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Nora D. Volkow
Researcher at National Institute on Drug Abuse
Publications - 1038
Citations - 121498
Nora D. Volkow is an academic researcher from National Institute on Drug Abuse. The author has contributed to research in topics: Dopamine & Addiction. The author has an hindex of 165, co-authored 958 publications receiving 107463 citations. Previous affiliations of Nora D. Volkow include National Institutes of Health & North Shore University Hospital.
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Journal ArticleDOI
Food restriction markedly increases dopamine D2 receptor (D2R) in a rat model of obesity as assessed with in‐vivo μPET imaging ([11C] raclopride) and in‐vitro ([3H] spiperone) autoradiography
Panayotis K. Thanos,Panayotis K. Thanos,Michael Michaelides,Yiannis K. Piyis,Gene-Jack Wang,Nora D. Volkow +5 more
TL;DR: The ARG finding of an attenuation of the age‐related loss of D2R binding corroborates previous studies of the salutary effects of food restriction in the aging process and suggests that the differences in dopamine activity and D1R levels between Ob and Le Zucker rats are modulated by access to food.
Journal ArticleDOI
DRD2 gene transfer into the nucleus accumbens core of the alcohol preferring and nonpreferring rats attenuates alcohol drinking
Panayotis K. Thanos,Nicholas B. Taintor,Seth N. Rivera,Hiroyuki Umegaki,Hiroyuki Ikari,George S. Roth,Donald K. Ingram,Robert Hitzemann,Joanna S. Fowler,S. John Gatley,Gene-Jack Wang,Nora D. Volkow +11 more
TL;DR: It is noteworthy that increasing DRD2 significantly decreased alcohol intake but did not abolish it, suggesting that highDRD2 levels may specifically interfere with the administration of large quantities of alcohol.
Journal Article
A new PET ligand for the dopamine transporter: studies in the human brain.
Nora D. Volkow,Yu-Shin Ding,Joanna S. Fowler,G.J. Wang,J. Logan,Samuel J. Gatley,David J. Schlyer,N. Pappas +7 more
TL;DR: It is demonstrated that [11C]d-threo-methylphenidate binding in the human brain is reversible, highly reproducible and saturable and is an appropriate PET ligand to measure dopamine transporter availability.
Journal ArticleDOI
Therapeutic doses of amphetamine or methylphenidate differentially increase synaptic and extracellular dopamine.
Wynne K. Schiffer,Wynne K. Schiffer,Nora D. Volkow,Joanna S. Fowler,David Alexoff,Jean Logan,Stephen L. Dewey,Stephen L. Dewey +7 more
TL;DR: The similar potencies of MP and AMP to alter synaptic DA, despite their different potencies in raising ECF DA, could reflect their different molecular mechanisms.
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The effect of graded monetary reward on cognitive event-related potentials and behavior in young healthy adults
TL;DR: A difference between the P3 and CNV is suggested; the P 3 is sensitive to the sustained effect of relative reward value, while the CNV does not vary with reward magnitude.