Nora D. Volkow

TL;DR: Positron emission tomography (PET) has been shown to be an effective imaging technique to study neurometabolic and neurochemical processes involved in addiction as mentioned in this paper, which has been used to research neurobiological differences in substance abusers versus healthy controls and the pharmacokinetics and pharmacodynamics of abused drugs.

TL;DR: A strategy was devised to reduce noise in the generation of parametric images of the model term related to enzyme or receptor concentration that should be generalizable to other tracers and should facilitate the analysis of group differences.

TL;DR: A species difference in the susceptibility of MAO A to inhibition by clorgyline is suggested and represents an unusual example of where the behavior of a radiotracer in the baboon brain does not predict its behavior in the human brain.

TL;DR: Ginkgo biloba administration did not produce significant changes in brain MAO A or MAO B suggesting that mechanisms other than MAO inhibition need to be considered as mediating some of its CNS effects.

TL;DR: The results indicated that obesity-resistant S5B rats showed greater cocaine CPP than the obesity-prone OM rats, and showed that BC reduced cocaine conditioning effects supporting at least a partial regulatory role of D2R in conditioned responses to drugs.