N
Nora D. Volkow
Researcher at National Institute on Drug Abuse
Publications - 1038
Citations - 121498
Nora D. Volkow is an academic researcher from National Institute on Drug Abuse. The author has contributed to research in topics: Dopamine & Addiction. The author has an hindex of 165, co-authored 958 publications receiving 107463 citations. Previous affiliations of Nora D. Volkow include National Institutes of Health & North Shore University Hospital.
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Journal ArticleDOI
Imaging dopamine's role in drug abuse and addiction.
TL;DR: Therapeutic interventions aimed at restoring brain dopaminergic tone and activity of cortical projection regions could improve prefrontal function, enhance inhibitory control and interfere with impulsivity and compulsive drug administration while helping to motivate the addicted person to engage in non-drug related behaviors.
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Dopamine Transporter Occupancies in the Human Brain Induced by Therapeutic Doses of Oral Methylphenidate
Nora D. Volkow,Gene-Jack Wang,Joanna S. Fowler,Samuel J. Gatley,Jean Logan,Yu-Shin Ding,Robert Hitzemann,Naomi Pappas +7 more
TL;DR: Oral methylphenidate is very effective in blocking dopamine transporters, and at the weight-adjusted doses used therapeutically (0.3 to 0.6 mg/kg), it is likely to occupy more than 50% of the dopamineTransporter.
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Decreased striatal dopaminergic responsiveness in detoxified cocaine-dependent subjects.
Nora D. Volkow,Nora D. Volkow,Gene-Jack Wang,Joanna S. Fowler,Jean Logan,Samuel J. Gatley,Robert Hitzemann,A. D. Chen,Stephen L. Dewey,N. Pappas +9 more
TL;DR: The findings challenge the notion that addiction involves an enhanced striatal dopamine response to cocaine and/or an enhanced induction of euphoria and suggest a participation of thalamic dopamine pathways in cocaine addiction.
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Erratum: Neurocircuitry of Addiction
George F. Koob,Nora D. Volkow +1 more
TL;DR: In this paper, an error was made in Figure 4, and a revised Figure 4 is shown below, showing that the error was caused by the use of Figure 4 in Figure 3.
Journal ArticleDOI
The addicted human brain: insights from imaging studies
TL;DR: In this model, during exposure to the drug or drug-related cues, the memory of the expected reward results in overactivation of the reward and motivation circuits while decreasing the activity in the cognitive control circuit, contributing to an inability to inhibit the drive to seek and consume the drug and results in compulsive drug intake.