrabayrouse,Kathleen Machiels,Severine Vermeire,Harry Sokol,Francisco Guarner,Chaysavanh Manichanh +13 more
TL;DR: The results showed that UC and CD are two distinct subtypes of IBD at the microbiome level, and for the first time, microbiomarkers to discriminate between CD and non-CD independently of geographical regions are proposed.
Journal ArticleDOI
Oral oligofructose-enriched inulin supplementation in acute ulcerative colitis is well tolerated and associated with lowered faecal calprotectin
F. Casellas,Natalia Borruel,Antonio Torrejón,E. Varela,María Antolín,Francisco Guarner,Juan-Ramon Malagelada +6 more
TL;DR: This data indicates that inulin and oligofructose promote selective growth of saccharolytic bacteria with low inflammatory potential and have potential to be a source of signaling errors in the immune system.