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Nora D. Volkow
Researcher at National Institute on Drug Abuse
Publications - 1038
Citations - 121498
Nora D. Volkow is an academic researcher from National Institute on Drug Abuse. The author has contributed to research in topics: Dopamine & Addiction. The author has an hindex of 165, co-authored 958 publications receiving 107463 citations. Previous affiliations of Nora D. Volkow include National Institutes of Health & North Shore University Hospital.
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Physician education in addiction medicine.
TL;DR: Improved understanding of the neurobiology underlying addictive behaviors and the effects of psychoactive substances at the neuropeptide, neurotransmitter, and receptor levels has contributed to the development of medications that can significantly improve outcomes among individuals with substance use disorder.
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Functional connectivity density and the aging brain
TL;DR: Resting-state functional connectivity datasets from 913 healthy subjects revealed that normal aging is associated with pronounced decreases in long-range functional connectivity density that map into the default mode (DMN) and dorsal attention (DAN) networks.
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Dopamine D4 receptor, but not the ADHD-associated D4.7 variant, forms functional heteromers with the dopamine D2S receptor in the brain
Sergio González,Claudia Rangel-Barajas,Marcela Peper,Ramiro Lorenzo,Estefanía Moreno,Francisco Ciruela,Janusz Borycz,Jordi Ortiz,Carme Lluís,Rafael Franco,Peter J. McCormick,Nora D. Volkow,Marcelo Rubinstein,Benjamín Florán,Sergi Ferré +14 more
TL;DR: It is postulated that dysfunctional D2S–D4.7 heteromers may impair presynaptic dopaminergic control of corticostriatal glutamatergic neurotransmission and explain functional deficits associated with ADHD.
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Effects of expectation on the brain metabolic responses to methylphenidate and to its placebo in non-drug abusing subjects.
Nora D. Volkow,Gene-Jack Wang,Yeming Ma,Joanna S. Fowler,Christopher Wong,Millard Jayne,Frank Telang,James M. Swanson +7 more
TL;DR: The results suggest the involvement of the ventral cingulate and of the nucleus accumbens in processing expectation for "uncertain drug effects" even in subjects who have no prior experience with the drug.
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Enhanced choice for viewing cocaine pictures in cocaine addiction.
Scott J. Moeller,Thomas Maloney,Muhammad A. Parvaz,Jonathan P. Dunning,Jonathan P. Dunning,Nelly Alia-Klein,Patricia A. Woicik,Greg Hajcak,Frank Telang,Gene-Jack Wang,Nora D. Volkow,Rita Z. Goldstein +11 more
TL;DR: Enhanced drug-related choice in cocaine addiction can be demonstrated even for nonpharmacologic (pictorial) stimuli, which is modulated by alternative stimuli and partly transcends self-reports to provide an objective marker of addiction severity.