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Nora D. Volkow
Researcher at National Institute on Drug Abuse
Publications - 1038
Citations - 121498
Nora D. Volkow is an academic researcher from National Institute on Drug Abuse. The author has contributed to research in topics: Dopamine & Addiction. The author has an hindex of 165, co-authored 958 publications receiving 107463 citations. Previous affiliations of Nora D. Volkow include National Institutes of Health & North Shore University Hospital.
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The Healthy Brain and Child Development Study-Shedding Light on Opioid Exposure, COVID-19, and Health Disparities.
TL;DR: The Healthy Brain and Child Development (HBCD) Study will directly investigate the associations of adverse environments and socioeconomic disadvantage with the development of both brain and behavior throughout early childhood and is preparing to deploy a wide range of research tools to study brain development and physical and mental health.
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Upregulation of cannabinoid type 1 receptors in dopamine D2 receptor knockout mice is reversed by chronic forced ethanol consumption
Panayotis K. Thanos,Vanessa Gopez,Foteini Delis,Michael Michaelides,Michael Michaelides,David K. Grandy,Gene-Jack Wang,George Kunos,Nora D. Volkow +8 more
TL;DR: The results suggest that DRD2-mediated dopaminergic neurotransmission and chronic ethanol intake exert an inhibitory effect on cannabinoid receptor expression in cortical and striatal regions implicated in the reinforcing and addictive properties of ethanol.
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Opioid–Dopamine Interactions: Implications for Substance Use Disorders and Their Treatment
TL;DR: Results on how the rewarding effects of cocaine and alcohol are affected in the KO of receptors measured in the studies of Urban (D2R and D3R KO) and Ghitza (mOR KO) suggest alcohol-induced DA increases were greater for men than for women; and the relative contribution of one neurotransmitter over the other might differ.
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Differential effects of anesthetics on cocaine's pharmacokinetic and pharmacodynamic effects in brain.
Congwu Du,Melissa Tully,Nora D. Volkow,Wynne K. Schiffer,Mei Yu,Zhongchi Luo,Zhongchi Luo,Alan P. Koretsky,Helene Benveniste,Helene Benveniste +9 more
TL;DR: It is demonstrated that anesthetics influence cocaine’s hemodynamic and metabolic changes in the brain, and its binding and PK, which highlights the need to better understand the interactions between anesthetic and pharmacological challenges in brain functional imaging studies.
Journal Article
PET imaging of monoamine oxidase B in peripheral organs in humans.
Joanna S. Fowler,Jean Logan,Gene-Jack Wang,Nora D. Volkow,Wei Zhu,Dinko Franceschi,Naomi Pappas,Richard A. Ferrieri,Colleen Shea,Victor Garza,Youwen Xu,Robert R. MacGregor,David J. Schlyer,S. John Gatley,Yu-Shin Ding,David Alexoff +15 more
TL;DR: The deuterium isotope effect is useful in assessing the binding specificity of labeled deprenyl to peripheral MAO B and 11C-L-deprenyl-D2 will be useful for measuring the effects of different variables, including tobacco smoke exposure onMAO B activity in peripheral organs in humans.